Marbug Virus disease and treatment slideshare

Introduction
Spread of Marbug virus disease
Signs and symptoms
Diagnosis
Treatment and prevention

1. MARBUG VIRUS Mythili G Msc.Microbiology BP231523

2. CONTENT INTRODUCTION MARBUG VIRUS DISEASE SPREAD OF MARBUG VIRUS SIGNS AND SYMPTOMS DIAGNOSIS OF MARBUG VIRUS PREVENTION TREATMENT

3. Marburg virus disease is a rare but often fatal illness. There are sometimes outbreaks of it in parts of Africa. You get it from contact with body fluids of infected bats or people. Symptoms include fever, headache, rash, vomiting, bleeding and confusion. Get medical care right away if you’ve been exposed to Marburg and have symptoms. INTRODUCTION

4. Marburg virus disease ( mvd ) is a serious illness that sometimes causes outbreaks in african countries. Symptoms start out flu-like but can progress to severe vomiting, bleeding and neurological (brain and nerve) issues. Outbreaks usually start by spreading from bats or primates (like monkeys) to humans. From there, it can spread from human to human and cause outbreaks. Marburg is a  viral hemorrhagic fever , or a virus that damages blood vessels and causes bleeding. It’s part of the same family of viruses as  ebola . What is Marburg virus disease?

5. Marburg virus spreads through contact with body fluids of infected humans or animals. Body fluids include: Blood. Urine. Stool. Saliva. Human milk. Semen. Vaginal fluids. How does Marburg virus disease spread?

6. Hemorrhagic symptoms include Maculopapular rash, Petechiae , Purpura , Ecchymoses , and Hematomas (particularly around needle injection sites). Contrary to popular assumption, bleeding does not produce hypovolemia Signs and Symptoms of Marburg Virus Disease

7. And does not cause mortality (total blood loss is minimal except during labour ). Instead, mortality occurs as a result of fluid redistribution, Hypotension, Disseminated intravascular coagulation, and Focal tissue necroses caused by multiple organ dysfunction syndromes (mods). Signs and Symptoms of Marburg Virus Disease

8. It can be difficult to clinically distinguish MVD from other infectious diseases such as malaria, typhoid fever, shigellosis, meningitis and other viral haemorrhagic fevers. Confirmation that symptoms are caused by Marburg virus infection are made using the following diagnostic methods: Antibody-capture enzyme-linked immunosorbent assay (ELISA) Antigen-capture detection test Serum neutralization test Reverse transcriptase polymerase chain reaction (RT-PCR) assay Electron microscopy Diagnosis of Marburg Virus Disease

9. Use protective equipment (such as a mask, goggles, apron and gloves) when caring for someone with MVD. Avoid touching any of their body fluids and wash your hands after contact, even if you wear gloves. Avoid contact with anything that may have touched infected body fluids. Avoid touching the body of someone who died from MVD, or use protective equipment if you have to. This includes funeral customs. Prevention

10. Avoid contact with fruit bats and nonhuman primates and the places they live. This includes caves and mines. Don’t eat bush meat (the meat of wild animals). If you’ve recently returned from travel to a place where there’s a Marburg virus outbreak, monitor yourself for symptoms for 21 days. Get medical care right away if you develop symptoms. Isolate yourself from others if you could have Marburg. Prevention

11. Currently, there is no effective marburgvirus -specific therapy for MVD. Treatment is primarily supportive in nature, consisting of minimising invasive procedures, balancing fluids and electrolytes to prevent dehydration , administering anticoagulants early in infection to avoid or control disseminated intravascular coagulation, Treatment of Marburg Virus Disease

12. Administering procoagulants late in infection to control haemorrhaging , Maintaining oxygen levels, Pain management, Administering antibiotics or antifungals to treat secondary infections. Treatment of Marburg Virus Disease

13. https://www.who.int/news-room/fact-sheets/detail/marburg-virus-disease https://byjus.com/current-affairs/marburg-virus-disease-mvd/ https://my.clevelandclinic.org/health/diseases/25097-marburg-virus-disease references

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