Menopause how it happens and tips and tr

Menopause presentation covering various details about it

1. MENOPAUSE

2. What is Menopause? Menopause is a natural biological process, marking the end of women's reproductive years (menstrual cycle). It typically occurs between the ages of 45 and 55 but can vary widely. Menopause is diagnosed after 12 consecutive month without a menstrual period.

3. This is the transition period leading up to menopause. This is the stage defined as the point when a woman has not had a menstrual period for 12 consecutive months. This is the stage after a woman has gone 12 months without menstrual period.

4. Hormonal Changes Associated with Menopause Testosterone levels may decline Testosterone

5. Signs and Symptoms

6. Age: Most significant risk factor. Smoking: Leads to experience menopause earlier Chemo and radiation therapy: Can damage the ovaries leading to earlier menopause Ovarian surgery: Causes immediate menopause Autoimmune disorders: Can influence the timing of menopause BMI: Lower BMI can be associated with earlier menopause Diet and nutrition: Poor diet can influence the onset of menopause Chronic diseases: Can affect the timing and severity of menopausal symptoms Factors Affecting Menopause

7. Balanced diet Regular exercise Adequate sleep Stress management Avoiding triggers Hormone replacement therapy Non-Hormonal medications: 1. Antidepressants 2. Gabapentin 3. Clonidine Acupuncture Herbal supplements Phytoestrogen Isoflavones lignans

8. Soy Products Isoflavones (i.e. a class of phytoestrogens-plant derived compounds with estrogenic activity) Isoflavones ingestion Enters the bloodstream Isoflavones binds to estrogen receptors m imics estrogen activity Reduced estrogen deficiency symptoms and Alleviation of depression, hot flashes and night sweats Improved quality of life symptoms Increased production of serotonin and Beta-endorphins Improved mood Sleep regulation and reduced mood swings, anxiety and Overall reduction in Menopausal symptoms How Do Phytoestrogen Helps In Managing Menopause

9. Flaxseed Lignans Lignans ingestion Enters the bloodstream Conversion to Enterolignans by Gut Microbiota Enterolignans bind to Estrogen receptors Mimic estrogen activity Reduced estrogen deficiency symptoms and Alleviation of depression, hot flashes and night sweats Improved quality of life symptoms Increased production of serotonin and Beta-endorphins Improved mood Sleep regulation and reduced mood swings, anxiety and Overall reduction in Menopausal symptoms (i.e. a class of phytoestrogens-plant derived compounds with estrogenic activity)

10. Phytoestrogen Isoflavones Lignans Isoflavones ingestion Enters the bloodstream Isoflavones binds to estrogen receptors mimics estrogen activity Lignans ingestion Enters the bloodstream Conversion to Enterolignans by Gut Microbiota then binds to estrogen receptor and mimics estrogen activity Reduced estrogen deficiency symptoms Improved mood Improved quality of life Increased production of serotonin and Beta-endorphins Alleviation of depression, hot flashes and night sweats Sleep regulation and reduced mood swings, anxiety Overall reduction in Menopausal symptoms

11. Ingestion of Anethole Absorption in the digestive system Metabolism in the liver to estragole and other metabolites Mechanism Of Anethole Modulation of enzymatic pathways Influence on estrogen metabolism and bio-availability Activation of secondary signaling pathways Alleviation of menopausal symptoms

12. Nutrients Values Energy 377 Protein 37.8 Carbohydrates 10.16 Fats 19.42 Beta-Carotene 2.82 Thiamin 0.61 Niacin 2.28 Riboflavin 0.23 Calcium 195 Iron 8.22 Dietary Fiber 22.63 Isoflavones : It is a class of phytoestrogens- plant derived compound with estrogenic activity. They are type of flavonoid, which are polyphenolic compounds known for their antioxidant properties. High Source of Isoflavones: Soybean Other sources: Tofu, Soy Milk, Soy flour.

13. Nutrients Values Energy 333 Protein 10 Carbohydrates 13.3 Fats 26.6 Beta-Carotene 1.05 Thiamin 0.28 Niacin 1.09 Riboflavin 0.05 Calcium 257 Iron 5.44 Dietary Fiber 26.17 Lignans: Are a group of polyphenolic compounds found in plants. They are considered phytoestrogens, similar to isoflavones. High source of Lignans: Flaxseeds Other sources of Lignans : Sesame seeds, whole grains, legumes.

14. Nutrients Values Energy 337 Protein 17.6 Carbohydrates 50 Fats 0.3 Beta-Carotene - Thiamin 0.34 Niacin 3.06 Riboflavin 0.29 Calcium 646 Iron 37 Dietary Fiber 14.6 Anethole: It is an organic compound that is widely used for its flavor and aroma. It is a type of phenylpropene, a subclass of aromatic compound. High source of Anethole: Anise seed Other sources of Anethole: Fennel, Basil, Star anise.

15. RESEARCH ARTICLE

16. Nutritional Supplement Prepared from Whole Meal Wheat Flour, Soya Bean Flour, Flaxseed and Anise Seeds for Alleviating the Menopausal Symptoms  Authors: Suzanne Fouad, Salwa Mostafa El Shebini, Maha Abdel-Moaty, Nihad Hassan Ahmed, Ahmed Mohamed Saied Hussein, Aliaa El Gendy, Hend Abass Essa and Salwa Tawfic Tapozada    Published: February 22, 2019    Citation: Suzanne Fouad, Salwa Mostafa El Shebini, Maha Abdel-Moaty, Nihad Hassan Ahmed, Ahmed Mohamed Saied Hussein, Aliaa El Gendy, Hend Abass Essa and Salwa Tawfic Tapozada, 2018. Nutritional Supplement Prepared from Whole Meal Wheat Flour, Soya Bean Flour, Flaxseed and Anise Seeds for Alleviating the Menopausal Symptoms. Journal of Biological Sciences, 18: 381-388. 

17. AIM: To help the female’s body to adapt to diminish estrogen hormone around the time of the menopause and to ultimately take control of the symptoms.

18. Methods 51 Volunteers ( Egyptian Females) With the mean age of 46 years Complaining of menopausal symptoms in the perimenopause stage The participants consumed daily 80g of the supplement made with substituting wheat flour with soy flour and addition of flaxseed and anise seed in the form of cookies Chemical analysis of the supplement was carried out Detailed gynecological, obstetric, drugs intake and dietary history were recorded Menopausal symptoms evaluation was carried out using the Menopause Rating Scale(MRS) for evaluation of somatic, psychological and urogenital symptoms Anthropometric measurements, blood pressure were reported Female sex hormones were evaluated

19. Chemical Composition Of The Supplement Formula was prepared by mixing the ingredients according to the table 1 and the suitable amount of water were added . These formulas were baked in an electrical oven at 200 °C for about 20 mins. Weight, volume, diameter, specific volume, diameter, thickness, and spread ration of the cookies were recorded.

20. Results

21. Table 4: Frequency and percentage of menopausal symptoms score before and after intervention

22. Table 6: Percent of the frequency consumption of different food items for the studied sample

23. Soya Supplement

24. Discussion A study focused on enhancing the nutritional value of bakery products like biscuits and cookies using soy flour, flaxseed, and anise seeds. These ingredients were chosen for their health benefits, including increased protein, fiber, minerals, and phytoestrogens. Soy flour and flaxseed enriched the products with essential amino acids, vitamins (A and D), and healthy fats (like linoleic acid). Improved bioavailability of nutrients such as carbohydrates, proteins, and vitamins. Participants experienced significant improvements: Decreased blood pressure, central obesity, and menopause symptoms. Enhanced mental and physical well-being related to menopause.

25. Soy-rich diets have shown lower incidences of heart disease and breast cancer in Asian women compared to Western populations. Soy products, containing compounds like genistein and daidzein, help manage menopausal symptoms and may have anti-aging effects. Previous research supports the benefits of soy products in managing hormonal levels (FSH, estrogen, testosterone) and reducing symptoms related to menopause. Ground flaxseed can be easily integrated into various baked goods, cereals, and nutritional bars. Combining soy flour and flaxseed in bakery products may enhance their health benefits synergistically.

26. Conclusion This study discovers the possible synergetic effect of soya bean flour, flaxseed and anise combination to form a natural bakery product in the form of cookies that can be beneficial for alleviating the somatic, psychological and urogenital symptoms after intervention, especially in somatic and psychological subscales.

27. Bibliography

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