Metabolism of fat involves catabolic and anabolic processes.
catabolic processes that generate energy.
anabolic processes that create biologically important molecules (cholestrol, triglycerides, phospholipids, and ketone bodies, lipoproteins).
Size: 1.24 MB
Language: en
Added: Dec 04, 2018
Slides: 16 pages
Slide Content
METABOLISM OF FAT BY PINKY RATHEE
Introduction Metabolism of fat involves catabolic and anabolic processes. catabolic processes that generate energy. anabolic processes that create biologically important molecules ( cholestrol , triglycerides, phospholipids, and ketone bodies, lipoproteins).
Pathways for metabolism of fat The fat we eat help to enjoy food and also plays important role in body. Fat stores helps as cushion for vital organs and protect nerve cells. Fat is used in body by two pathways:- Endogenous pathway Exogenous pathway
Endogenous Pathway
.
.
.
.
Absorption and transportation:-
.
Endogenous pathway Liver is the main organ which helps in the fat metabolism. There are 5 types of lipoproteins:- Chylomicrons VLDL( very low density lipoprotein) LDL (low density lipoprotein) HDL (high density lipoprotein) Free fatty acids
Cont … Every cell needs cholestrol (main source of energy) so liver continuously produces VLDL. LDL are having decreased density of protein and increased density of lipids HDL go around body interacting with other lipids particles in cells and picking up stray cholestrols .
Cont … When cholestrol become oxydised it become sticky and stagnant over artery walls. In blood stream, macrophages helps in keeping up dead particles or debries , if arterial walls are diseased, more macrophages try to keep the endothelial intact. VLDL become degraded as they pull out various aspects of cholestrol & may result into LDL
Cont … LDL (primary cholestrol ),macrophages grab the LDL, as debries because of its oxydation & starts to feed on them and create a waxy atheroma causing hypercholesrolemia and dislipidemia . VLDL is inversely proportional to HDL. VLDL supplies triglycerides and cholestrol . 50% of cholestrol is degraded by bile.