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1. Introduction Professor Dr. Haider Faisal Ghazi

2. Immunology Course Description Course Title Immunology Course Code MICImm:31 Course Instructor Professor Dr. Ahmed Abdul- hassan Abbas Course Coordinator Professor Dr. Haider Faisal Ghazi Lecturer Mohammed Razak Ali

3. Immunology Course Objectives & Description  Course Objective To provide a basic knowledge of the immune response and its involvement in health and disease.   Course Description   Introduces the principles of immunology including: Development of the immune system, innate immunity, immunoglobulin structure and genetics, antigen-antibody reactions, the major histocompatibility complex reactions and antigen presentation, T cell activation, cytokines, phagocytic cell function, immune responses to infectious organisms and tumors, autoimmune diseases, allergies, and immune deficiencies

4. Immunology Course Reference and Marks Textbook Owen J, Punt J, Stranford S, Jones P. Kuby Immunology. Macmillan Learning; 2022.   Course Assessment Mid term 30 marks  10 marks Quizzes 20 marks mid term exam  Final Laboratory exam 20 marks   Final theory Exam 50 marks Total 100 marks

5. Key message of the topic Immunology is one of the medical sciences concerning host defense mechanisms against foreign substances. Lecture statement

6. Relevant clinical scenario to the lecture topic (preferable). Case scenario

7. Define the science of immunology. Understand terms of immunology, immunity and immune response. Understand the need for immunity. Define types of immunity. Know the factors affecting immunity. Objectives

8. Definition of Immunology, immunity and Immune response. Why we need host protection? Types of Immunity. Time course of immune response Factors affecting host immunity Lecture skeleton

9. Immunology is a branch of biomedical sciences that study host defence against infectious diseases and foreign (non-self) antigens. composed of many cell types, the majority of which are organized into separate lymphoid tissues and organs.

10. Immunity Continuous dynamic process of normal (physiological) protective mechanisms (Anti infective) ensuring body health and normal processes. Other wise, It will be abnormal: Immunodeficiency. Hypersensitivity. Autoimmunity. Failure in monitoring of abnormal growth (tumors).

11. Why we need protection?????

12. types of immunity Innate immunity Adaptive immunity 1 st line of defense Ready to be activated upon recognition. None specific No memory 2 nd line of defense Develops more slowly Specific Memory

13. Factors affecting immu nity : Genetics. Age. Protein–calorie malnutrition or deficiency of vitamin A, vitamin C, and folic. acid makes an individual highly susceptible to infection by many microbial pathogens.

14. Factors affecting immun ity : 4. Hormonal levels: an increase in corticosteroids decreases the inflammatory response and lower the resistance to infection. 5. Oxygen tension, which is especially high in the lung and inhibit the growth of anaerobic bacteria . 6. Body temperature, many organisms does not infect human because they cant grow at 37.

15. ? Students questions

16. Immunity is essential for human survival Two types of immune responses will ensure complete protection Why immune response were different in their strength among us? SUMMARY

17. Thank you