Mongolian spot

Neonatal skin provides physical protection and allies in fluid balance, immunosurveillance and thermoregulation, thus playing a crucial role in the newborn’s transition from an aqueous to an air dominant milieau. Quiet large number of changes from transient physiological to grossly pathological lesions are observed in the skin of a neonate. The majority of the disorders in the newborn are physiological, transient and self-limited and majorly require no therapy. Mongolian spot is found as blue, green spot majorly on the shoulders and lower part of the body, scientifically Mongolian spots can be delineated as deep dermal melanocytes present in the collagen bundle. The color is generally the same over the whole birthmark, with no lighter or darker areas as is sometimes seen in brown birthmarks. Mongolian blue spots are can differ in size, but most are a few centimeters across. They can appear anywhere on the body, but are most generally noted at the base of the spine, the buttocks or on the lower back. In addition, they are present on the back of the shoulder. It is very unusual for a child to have a Mongolian blue spot on the scalp or face.

1. Mongolian Spot SREEREMYA.S ASSISTANT PROFESSOR DEPT OF BIOTECHNOLOGY SREE NARAYANA GURU COLLEGE

2. Neonatal skin provides physical protection and allies in fluid balance, immunosurveillance and thermoregulation, thus playing a crucial role in the newborn’s transition from an aqueous to an air dominant milieau . Quiet large number of changes from transient physiological to grossly pathological lesions are observed in the skin of a neonate. The majority of the disorders in the newborn are physiological, transient and self-limited and majorly require no therapy. Mongolian spot is found as blue, green spot majorly on the shoulders and lower part of the body, scientifically Mongolian spots can be delineated as deep dermal melanocytes present in the collagen bundle.

3. INTRODUCTION It is a type of birthmark that is present at birth or may appears soon afterwards, either single or multiple in number. It is flat, blue-grey in color and can differ from a very dark blue to a lighter grey.

4. The color is generally the same over the whole birthmark, with no lighter or darker areas as is sometimes seen in brown birthmarks. Mongolian blue spots are can differ in size, but most are a few centimeters across. They can appear anywhere on the body, but are most generally noted at the base of the spine, the buttocks or on the lower back. In addition, they are present on the back of the shoulder. It is very unusual for a child to have a Mongolian blue spot on the scalp or face.

5. Mongolian Blue Spot Mongolian Blue spots have led to a small number of families being inappropriately referred causing pivotal distress and inconvenience. Such birth marks are sometimes not being indicated and in particular are often not documented in the child records when first seen (Upshaw et al., 1947) [1]. Incidence Almost universal in non-Caucasian neonates. Specifically obvious in Asian infants and occasionally also occurs in Caucasian infants with dark hair.

6. Clinical State Grey or bluish pigmentation, generally in the features lumbosacral region, but may occur anywhere on the trunk or limbs. Prognosis Becomes less obvious as the infant grows older (Allen, 1949) [2]. Erythema Toxicum ( Urticaria of Newborn , Eosinophil Rash) Incidence Extremely common, except in preterm infants. Generally, infants are affected in first week of life. Etiology Vesicles are full of eosinophils . Clinical Features Widespread, fluctuating erythematous maculopapular rash, generally beginning after birth at any time in the first week.

7. refernce Mongolian Spot S . Sreeremya * International Journal of Genetic Engineering and Recombination Vol. 3: Issue 1