MYOPIA , basics , causes , types and treatment

Myopia, also known as near-sightedness and short-sightedness, is an eye disease[5][6][7] where light from distant objects focuses in front of, instead of on, the retina.[1][2][6] As a result, distant objects appear blurry while close objects appear normal.[1] Other symptoms may include headaches and eye strain.[1][8] Severe myopia is associated with an increased risk of macular degeneration, retinal detachment, cataracts, and glaucoma.[2][9]

Myopia results from the length of the eyeball growing too long or less commonly the lens being too strong.[1][10] It is a type of refractive error.[1] Diagnosis is by the use of cycloplegics during eye examination.[11]

Tentative evidence indicates that the risk of myopia can be decreased by having young children spend more time outside.[12][13] This decrease in risk may be related to natural light exposure.[14] Myopia can be corrected with eyeglasses, contact lenses, or by refractive surgery.[1][15] Eyeglasses are the simplest and safest method of correction.[1] Contact lenses can provide a relatively wider corrected field of vision, but are associated with an increased risk of infection.[1][16] Refractive surgeries like LASIK and PRK permanently change the shape of the cornea. Surgeries like Implantable Collamer Lens (ICL) implant a lens inside the anterior chamber in front of the natural eye lens. ICL doesn't affect the cornea.[

1. MYOPIA Presented By – Dr Mohit Kumar Jha Ophthalmology Resident Civil Hospital , Panchkula

2. SHORT SIGHTEDNESS DIOPTERIC CONDITION IN WHICH INCIDENT PARALLEL RAYS COME TO A FOCUS ANTERIOR TO THE LIGHT SENSITIVE LAYER OF RETINA WITH ACCOMODATION AT REST . MYOPIA

3. Axial myopia Commonest form Increase in antero-posterior length of the eyeball Curvatural myopia Increased curvature of cornea, lens or both Positional myopia Produced by anterior placement of crystalline lens in eye Index myopia Increase in the refractive index of crystalline lens associated with nuclear sclerosis Myopia due to excessive accomodation ETIOLOGICAL CLASSIFICATION

4. Congenital myopia Simple or developmental myopia Pathological or degenerative myopia Acquired myopia CLINICAL CLASSI.FICATION

5. AGE ONSET CLASSI. CONGENITAL : since birth YOUTH ONSET : Below 20 yrs. ( Simple Myopia) EARLY ADULT ONSET: 20-40: Acquired Index myopia d/t Early NS LATE ADULT ONSET: 40+ d/t Age NS

6. Since birth Diagnosed by 2-3 years Mostly unilateral - Manifests as anisometropia High degree of error: -8 to-10 D Prematures, Marfan Sy, Homocystinuria Associated with cataract, micropthalmos , aniridia, megalocornea , congenital separation of retina CONGENITAL MYOPIA

7. Developmental myopia- commonest variety School myopia (school going age 8 -12 years) Etiology Axial type : physiological variation in length of eye ball SIMPLE MYOPIA Curvatural type Underdevelopment of eye ball Role of diet in early childhood Role of genetics – Autosomal Dominant Prevalence in children both parents myopic(20%) One parent myopic(10%) No parent myopic(5 %)

8. SYMPTOMS Begins bet. 7 to 10 yrs. – about -5D, never exceeds -8D. POOR VISION FOR DISTANCE HALF SHUTTING OF EYES: Stenopaeic vision ASTHENOPIC: Pts with small degree of myopia- Strain symp. Convergence weakness, Exophoria , diplopia

9. Signs Prominent eyeballs Anterior chamber - deeper than normal Pupils- Large, sluggishly reacting Fundus- normal; temporal myopic crescent may be seen Magnitude of refractive error Increasing at rate -0.5+- 0.30/ year. Does not exceed 6 to 8 Diagnosis Confirmed by performing retinoscopy

10. Degenerative/ progressive myopia Rapidly progressive error which starts in childhood at 5-10 years of age High myopia in early adult life with degenerative changes PATHOLOGICAL MYOPIA

11. Role of heredity Heredity linked growth of retina is the determinant in developmental myopia Sclera due its distensibility follows retinal growth but choroid undergoes degeneration due to stretching, which in turn causes degeneration of retina Progressive myopia is Familial More common in chinese,japanese,arabs and jews Uncommon among negroes,nubians and sudanese ETIOLOGY

12. Genetic factors (play major role) General growth process(minor) More growth of retina Stretching of sclera Increase axial length Degeneration of choroid Degeneration of retina Degeneration of vitreous

13. Defective vision - uncorrectable loss of vision Muscae volitantes Floating black opacities in front of eyes Degenerated liquified vitreous SYMPTOMS

14. Prominent eye balls Elongation of eye ball mainly affects posterior pole and surrounding area Cornea-large Anterior chamber -deep Pupils-slightly large ,react sluggishly to light SIGNS

15. Fundus examination: Optic disc large and pale Temporal edge presents a characteristic myopic crescent - Atrophy of choroid - sclera visible Peripapillary crescent encircling the disc may be present, where choroid and retina is distracted away from disc margin Super traction crescent may be present on nasal side (retina pulled over disc margin)

16. Degenerative changes in retina and choroid Common in progressive myopia Characterized by white atrophic patches at macula with a little heaping of pigment around them

17. FOSTER-FUCH’S SPOT: Dark red circular patch due to sub- retinal neo vascularization and choroidal haemorrhage Present at macula

18. Posterior staphyloma Due to ectasia of sclera at posterior pole It may be apparent as an excavation with vessels bending backward over margins

19. Degenerative changes in vitreous include: Liquefaction Vitreous opacities Posterior vitreous detachment(PVD)- Weiss’ reflex

20. Retinal detachment /Tears Myopic choroidal neovascularisation NS Vitreous haemorrhage COMPLICATIONS

21. SECONDARY MYOPIA INDEX: Nuclear Sclerosis Incipient Cataract Diabetic Myopia CURVATURAL: Corneal- Ectasis, Keratoconus POSITIONAL- Ant. Subluxation of lens CONSECUTIVE- surgical overcorrection of Hypermetropia, IOL

22. DRUG INDUCED- Cholinergic – Pilocarpine, Echothiophate , Steroid Sulphonamides

23. Optical treatment of myopia Concave lenses Basic rule – minimum acceptance providing maximum vision Modes of prescribing concave lens- Spectacles Contact len s TREATMENT OF MY OPI A

24. Contact lenses are used in case of high myopia as they avoid peripheral distortion and minification produced by strong concave spectacle lens

25. Radial keratotomy Making deep radial incisions in peripheral part of cornea leaving the central a 4mm optical zone These incisions on healing ; flatten the central cornea thereby reducing its refractive power Correct low to moderate myopia(2-6D) DISADVANTAGES : Cornea is weakened – globe rupture in sports persons Uneven healing – irregular astigmatism Patient may feel glare at night SURGICAL TREATMENT OF MYOPIA

26. Photo refractive keratectomy (PRK) A central optical zone of anterior corneal stroma is photoablated using excimer laser (193nm uv flash) to cause flattening of central cornea Correction for -2 to - 6D of myopia

27. Di s a d vanta g es: Post operative recovery is slow Pain and discomfort Residual corneal haze in centre affecting vision Expensive

28. Refractory surgery of choice for myopia of upto -12D LASER ASSISTED IN-SITU KERATOMILEUSIS (LASIK)

29. Flap of 130-160 micron thickness of anterior corneal tissue is raised Midstromal tissue is ablated directly with an excimer laser beam ultimately flattening the cornea

30. Patients >20 years Stable refraction for at least 12 months Motivated patient Absence of corneal pathology Absolute contraindication for LASIK Presence of ectasia Corneal thickness <450mm PATIENT SELECTION CRITERIA

31. Customised(C)-LASIK: Based on wave front technology Corrects spherical, cylindrical and other aberations present in eye Gives vision beyond 6/6 i.e.,6/5 or 6/4 ADVANCES IN LASIK

32. Epi-(E) LASIK: Only epithelial sheet is separated with Epiedge Epikeratome Devoid of complications related to corneal stromal flap

33. Minimal or no postoperative pain Recovery of vision is very early as compared to PRK No risk of perforation during surgery and rupture of globe due to trauma like RK No residual haze unlike PRK where subepithelial scarring may occur LASIK is effective in correcting myopia of -12D ADVANTAGES OF LASIK

34. Expensive Requires greater surgical skill than RK and PRK Flap related complications Intraoperative flap amputation Wrinkling of flap on repositioning Postoperative flap dislocation/subluxation Epithelization of flap – bed interface Irregular astigmatism DISADVANTAGES

35. Intraocular contact lens implantation for correction of myopia of >12D Special type of IOL is implanted in anterior chamber or posterior chamber anterior to natural crystalline lens PHAKIC INTRAOCULAR LENS

36. Into the peripheral cornea at approximately 2/3 rd stromal depth Flattening of central cornea, decreasing myopia Advantage: reversible procedure INTRACORNEAL RING (ICR) IMPLANTATION

37. A non-surgical reversible method of molding the cornea with overnight wear unique rigid gas permeable contact lenses Myopia correction upto -5D Used in patients below 18 years of age ORTHOKERATOLOGY

38. General measures : Balanced diet rich in vitamins and proteins Early management of associated debilitating disease Low vision aids indicated in patients with progressive myopia with advanced degenerative changes Prophylaxis Genetic counselling

39. Thank you