IRON FORTIFICATION Ferrous sulphate was enough to fortify salt with iron Consumed for 12 to 18 months reduced anaemia OTHER STATEGY Diet control of parasite and nutritional education 10
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Vitamin D is not just Fat-soluble vitamin is prohormone that is synthesized in the skin after exposure to ultraviolet radiation, or absorbed from food sources or supplements. The prohormone is then serially converted to the metabolically active form in the liver and subsequently the kidneys 13 Vitamin D insufficiency and deficiency in children and adolescents
Cholecalciferol , or vitamin D 3- animal products Ergocalciferol , or vitamin D 2 - plant dietary Calcidiol (25-hydroxyvitamin D [25OHD]), is the storage form of vitamin D Calcitriol (1,25-dihydroxyvitamin D or 1,25[OH] D), is the active form of vitamin D 14 The main forms of vitamin D are:
Recommendations for vitamin D intake in healthy individuals are endorsed by National Academy of Medicine (NAM) and the American Academy of Pediatrics (AAP) Infants (born at term) – 400 international units (10 micrograms) daily. Infants who are exclusively breastfed require vitamin D supplements to achieve this target, as do some formula-fed infants. Children 1 to 18 years of age – 600 international units (15 micrograms) daily. 15 TARGETS FOR VITAMIN D INTAKE
Rickets Osteomalacia higher risk of upper respiratory infections food allergies and asthma. childhood dental caries cardiovascular disease, hypertension cancers such as breast, prostate, and colon cancer 16 Associated conditions
Vitamin D replacement — therapy is necessary for children presenting with low levels of 25-hydroxyvitamin D Either vitamin D2 (ergocalciferol) or vitamin D3 (cholecalciferol) may be used Dosing – based on Global Consensus recommendations on prevention & management of nutritional rickets Infants <12 months old – 2000 IU daily for 6 to 12 weeks, followed by maintenance dosing of 400 IU daily Children ≥12 months old – 2000 IU daily for 6 to 12 weeks, followed by maintenance dose of 600 to 1000 IU daily Children ≥12 years old – 6000 international units (150 micrograms) daily for 12 weeks Multiple dosing regimens Stoss therapy – Short-term administration of high-dose vitamin D To prevent hypocalcemia, calcium replacement should be given at doses of 30 to 75 mg/kg/day of elemental calcium, in two or three divided doses 17 TREATMENT