Neuroendocrine Tumours ( N E Ts )

Neuroendocrine tumours (NETs) are a unique group of cancers that originate from neuroendocrine cells — specialized cells with features of both nerve cells and hormone-producing cells. These tumours can develop in various parts of the body, most commonly in the gastrointestinal tract, pancreas, and lungs. Although often slow-growing, some NETs can be aggressive and require timely medical evaluation and treatment.

1. Neuroendocrine Tumours (NETs)
By Dr. Sachin Arora, MBBS, MS, M.Ch. (Surgical Gastroenterologist)

Neuroendocrine tumours (NETs) are a unique group of cancers that originate
from neuroendocrine cells — specialized cells with features of both nerve cells
and hormone-producing cells. These tumours can develop in various parts of
the body, most commonly in the gastrointestinal tract, pancreas, and lungs.
Although often slow-growing, some NETs can be aggressive and require timely
medical evaluation and treatment.

2. Understanding Neuroendocrine Tumours
Neuroendocrine cells play a crucial role in regulating numerous bodily functions
by releasing hormones into the bloodstream. When these cells begin to grow
abnormally, they form neuroendocrine tumours, which may secrete excessive
hormones, causing a range of systemic symptoms.
A common type of NET is the Carcinoid Tumour, typically found in the
intestines, lungs, or other parts of the digestive system. These tumours can
sometimes spread (metastasize) to other organs, such as the liver, making early
detection vital.
Common Symptoms
Symptoms of neuroendocrine tumours vary depending on the tumour’s location
and whether it produces hormones. Often, early stages may go unnoticed.
However, key warning signs include:
Abdominal pain: Persistent or intermittent pain due to tumour growth or
intestinal obstruction.
Diarrhea or digestive issues: Caused by excessive hormone release affecting
bowel movement.
Flushing of the skin: Sudden redness or warmth, especially on the face and
neck, due to hormone secretion.
Unexplained weight loss: Caused by metabolic changes and poor nutrient
absorption.
Hormonal changes: Manifested through irregularities in metabolism, mood, and
general health.
These symptoms can mimic other digestive conditions, making expert
evaluation essential for accurate diagnosis.

3. Diagnosis
Diagnosis of NETs typically involves a combination of:
Imaging tests: CT scan, MRI, and PET scans to detect the tumour and assess
spread.
Endoscopic procedures: Visualization and biopsy of gastrointestinal lesions.
Blood and urine tests: Measurement of hormone levels and tumour markers
such as chromogranin A.
Histopathological analysis: To determine tumour type, grade, and
aggressiveness.
Treatment Options
Treatment for neuroendocrine tumours depends on tumour size, location,
spread, and hormone activity. A multidisciplinary approach ensures the best
outcomes.
Surgery (Laparoscopic Removal):
Whenever feasible, surgical excision remains the most effective treatment for
localized NETs. Minimally invasive laparoscopic surgery offers faster recovery,
less pain, and better cosmetic outcomes.
Targeted Therapy and Chemotherapy:
In advanced or metastatic cases, targeted therapy drugs and chemotherapy are
used to inhibit tumour growth and control hormone production.
Hormone-Controlling Medicines:
Medications such as somatostatin analogues help manage symptoms like
flushing and diarrhea by reducing hormone secretion.
Regular Follow-up and Imaging:
Continuous monitoring with imaging and lab tests ensures early detection of
recurrence or metastasis.
Comprehensive Care Approach

4. Managing NETs requires expert coordination between surgeons, oncologists,
radiologists, and endocrinologists. The goal is not only to remove the tumour
but also to improve quality of life and manage hormone-related symptoms.
At Dr. Sachin Arora’s Surgical Gastroenterology practice, patients receive
personalized care combining advanced diagnostics, minimally invasive surgical
techniques, and evidence-based medical therapy.
Why Choose Dr. Sachin Arora
Dr. Sachin Arora is a highly skilled Laparoscopic Gastrointestinal, HPB (Hepato-
Pancreato-Biliary), and Gastrointestinal Cancer Surgeon with extensive
experience in managing complex abdominal and hepatobiliary disorders. He
specializes in laparoscopic and robotic surgery for gastrointestinal and
neuroendocrine tumours, ensuring safe, precise, and effective treatment
outcomes.
Contact & Consultation
For expert consultation and treatment of Neuroendocrine Tumours,
Contact:
Address :- GEIMS, 16th Milestone, Chakrata Road, Dehradun (UK)
Sanjay Medicos, Ballupur Chowk, Dehradun (UK)
Mobile :- [phone]
Website :- https://drsachinarora.in/
Early detection and timely intervention are key to successful management of
Neuroendocrine Tumours. If you experience persistent digestive or hormonal
symptoms, consult a qualified gastroenterologist without delay.