NIPAH VIRUS (preventive and social medicine)

This presentation is preferably apt for medical undergraduates, who are studying preventive and social medicine as their subject. This may be used for understanding the topic, as well as presenting it in a seminar.

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2. Describe, in relation to nipah virus, the following: Epidemiological burden Mode of transmission Clinical manifestations Diagnosis Treatment Prevention 2 LEARNING OBJECTIVES

3. Emerging infectious disease Zoonotic Virus Family – Paramyxoviridae Genus – Henipavirus 3 ‘NIPAH’ – derived from the village in Malaysia, where the person from whom the virus was first isolated, succumbed to the disease in 1999 INTRODUCTION

4. 4 1 st Isolated & Identified – 1999 (among pig farmers in Malaysia & Singapore) Later identified – 2001 (in Bangladesh & India) Recent outbreak – Kerala in 2018 : 19 cases with 17 deaths

5. (Family Pteropodidae ) Incubation period: 4- 14 days TRANSMISSION 5

6. CLINICAL MANIFESTATIONS 6

7. 7 RESPIRATORY NEUROLOGICAL Cntd .

8. RT-PCR ELISA -Antibody detection PCR assay Virus isolation by cell culture RT-PCR ELISA- Antibody detection PCR assay Virus isolation by cell culture DIAGNOSIS 8

9. No specific drug or vaccine available. Supportive care for severe respiratory or neurological complications. 9 TREATMENT

10. By raising awareness in people about : Risk factors Measures to reduce exposure to nipah virus 10 PREVENTION

11. 11 TAKE HOME MESSAGE

12. K.Park - Textbook of Preventive and Social Medicine WHO (2018) factsheet nipah virus Communicable diseases watch, vol.15 Centers for Disease Control and Prevention Google images 12 REFERENCES

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