Nutraceuticals

important of nutraceuticals in pharmacy field for beneficial effect, herbal foods, useful effects in human beings, anticancer activity, fertility activity, anti diabetic activity, scope of nutraceutical market in INDIA

1. Nutraceuticals Ravikumar R Patil Asst.Professor LNBC Institute of Pharmacy, Raigaon , Satara

2. What is Nutraceuticals ??? Combination of 2 words Nutrition + pharmaceuticals Means “Food or Food Products” + “Medical Benefits”

3. Intro It’s a group are more than a food & less than pharmaceuticals. According to FSSA Nutraceuticals are : - “ Foods which provide health benefits to reduce the risk of chronic diseases & basic nutrition .”

4. Cont.. Nutraceuticals may be used as dietary supplements or as a functional food. These are: natural foods antioxidants dietary supplements citrus fruits vitamins minerals herbals milk & cereals fortified dairy products

5. Cont.. Simply, “ Nutraceuticals ” are the substances which may be regarded as a food or food part which may provide health benefits or medical benefits ( which helps ) for prevention & used in treatment of disease. These products are generally consumed without a medical prescription & supervision.

6. IMPORTANCE Or SCOPE In the dietary supplement nutraceutical products one of the largest market which occupies the 64% in the market. In the pharmaceutical sector nutraceutical products mainly involved in vitamin & mineral section. In INDIA government also funding in vitamin enrichment initiatives for increasing food security concerns in INDIA. Increasing industry regulation worldwide, new product launches & an upswing in acquisition are promoting global nutraceutical market value & growth.

7. Important function of Regulation Bodies In Nutraceuticals (R & D) To test: safety, purity & potency of products. To develop: effective & capable of producing ingredients use in products. To develop: new products either by combining existing ingredients used in nutritional supplements or determining new ingredients. To develop: testing methods for ensuring the uniformity of the ingredients in the company’s products. IMPORTANCE Or SCOPE

8. BENEFITS OF NUTRACEUTICAL PRODUCTS In that products included vitamins, lipids, carbohydrate, minerals & other nutrients. These products are also used with health benefits & reduce the risk of cancer, BP, high cholesterol, excessive weight, diabetes, arthritis, cataracts, menopausal symptoms, insomnia, digestive upsets, constipation etc. Vegetables, fruits, whole grains, nuts, seeds used in treatment of disease conditions. Food derivatives like, garlic, cabbage, soybean, ginger are used in the treatment of cancer.

9. Many other benefits like: To help us live longer. To stay away from particular medical conditions. Increases the health value of our diet. Its not produce unpleasant side effects. Increases the health value of our diet. It also help doing personally for psychological benefits. BENEFITS OF NUTRACEUTICAL PRODUCTS

10. NUTRACEUTICAL PRODUCTS 2 types of nutraceutical products available in the market: Functional Foods Dietary Supplements

11. FUNCTIONAL FOODS (NATURAL FOODS) Functional foods are allow to customers for eat enriched foods which are natural in nature. These foods are either enriched or added in that & these process is called “Nutrification” (addition of nutrients to foods at such a level as to make a major contribution to the diet. e.g Vit.D in Milk) These food gives a specific medical benefits along with nutritional effects. Functional foods included fruits, vegetable juices & drinks, noncarbonated drinks like water, tea, coffee, herbal tea, sports drinks, energy drinks & added omega in ionized salt & wheat flour. DIETARY SUPPLEMENTS (PRODUCING) A dietary supplement is a product that contains nutrients derived from food products & concentrated in liquid, capsules, tablets, powders, gels. These product contains a dietary ingredients proposed to supplement in the diet. In that included vitamins, minerals, herbs, amino acids. These products are not proposed to diagnose, treat, cure or prevent any disease. Dietary supplements products do not approved by FDA.

12. HERBS AS HEALTH FOOD

13. ALFA ALFA Chlorophyll present in alfaalfa . Chlorophyll is powerful substance for healing skin problems. Its also known father of all foods Their leaves are safer than seeds BENEFITS: Maintain healthy skin, skin cleaner ,Contain Vit-B1 & Vit-B6 for healthy hair, Vit -C & Vit -E also present & it increases the blood circulation to scalp & result to healthy hairs. Controls cholesterol, treats in digestive problems, Prevents cancer, Diuretic properties so prevent from UTI. - In that contain Vit -K, Iron used for production of extra Blood & treat in bleeding gums, nosebleeds, anemia - Used in menopausal, Increase immunity, controls sugar Level, Helps in weight loss.

14. CHICORY It’s leaves, flowers used as salads. Their roots used for coffee substitute, pet food. Its great source of Vit-A,B6,C,E & K, & minerals like zinc, magnesium, calcium, iron-folic acid, potassium. In roots contains: Inulin , coumarins , flavonoids , lactones, tannins, vit ., minerals & volatile oil. BENEFITS Helps in digestion Improves heart health Used as anticancer Reduces arthritis pain Reduces weight Treats on constipation Improve immunity Treats kidney disorders Relives anxiety

15. Ginger In raw ginger contains: 79%H2O, 18% Carbohydrate, 2% Proteins, 1% Fat & Vit-B6. Its very useful effect on inflammation & as antioxidant effect. BENEFITS: Reduce muscle pain Anti-diabetic, reduce cardiac diseases Reduce cholesterol level Prevent cancer Antibacterial Helps in respiratory infection In treating nausea & vomiting Reduce menstrual cramp

16. FENUGREEK Fenugreek contains chemical constituents like steroidal Sapogenins & Disogenin . In that 23-26% proteins, 6-7% fat & 58% carbohydrates . In leaves contains 86.1% moisture, 4.4% protein, 0.9% fat, 1.5% minerals, 1.1% fiber & 6% carbohydrate. In leaves contains calcium, zinc iron, phosphorous, riboflavin, thiamine, niacin & Vit -C. BENEFITS: To Enhance milk production in new mother. To maintain blood sugar levels To boost libido (in both men & women) To treat on skin as a anti-inflammatory Maintain liver & kidney health Balance cholesterol Reduce menstrual cramps

17. GARLIC In garlic contain Allicin . When garlic is chopped or crushed, allinase enzyme is activated & produces allicin from alliin . Allicin is the major bioactive compound present in aq extract or raw garlic. BENEFITS: Anti-diabetic, reduce cardiac diseases Reduce cholesterol level Prevent cancer Antibacterial Anti- protozoal Antifungal Improve digestive system

18. HONEY Bees produce honey from the floral nectar or from secretions of other insects like honeydew by regurgitation, enzymatic activity & water evaporation. Glucose & fructose present in it. BENEFITS: Wound healing agent Anti-diabetic Anti-cancer Anti-asthmatic Reduce the risk of coronary heart disorder Treats on neurological diseases Treats on gastrointestinal diseases

19. AMLA In that contain main source of Vit -C, minerals & amino acids. In the fruits contains more than 3 times proteins & ascorbic acid 160 times more than compared to apple. BENEFITS: Immunity booster Treatment on respiratory disorders Anti-diabetics Cure eye disorders Prevents aging Cures anemia Improve digestive system Stimulate the urinary system Good for the skin & hairs Remedy for scurvy

20. GINSENG All parts of ginseng contain active content but main ingredient present in its root. In dried roots contain saponins , oils, carbohydrate, sugar, organic acid, nitrogen, amino acids, vitamins, minerals, enzymes. There are 13 saponins known as ginsenosides or panaxosides . BENEFITS: Treat on Alzheimer disease Improves the lung function Improves mental function Improve sexual function in male Anti-diabetic Increase energy

21. ASHWAGANDHA The main chemical constituents are withanolides , withaferin A, alkaloids, steroidal lactones, tropine & cuscohygrine . Withanolides are similar to ginsenosides of Panax ginseng. BENEFITS: Reduces stress & improve body & brain function Anti-cancer Reduces the cortisol level ( cortisol : stress hormone) Boost testosterone & increase fertility in men Increase muscle mass & strength Reduce inflammation & lower cholesterol & triglycerides

22. SPIRULINA Is basically an alga. In that high contain of protein, vit , vit-B12, minerals, iron, provitamin A ( β -carotenes). Phenolic acid, tocopherols & γ - linolenic acid. BENEFITS: Reduces high cholesterol Treat on nasal allergic Anti-diabetic Anti-cancer Treat on anemia Improve muscle strength