Organozinc compounds hand written notes

Preparation, types and reactions

1. ORSANOBINE compounds oe

¿Omara de compoinda are esp reactive rara |

do grite ar Ggrand ~weagents Stace
ate Gén bord fa highly covalent

[e=2|
25 — 1-6 Els 267. Tonto

chewacter

je Because of desa mattity & Mb content dhasadır

age lowe preparation of fienctfonallzed
detivadives,

+ The fax rg Boe cornpourd AdPathyletoc
Ein) 008 prepared bx Edword Frrankbrad

qa 1844 and wip was also Abe HPA: corpus |
th wetal — carbon m brad

ol wap do prepare ttyl wadical

by æautrg grasuhted fn and ethyl Todtde
oduced Abe Fluss "año

cexepoundg, "yl fre odie

A Faumkdand go

But ase mation pri
¿rap ésperéroetellfe
ard afettpt Frc.

> 22
ax LD port 229 [a consent]

Gig Barats EE

2. PF mors organo comprado; “Ore + phveptente, 2
Seite 0 omfdotfn 2. undergo decompostitny
Rth profe Polea, ; y

% Hence, Aten eve prepared Fo ¿tu cod “reaching
rare foent atmosphere N/A).

x omo Bre compounds; ane dagstffed Rato Hare
àypes. a

w Bforgamäine => R-20R Coro Lepe)
La ‘orpecrosne raledes >. R- zo Lieteve pit)

(9 Metal Preakes > MOR, 22 (m/m)
Ed
rente organo Sue

Porton 2%
a organos compeurda eve generally pepemei
ba creacion of puma ant Secondary toldos

vith Bec metal. fe. onfdotie addition, a

a ke, =

Ces)
Rn Co

dw

3. AED

“faced bx Argales weackten of
pice taie EH BE En Ro

¿Ren Han O Rem A ANR

OA)
ge
2 Dar + Body (Ay + 203 ue"
>

Tunefoneliged, ¢ Arda, are prepared bs

*

Rage Zen exchange "reacio cataluged bu

eur,

FG Roa > (Fra) 20

2
Ducs shoo tolle ont AP ppt bu
an oe pm & Secondary to)?des
ut RfeKe 2fac
13 aa
y A 7 a
2 E y Tri rad

Re adel ao, Congo!

fe e

4. » Omyrro 2frcakes amt geverally prepared Be tte]
raten af Ze halite uth hie cave |
of MALL Mem (om) Gágcard reagent

Boxy + 38m

> Rez
Ent, 93
From Alatorre mation of orgaro lito]

Er gol weagent whi diongrre Zee

ang, + Ro ———— ZRg lm

In: 1,9

REACTIONS $-

ASAS

# coodempatfin of efter denied Bfne enodate

CRetormaiskg age) oth aldebyrlea / Ketones,
do ghe cormapocdiog P-bndvoeyeatens

Ay ud Bu

Re

24 ok. &-teloeater)

5. yn enoJate ( Reformisty weagent) ome.
generated ba addíAlon og am d-taloenden
a THE, DME, Edo / Toukene sto om adtuoded

¿Aoc puth af amen couple (= ame obtatınd

y veductton of 2foc valide est K/k.

Lux oaddadive e

—— O Eo

Ca ROA
+

ame
, Srolsie

Et (Es go Xx

se (
exolate | pu an
wegen

CE Jae a

2 Te ompgeo of the pm Pu coowdirake
do the are of veforwotaky reagent & results
fa athe, formation of we carbon asco ond.

6. xx The warten proceeds Shuough aa rx |
Ao State . :

Rx

We a "7 &

# Reformatsky emotes awe Jess wave &
hemce -~nusleophthfe addition de She Ester

gree does wet, ous.

» Reformateky seacifons are: often conducted

with extreme Wedezed Ketones

JS ne
+ as

es 4,

ù
e A o ie oc
= cre

pra we

7. ep ES
qian 4169, Seren & SRL wepomited tot il
gretment of a ZPre- topper comple With
Affedowattame Pr Elo producer a reagent
grat adas to alkenes o form edo prepare
ms Sa um 02 Seron — Sth weastfon ,

& &

a Ry

y Me Teautfon grocceds Rough hoc cord |
Getermedtate Tre. Todomethyl Zee Fodide

204%, +220 —y 2 Ta, ear

(INS fodsde) t
> |
\

(Ta) en + eT

Mechantarn $

pl eatdattwe - odds of Ema Ho MT,

#
1
+ Bm. ——> ES

=
Can-caatberofat)

8. a Step-2t- Dioe-canbenofd adda to alker

fa Concerted SteweoSpeckfte Sm
addition ato form buttery Are TS

TRE
ee
wr tPA P|
Gublesply ike
TS
Siep- St Finally cyclopropane 98 Fowwed

301

altere

9. fre Cartbernofd “weak wth, move muclenghüße
double bond Fo denen E poduemes. ;

OL. => CR,

FA

yace ment paeweopelective: ot
7 ecdowed ~oudleopitlfe double bord

A p+ Ob

CT,

major or
4 steseoselektytty RL be vevessed PE my
chelateeg group COR, où, ere) ame present
meer o double band. uelopeepanatten occur
quen abe perme face og double bohd as thet
ef the chelokèg PR

oR

10. x Redfern eshth compounds contaba ade
eae

x Dlalkylzine compounds meat wth compounds

bowing aseo hyerageos do fowen hy drrocartoso

ond behave as base |

> The autd- bage roca af data Loc Jokes
place ho duo Bragas.
saga Rn + A ROA + RH
Sdoge-2 %- “Rena + AH ——e RH + Bn

AM => HOM, Rov, AVON, ResoM, RAMs,
Rezo y ROM,

x SH GR often poppfble do Atop sthe weacilon ot
whe fr adage A obtate he Fatermedtoee
Ran! , | i

R¿2o + MO ——— Remo + RA

gan + on ——— Ring + RH
Rode + Mycol > Renooeny + RH

2204 Rusa ——_sRemceck + RH

11. y OTM DPre weagents eat Bounty AD |
cadeau compounds. Ready of Jae
dtokyztae YB Tove Atom Mar of aber
ALK pL Zire Teagents

ou
j

er
Mg cto + an Ss HES as
a Er "

(er)

+ Tamal

y caste carton bond fovedting cross coupling
mouton of ao balede and an ongam

Ze holíde m pu of ni/pd catalyst

$5 Krocon as Neg coupling
ER]

Ry à Renz A y
ee,

R= aeg, ama, dy, beng?

Re rent, Aye) ory, AA

12. ï
Ber

ve
E

À

ry

ES
1

ne
==
£
1
de

CS
a eT > En,
be! \ ey ge

am, N
2 Rx

# The polladkum-catulyser coupling of orgamo

Foc compound th cthfoeaes do foro

Ketome B Known as Fukuyama coupling.

e
Ru + den eme, a Kui

“Bulene