Ozenoxacin.pptx.pptx

Pharmaceutical chemistry

1. Pharmaceutical Chemistry Prepare by : najem ambarek abd-alhady
Abd-alaziz mahamed moftah

2. Ozenoxacin Trade name: Xepi

3. This Drug prepare in 12/11/2017

4. What is xepi . Introduction Molecular weight and molecular formula and dosage form . General information about ozenoxacin Chemical structure with IUBAC Name Structure of ozenoxacin Structure activity relationship. SAR Mechanism of action 01 02 03 04 05 Presentation content

5. What is Xepi (ozenoxacin) Ozenoxacin cream is indicated for the topical treatment of impetigo caused by Staphylococcus aureus or Streptococcus pyogenes in patients aged 2 months of age and older . Introduction

6. impetigo

7. General information about ozenoxacin 363.4 g/mol Molecular weight C21H21N3O3 Molecular formula Cream Dosage form T reatment of impetigo Treatment

8. Chemical structure IUPAC name 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)pyridin-3-yl]-4-oxoquinoline-3-carboxylic acid

9. Structure activity relationship

10. Mechanism of action Ozenoxacin is a quinolone antibiotic drug. And, like most quinolones, ozenoxacin predominately executes its mechanism of action by entering into bacterial cells and acting to inhibit the bacterial DNA replication enzymes DNA gyrase A and topoisomerase IV

11. THANK YOU For listening