pathology Prepared By: Sana Usmani Department- O.B.G College- TPCON , Teerthanker Mahaveer University
INTRODUCTION Pathology- The word ‘Pathology’ is derived from two Greek words—pathos (meaning suffering) and logos (meaning study). Pathology is, thus, scientific study of changes in the structure and function of the body in disease. In other words, pathology consists of the abnormalities in normal anatomy (including histology) and normal physiology owing to disease. Another commonly used term with reference to study of diseases is ‘pathophysiology’ ( patho =suffering, physiology=study of normal function). Pathophysiology, thus, includes study of disordered function (i.e. physiological changes) and breakdown of homeostasis in diseases (i.e. biochemical changes).
Definition of pathology The study of the essential nature of disease, disease processes, and the structural and functional changes in organs and tissues that cause or are caused by disease. The study of the gross and microscopic patterns of disease.
Common terms in pathology Patient is the person affected by disease. Lesions are the characteristic changes in tissues and cells produced by disease in an individual or experimental animal. Pathologic changes or morphology consist of examination of diseased tissues. These can be recognized with the naked eye (gross or macroscopic changes) or studied by microscopic examination of tissues. Causal factors responsible for the lesions are included in etiology of disease (i.e. ‘why’ of disease). Mechanism by which the lesions are produced is termed pathogenesis of disease (i.e. ‘how’ of disease).
Common terms in pathology Morphology- It is the study of structural changes in disease (gross and microscopic) Clinical significance of the morphologic and functional changes together with results of other investigations help to arrive at an answer to what is wrong (diagnosis), what is going to happen (prognosis), what can be done about it (treatment), and finally what should be done to avoid complications and spread (prevention) (i.e. ‘what’ of disease). Pathogenesis- sequence and patterns of cellular injury that lead to disease
Diagrammatic depiction of disease and various terms used in pathology.
ETIOLOGY OF PATHOLOGY Genetic Acquired (Environmental factors)
GENETIC FACTORS AGE GENES
ENVIROMENTAL AGENTS PHYSICAL CHEMICAL NUTRITION INFECTIONS IMMUNOLOGICAL PSYCHOLOGICAL
Medical pathology It is divided into two parts- General Pathology- General pathology is a broad and complex scientific field which seeks to understand the mechanisms of injury to cells and tissues, as well as the body's means of responding to and repairing injury . Areas of study include cellular adaptation to injury, necrosis, inflammation, wound healing and neoplasia. e.g.,- Common Inflammation, Cancer, Ageing Systemic Pathology- Specific changes in organs e.g.,- goiter, pneumonia, breast cancer
Clinical pathology Definition- It is a medical specialty that is concerned with diagnosis of disease based on laboratory analysis of bodily fluids such as blood and urine, using tools of chemistry, microbiology, hematology and molecular pathology. Histopathology- I nvestigation and diagnosis of disease from examination of tissues. Cytopathology- I nvestigation and diagnosis of disease from the examination of isolated cells
Importance of pathology General knowledge of how disease are caused. General patterns and classification of diseases Evolution of disease from its causes to clinical presentation The signs and symptoms of disease Nature, spread and precautions to prevent common diseases Know the different disciplines that make up pathology Better understand the patient and his disease.
Importance of pathology IN NURSING •Nurses today are not merely restricted to providing bedside care to sick and injured hospitalized patients; they have more challenging expansions and extensions of their role in health care delivery system. •The study of pathology will prepare the nurses to understand how the disease started, what was the main cause of disease process, how diseases are diagnosed and what changes may be expected at cellular, tissue and organ level during the illness.
IMPORTANCE OF PATHOLOGY IN NURSING The significance of studying pathology as a separate subject by nurses is discussed below: 1. Understanding the causes of disease: The knowledge of pathology will equip the nurses with following essential information related to etiology and pathogenesis of diseases: To understand the patterns and classification of diseases Understanding the basic nature of diseases such as inflammatory, degenerative, hemodynamic, infective, autoimmune and neoplastic To understand the etiology and pathophysiological mechanisms, which underlie a disease process To familiarize the nurses with various diagnostic tests and the terminologies used in pathological reports.
IMPORTANCE OF PATHOLOGY IN NURSING 2. Knowledge about Progression of the Disease : The knowledge of pathology helps the nurses to understand the basic structural and functional changes that occur in tissues, organs and the body as a whole. Furthermore, knowledge of pathology helps the nurses: To understand the morphological changes, which take place in the body during various disease processes. To appraise the evolution of disease from its causes to the clinical presentation including signs and symptoms of diseases. To correlate the clinical features with the structural and functional pathological alterations in the organs due to the disease process. Pathology serves as a foundation for nurses to understand the pathophysiology of a disease, so that nursing care can be planned more efficiently.
IMPORTANCE OF PATHOLOGY IN NURSING 3. Early and Effective Diagnosis of Disorders : The clinical manifestations of several diseases may be similar, but the treatment of these conditions may vary considerably. There are numerous pathological tests available and the healthcare provider needs to have a sound knowledge of pathology so as to order the most relevant test to diagnose the condition correctly. 4. Prevention of Disease Condition : There are several routine screening tests, which assist the healthcare providers to diagnose a disease in the initial stages and therefore take the preventive measures. For example FNAC for Breast lumps. 5. Helps in Effective Management and Care of Patients: The knowledge of pathology helps the nurses to understand the ongoing health status of patient; and to assess whether the patient is responding to treatment, by monitoring a series of pathological laboratory results.
REFERENCES BOOK- Mohan Harsh. 2015. Textbook of PATHOLOGY. Seventh Edition. Jaypee Brothers Medical Publishers (P) Ltd. WEBSITE- https://peoria.medicine.uic.edu/departments/hse-pathology/introduction-to-pathology/