Peptic ulcer disease

Pathogenesis and Morphology

1. PEPTIC ULCER DISEASE AADARSH BHADEL 2 ND YEAR, MBBS DMCRI

2. INTRODUCTION Peptic ulcer are the area of degeneration and necrosis of gastrointestinal mucosa exposed to acid-peptic secretions.[Harsh Mohan]

3. Site of occurrence

4. Etiology

5. PATHOGENESIS

6. How H.pylori causes PUD??

7. How NSAIDS and Corticosteroids causes PUD???

8. MORPHOLOGY

9. GROSS Solitary Small (1-2.5 cm in diameter) Round to Oval Sharply punched out lesion

10. MICROSCOPIC

11. REFERENCES Robbins Basic Pathology (9th Edition) Harsh Mohan - Textbook of Pathology, 6th Edition Guyton and Hall Textbook of Medical Physiology (12th Edition)

12. THANK YOU

13. Name: Barry Marshall Known for: H. pylori Award: Noble prize in physiology and medicine