pharmacokinetics crunch.pptx.pdf course work.

coursework,

1. Psychpharmachology
and neuropsychology

2. PHARMACOKINETICS
•ABSORPTION
•DISTRIBUTION
•MATABOLISM
•EXCRETION

4. PHARMACOKINETICS
•PHARMACOKINETICS IS THE STUDY OF DRUGS MOVEMENT IN , THROUGH, AND OUT OF BODY.
•PHARMACOKINETICS IS THE STUDY OF DRUG DISPOSITION IN BODY( THAT WHAT THE BODY DOES TO A
DRUG).
•IT DESCRIBES THAT HOW BODY PROCESS A DRUG.
•ACTIVITY OF DRUG IN BODY.
•ABSORPTION, DISTRIBUTION, LOCALIZATION, EXCRETION.

5. PROPERTIES OF PHARMACOKINETICS
•ABSORPTION
•DISTRIBUTION
•MATABOLISM
•EXCRETION

6. ABSORPTION
•ROUTES OF DRUG ABSORPTION.
•ADVANTAGES AND DISADVANTAGES OF ROUTES.
•MACHANISM OF ABSORPTION
•TRAVELS FROM SITE OF ADMINISTRATION TO SYSTEMATIC CIRCULATION.

7. DISTRIBUTION
•DISTRIBUTION TO THE DIFFERENT ORGANS AND TISSUES .
•DISTRIBUTION DEPENDS ON BLOOD FLOW.
•BLOOD BRAIN BARRIER ( OBSTACLES ) PREVENT THA DRUG TO ENTER THE SPESIFIC ORGANS OR TISSUES.
•DISTRIBUTION IS GOOD THROUGH INTRAVENOUS ROUTE AS IT ENTERS DIRECTLY TO BLOOD STREAM.

8. MATABOLISM
•ACTIVE THE INACTIVE DRUGZ
•BREAK DOWN THE DRUG IN ACTIVE FORM
•INCREASES ABSORPTION RATE
•DECREASES TOXICITY
•INCREASES CHEMICAL STABILITY
•PROLONGED AND SHORTENED THE ACTION

9. EXCRETION
•DRUG ELIMINATE THROUGH EXCRETION
•EXCRETION BY (KIDNEY,LIVER,SKIN)
•KIDNEY IS COMMON PATHWAY
•RENAL DYSFUNCTION
•DRUG ACCUMULATION
•TOXICITY

10. ROUTES OF DRUG ADMINISTRATION
THERE ARE MANY ROUTES OF ADMINISTRATION
I WILL DISCUSS ONLY FIVE ROUTES.
•ORAL
•INTRAVENOUS
•INTRAMUSCULAR
•INHILATION
•CUTANEOUS