SEMINAR ON
POLYMER IN PHARMACEUTICS
R.C.PATEL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH SHIRPUR.
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Presented by: Roshan G Bodhe
M. Pharm I sem
Roll no : 2
Department of pharmaceutics
CONTENT
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1)Introduction
2)Classification of polymer
3)Properties of polymer
4)Characteristics of ideal
polymer
5)Advantages of polymer
6)Application of polymer
7)References
INTRODUCTION
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Polymer is coined from to Greek word “poly” means many
“mer” means parts.
Defination: polymer is defined as very large molecules
having high molecular mass which are formed by joining
of repeating structural unit on large scale.
Monomer : repeating structural unit derived from some
simple and reactive moleculeles are linked to each other
by covalent bond.
Polymerization : process of polymer formation.
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Should be inert and compatible with
environment
Should be non toxic
Should be easily administered
Should have good mechanical strength
Should be biodegradable and
biocompatible
Characteristics of ideal
polymer
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Advantages of polymer
Localised delivery of drug
Sustained delivery of drug
Decrease in dosing frequency
Reduce side effect
Improve patient compliance
Biodegradable and biocompatible
Disadvantages of
polymer
Exhibit dose dumping effect
High initial drug release after administration
Low mechanical properties
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Applications
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POLYMER APPLICATION
Polyethylene oxide Cosmetic pharmaceuticals
Polyethylene glycol Swelling agent
PVP Tablet granulation
Polyvinyl alcohol Tablet binder and coating
Ethyl cellulose Sustained release system
Carboxy methyl cellulose Super disintegrant
HPMC Coating and binder
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Application in Drug delivery system
In modified drug release delivery system
Controlled release formulation
Sustained release formulation
Biomedical applications
Tissue engineering
Bone fixation devices
Vaascular graft
Surgical adhesive