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bansariakbari2298 7 views 1 slides Sep 17, 2024
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-INVERTED PAPILLOMA (TRANSITIONAL CELL PAPILLOMA OR RINGERTZ TUMOUR OR SCHNEIDERIAN PAPILLOMAIP is a tumour of the nonolfactory mucosa of nose (schneiderian membrane ) and paranasal sinuses .Their characteristic inverted mucosal surface extending into of stroma of the papilloma leads to the term inverted for these lesions .They are locally aggressive, have a tendency to recur and are associated with malignancy. Histologically, the tumour is characterized by epithelium inverting into the stroma with a distinct and intact basement membrane. Human papilloma virus has been implicated particularly HPV types 6, 11, 16 and 18.Three histologically types of Schneiderian papillomas were identified as exophytic (everted),inverted, and oncocytic (columnar, or cylindrical cell) papillomas.The commonest sites of origin are the ethmoid region (48%), lateral nasal wall and maxillary sinus (28%) with the frontal sinus accounting for only 2.5%. Most common site of origin is lateral wall of nose in the middle meatus ,less commonly it arises from maxillary ,frontal or sphenoid sinus .Clinically men are affected more than women (3:1)in the age group of 40-70. Incidence of approx 1 per 100000 .it is almost always unilateral and presents with nasal obstruction,nasal discharge and epistaxis . Orbital involvement causes proptosis ,diplopia and lacrimation.physical examination reveals unilateral polypoidal mass from the lateral wall of nose . Grossly it tends to have friable appearance and often bleeds with manipulation.Endoscopic examination reveals typically an irregular translucent fleshy lesion arising from nasal mucosa .Although CT is the primary mode of imaging, MRI is complementary and recommended. Particularly in the frontal sinus when tumour can obstruct the outflow tract, MRI is very useful in distinguishing mucus from papilloma.The commonest sites of origin are the ethmoid region (48%), lateral nasal wall and maxillary sinus (28%) with the frontal sinus accounting for only 2.5%. Most common site of origin is lateral wall of nose in the middle meatus ,less commonly it arises from maxillary ,frontal or sphenoid sinus .Clinically men are affected more than women (3:1)in the age group of 40-70. Incidence of approx 1 per 100000 .it is almost always unilateral and presents with nasal obstruction,nasal discharge and epistaxis . Orbital involvement causes proptosis ,diplopia and lacrimation.physical examination reveals unilateral polypoidal mass from the lateral wall of nose . Grossly it tends to have friable appearance and often bleeds with manipulation.Endoscopic examination reveals typically an irregular fleshy lesion arising from nasal mucosa .Although CT is the primary mode of imaging, MRI is complementary and recommended. Particularly in the frontal sinus when tumour can obstruct the outflow tract, MRI is very useful in distinguishing mucus from papilloma.
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