Promethazine Hydrochloridemedicinet.pptx

center outlines the different types of diabetes, provides information on how diabetes is diagnosed and treated and lists complications that can occur in association with the disease.

Gastro Center
Gastroesophageal Reflux Disease (GERD) is a condition resulting from stomach acid moving backward from the stomach into the esophagus (the tube that connects the mouth to the stomach). The acid causes heartburn and can eventually damage the lining of the esophagus causing inflammation and pain. This center lists drugs available for the treatment of GERD and also describes treatment options for Crohn's disease and Peptic ulcers.

Hair Loss
Hair loss is related to the tendency of hair follicles to stop producing hair growth. This center describes the treatments available for reducing the rate of hair loss.

Menopause
Menopause is the transition period in a woman's life when her ovaries stop producing eggs, her body produces less estrogen and progesterone, and menstruation becomes less frequent, eventually stopping altogether. This center describes the causes, symptoms and treatments available for menopause.

1. Promethazine Hydrochloride By- S tavan Wilson Satpute II year, III Semester

2. Introduction Promethazine is used to relieve or prevent the symptoms of hay fever, allergic conjunctivitis (inflammation of the eye), and other types of allergy or allergic reactions. 2

3. Primarily Used F or Allergy Relief: Treats allergic reactions such rhinitis and urticarial. Nausea and Vomiting: Effective in preventing motion sickness and treating nausea. S edation : Used as a sedaitive or sleep aid. Pereoperative Sedation: Often administered before surgery to help relax patients. 3

4. Mode O f Action 4

5. Pregnancy 5 Category-C Platelet aggregation may be inhibited in newborns following maternal use of promethazine within 2 weeks of delivery . Excretion in breast milk is unknown, the decision to discontinue breast feeling or the drug should be made while taking into account the importance of treatment to the mother .

6. Interactions 6 Central Nervous System Depressants Promethazine may enhance the effects of central nervous system depressants, such as alcohol, benzodiazepines, and opioids . Anticholinergics Combining promethazine with anticholinergics can lead to increased anticholinergic effects, such as dry mouth and constipation . Monoamine Oxidase Inhibitors Promethazine can interact with monoamine oxidase inhibitors, Increasing the risk of adverse effects .

7. Contraindications 7 Hypersensitivity reaction to Promethazine other phenothiazines , or any component of the formation Coma Treatment of lower respiratory tract Symptoms including asthma Intra- a rterial administration

8. Adverse Drug Effects 8 Nervous System : Abnormal sensory Symptoms, agitation, catatonia, confusion, delirium, disorientation, fatigue, insomnia, sedated state and seizure . Cardio vascular : Bready cardia, decreased blood pressure, increased blood pressure, local Thrombophlebitis, venous Thrombosis . Gastrointestinal : Nausea, vomiting . Hematologic: Immune Thrombocytopnia , leukopenia.

9. Nurses Responsibility 9 IM is the preferred route of parenteral administration, administered into deep muscle preparation is not meant for other administration. IV use should be avoided when possible, since severe tissue damage may occur with Iv . Advise patient to increase dietary intake of riboflavin . Advise patient to avoid prolonged exposure to sunlight. use of promethazine in patients with compromised respiratory function should be avoided

10. Thank You