REGENERATIVE ENDODONTICS- oral endodontics

Regenerative endodontic procedures is defined as biologically based procedures designed to replace damaged structures such as dentin, root structures, and cells of the pulp-dentin complex. This new treatment modality aims to promote normal function of the pulp. It has become an alternative to heal apical periodontitis.

1. REGENERATIVE ENDODONTICS

2. WHAT ? REPs are the biologically based   procedures designed to replace the damaged p ulp -dentin complex REPs involve disinfection of the root canal system

3. GOALS OF REP Elimination of symptoms and evidence of bony healing Positive response to vitality testing Increase root wall thickness and/ or increased root length Primary goal Secondary goal Tertiary goal

4. COMPONENTS OF REGENERATIVE ENDODONTICS Undifferentiated cells that are capable of differentiating into various specialised cell types. It can be pluripotent or multipotent in nature. Act as signals to induce cellular proliferation and/or differentiation . 3 Dimensional Structure that contains growth factors. It supports cell organization and vascularization STEM CELLS GROWTH FACTORS SCAFFOLD Stem cells of the apical papilla Dental pulp stem cells Dental follicle stem cells Stem cells from human exfoliated deciduous teeth  Bone morphogenetic protein, transforming growth factor-beta, fibroblastic growth factor, platelet-derived growth factor Collagen Platelet Rich Plasma Polylactic Acid Polyglycolic Acid

5. INDICATIONS CONTRAINDICATIONS Teeth with necrotic pulp and an immature apex in young patients. Good patient compliance Good Periodontal Status Patient with no bleeding or clotting disorders Avulsed Teeth immediately after replantation Inadequate Tooth isolation Teeth that require restoration with a post. Medically compromised patients.