Serum_Sickness_Slide for education .pptx

Serum snakes

1. Serum Sickness in Snake Bite Treatment 🧬 What is Serum Sickness? - Type III hypersensitivity reaction due to immune complex deposition. - Occurs 5–14 days after exposure to non-human proteins (e.g., antivenom). ⚠️ Symptoms: - Fever, rash, joint pain, swollen lymph nodes, fatigue, itching. - Kidney involvement: proteinuria, hematuria. 🧪 Diagnosis: - History of antivenom use, elevated ESR/CRP, eosinophilia, low complement. 💊 Treatment: - Antihistamines, NSAIDs, corticosteroids for severe cases. - Avoid re-exposure to triggering agent. 📋 Monitoring: - Watch for delayed reactions post-antivenom administration.