Sesquiterpenes-Isolation and Applications.pptx

Presentation slides on Sesquiterpenes, a terpene Derivatives Isolation and Applications .

1. SESQUITERPINE s By , Navanidhan.M I M.Sc,Biotechnology Kongunadu Arts and Science College, Coimbatore, Tamilnadu

2. 2 WHAT ARE SESQUITERPENES? ( C 15 H 18 O 3 ) They are Terpenes. ( C 15 H 24 ) Contain Hydrogen and Carbon which makes them Organic compound. They are C15 terpenoids, contains 3 isoprene units. 2D - Structure Model Artemisin ( C 15 H 18 O 4 )

3. 3 Major sesquiterpenes found in  Psidium  species.

4. 4 EXTRACTION, SEPARATION, ISOLATION, PURIFICATION, AND DETERMINATION

5. EXTRACTION TRADITIONAL MODERN MARCERATION HYDRODISTILATION PLE SOLVENT SOXHLET SUPER CRITICAL CO2 UAE SFE MWHD

6. 6 SCHEME OF GENERAL WORKFLOW FOLLOWED IN TERPENES AND TERPENOIDS ANALYSIS ON FOUR IMPORTANT STEPS.

7. 7 The methods for extraction, separation, isolation, purification, and determination of the structural compounds of terpenes and terpenoids.

8. APPLICATIONS 8

9. 9 The potential benefits of terpenes and terpenoids found in EOs.

10. 10 Major sesquiterpenes in essential oils

11. 11 HINOKITOL PHARMACEUTICALS COSMETIC Anti-Cancer -Inhibits A549 cells . Plants, Soaps Etce ., - quenches free radicals Anti-Oxidant - From the woods of Cupracea . Widely used in  cosmetics, clinic products and other areas.

12. 12 CARVACROL Isolated from Origanum vulgare

13. 13 LIMONENE Isolated from Citrus. Anti- Microbial ,Anti -Oxidant etc., Has greater effects with Gentamycin Antibiotics. Inhibition of Gram (+ ve ) S.aureus and Gram (- ve ) E.coli and several Resistant bacteria’s

14. MYRCENE Inhibit the Over production of Pro-Inflammatory Cytokines. Upregulation of Endogenous AO’s and GSH. 14 Found in South African Adenandra villosa . Anti- Inflammatory ,Anti -Microbial, Anti-Catabolic. Also usewd to traet Diabetes, Diarrhoea, Dysentry and Hypertension.

15. 15 ANTI-INFLAMMATORY

16. CITRONELOL 16 Component from Geranium. Used  as a component of many fragrances and food flavourings for its floral-citrus notes. Anti-Allergic. Inhibits the Degranulation of Mast cells and the IgE induced TNF- α production.

17. REFERENCES Fan M, Yuan S, Li L, Zheng J, Zhao D, Wang C, Wang H, Liu X, Liu J. Application of Terpenoid Compounds in Food and Pharmaceutical Products.  Fermentation . 2023; 9(2):119. Abdallah, Ingy & Quax , Wim. (2017). A Glimpse into the Biosynthesis of Terpenoids. KnE Life Sciences. 2017. 81-98. 10.18502/kls.v3i5.981. Wojtunik-Kulesza , Karolina & Kasprzak , Kamila & Oniszczuk , Tomasz & Oniszczuk , Anna. (2019). Natural Monoterpenes: Much More than Only a Scent. Chemistry & Biodiversity. 16. 10.1002/cbdv.201900434. Moujir L, Callies O, Sousa PMC, Sharopov F, Seca AML. Applications of Sesquiterpene Lactones: A Review of Some Potential Success Cases.  Applied Sciences . 2020; 10(9):3001 17

18. 18 THANK YOU