Single Drug (RAJAT & LOHA BHASMA) – Different ANUPANA indicated in Different.pptx

Concept Overview:

Bhasma – calcined metallic/herbo-metallic preparations used in Rasashastra.
Anupana – the suitable vehicle or medium given along with medicine.
It modifies absorption, potency, and therapeutic direction of the drug.

The same Bhasma acts differently when given with different Anupana according to Dosha, Roga, and Rogi Bala.
Proper selection of Anupana enhances the therapeutic potential of Rajata and Loha Bhasma.
The same drug acts in different ways depending on its Anupana.
Understanding this principle is crucial for effective and safe Ayurvedic management of various diseases

1. Single Drug – BHASMA Different ANUPANA indicated in Different DISEASES Dr MAMTA KOLTE 2 nd yr PG Scholar Dept of RS&BK

2. INTRODUCTION Bhasma refers to the calcined metallic/mineral preparations used in Rasashastra for therapeutic purposes. Subjecting metals/minerals to purification & incineration processes to convert them into a fine, bioavailable form. Anupana - the vehicle/adjuvant given with or after medicine to enhance absorption, potency, & targeted action. Bhasma may exhibit different pharmacological actions when administered with different Anupanas . Selection of Anupana depends on disease condition, Dosha predominance, & desired therapeutic effect. 13-10-2025 By- Dr Mamta Kolte 2

3. Definition of MARANA शोधितान् लोहधात्वादीं विमर्ध स्वरसादिभीः । अग्निसंयोगतो भस्मीकरणं मारणं स्मृतम् ।। The process of subjecting the metallic and mineral drugs for different pharmaceutical procedures using a wide range of herbal formulation ( swarasa , kwatha , etc ) and later subjecting them to intense heat to obtain them in the form of Bhasma is called Marana ( incineration ). 13-10-2025 By- Dr Mamta Kolte 3

4. CHARACTERIZATION OF BHASMA Color ( Varna ): A specific color is mentioned for each  Bhasma . The color of the preparation primarily depends on the parent material Lusterless ( Nishchandratvam ):  Bhasma  must be lusterless before therapeutic application. For this test,  Bhasma  is observed under bright sunlight to determine whether luster is present are not, if luster is still present, it indicates further incineration. Lightness and Fineness ( Varitara ):  floats on stagnant water surface. This test is based on the law of surface tension. Properly incinerated  Bhasma  needs to float on the water surface Tactile sensation: Tactile sensation can be absorbed and assimilated in the body without producing any irritation to mucous membrane of gastrointestinal tract Particle size: Prepared  Bhasma  should be in powder form. Particle of  Bhasma  should be like pollen grains of ketaki  flower. 13-10-2025 By- Dr Mamta Kolte 4

5. CHEMICAL CHARACTERISTIC Apunarbhavata : It means the incapability to regain the original metallic form. For this test,  Bhasma  is mixed with an equal quantity of seeds of  Gunja , honey, ghee, and borax, then sealed in earthen pots and heated with a similar grade of heat. Thereafter particular  Bhasma  is observed on self-cooling. Niruttha : To test the inability to regain the metallic form of metallic  Bhasma . In this test,  Bhasma  is mixed with a fixed weight of silver leaf and kept in sealed earthen pots. Then, a similar grade of heat is applied, and after self-cooling, the weight of the silver is taken. An increase in the weight of the silver leaf indicates improperly prepared  Bhasma. 13-10-2025 By- Dr Mamta Kolte 5

6. QUALITY CONTROL OF BHASMA Lusterless: There should be no  chandrika  or metallic luster ( nischandrika ) Rekhapurnatvam : When a  Bhasma  is spread between the index finger and thumb and rubbed, it should be so fine as to get easily into the lines and crevices of the fingers and should not be washed out from the lines of the fingers Varitaratavam : When a small quantity is spread on cold and still water, it should float on the surface Apurnabhava : The  Bhasma  should not revert to the original state Taste:  Bhasma  should be tasteless Avami : The  Bhasma  should not produce nausea on administration. 13-10-2025 By- Dr Mamta Kolte 6

7. IMPORTANCE OF BHASMA Maintain optimum alkalinity for optimum health Provide easily absorbed and usable calcium Cleanse the kidneys, intestines, and liver Maintain stronger bones and healthier teeth Alleviate insomnia, depression Keeps the rhythmic heart beating Keeps arrhythmias and mineral balance Help metabolize iron in the body Aid the nervous system Breakdown heavy metals and drug residues in the body Neutralize harmful acids that lead to illness Protect the body from free radical damage 13-10-2025 By- Dr Mamta Kolte 7

8. Concept of Bhasma with Different Anupana It can enhance or direct specific therapeutic actions. Different Anupanas help pacify specific Doshas. To improve Absorption & Bioavailability. To reduce toxicity To suit diseases & patient condition 13-10-2025 By- Dr Mamta Kolte 8

9. 1) RAJATA BHASMA (Ag) Chemical & Physical Properties: Latin Name Argentinum Symbol Ag Atomic No. 47 Hardness 2.5 to 3 Specific Gravity 10.4 Lustre Reflects 95% of the light rays, make it the most lustrous metal Malleability Most malleable & ductile of all the metals Conductivity Highest conductor of heat & electricity of all metals Melting point 961 C Boiling Point 2193 C Dilution Dilutes in “Nitric acid” (to form silver nitrate) & “ Aquaregia ” (Nitro-hydrochloric acid) 9

10. CHEMICAL ASSAY OF RAJAT BHASMA Silver (as Ag) 55.99 % Iron (as Fe2O3) 14.33% Calcium (as Ca) 10.76% Free Sulphur 0.675% Silver Chloride 0.47% Aluminium Trace Acid Insoluble Ash 19.90% Total Ash Value 94.94% 10

11. PHARMACODYNAMIC PROPERTIES Medhya- Sara & Sukshma guna allows it to cross Manovaha strotasa , nourishing Majja Dhatu. Manas Shamak – Sheeta Virya pacifies Pitta in the mind Rasayana – Acts on Dhatu due to its Laghu, Sukshma & Sara properties, improving metabolism & Ojas. Balya – Enhances Agni & proper nutrient assimilation for Dhatu nourishment. Vrishya (Aphrodisiac) - Provides Rasayana effect in reproductive tissues & nourishes Sukra Dhatu. Medohara ( Antiobesity )- Enhances metabolism via Katu Vipaka , promoting Deepana- Pachana . Jantughna (Antimicrobial) 13-10-2025 By- Dr Mamta Kolte 11

12. PHARMACOKINETIC ACTION ABSORPTION Being in nano/micro particle form, it is easily absorbable through the GI tract The fine particle size & Bhavana enhance bioavailability . Absorption mainly occurs through Sukshma Strotasa & Rasavaha Strotasa 13-10-2025 By- Dr Mamta Kolte 12

13. PHARMACOKINETIC ACTION ABSORPTION Being in nano/micro particle form, it is easily absorbable through the GI tract The fine particle size & Bhavana enhance bioavailability . Absorption mainly occurs through Sukshma Strotasa & Rasavaha Strotasa 13-10-2025 By- Dr Mamta Kolte 13

14. PHARMACOKINETIC ACTION ABSORPTION Being in nano/micro particle form, it is easily absorbable through the GI tract The fine particle size & Bhavana enhance bioavailability . Absorption mainly occurs through Sukshma Strotasa & Rasavaha Strotasa DISTRIBUTION It is distributed through Rasa & Rakta Dhatu to all tissues. Its Sukshma and Sara properties allow it to pass through biological barriers and reach the brain and nervous tissues. Act predominantly on Manovaha strotasa & Majja Dhatu . 13-10-2025 By- Dr Mamta Kolte 14

15. PHARMACOKINETIC ACTION ABSORPTION Being in nano/micro particle form, it is easily absorbable through the GI tract The fine particle size & Bhavana enhance bioavailability . Absorption mainly occurs through Sukshma Strotasa & Rasavaha Strotasa DISTRIBUTION It is distributed through Rasa & Rakta Dhatu to all tissues. Its Sukshma and Sara properties allow it to pass through biological barriers and reach the brain and nervous tissues. Act predominantly on Manovaha strotasa & Majja Dhatu . METABOLISM Supports tissue nourishment ( Dhatu Poshana ) & maintains metabolic stability . EXCRETION Minimal residue due to complete assimilation. Excreted in trace amounts. Non-toxic when prepared properly. 13-10-2025 By- Dr Mamta Kolte 15

16. THERAPEUTIC PROPERTIES रूप्यं विपाकमधुरं तुवराम्लसारं शीतं सरं परमलेखनकं रूप्यम् । स्निग्धं च वातकफजिज्जठराग्निदीपि बल्यं परं स्थिरवयस्करणञ्च मेध्यम् ।। रौप्यं शीतं कषायाम्लं स्निग्धं वातहरं लघु । रसायनविधानेन सर्वरोगापहारकम् । (RRS 5/28-29) 13-10-2025 By- Dr Mamta Kolte 16

17. THERAPEUTIC PROPERTIES रूप्यं विपाकमधुरं तुवराम्लसारं शीतं सरं परमलेखनकं रूप्यम् । स्निग्धं च वातकफजिज्जठराग्निदीपि बल्यं परं स्थिरवयस्करणञ्च मेध्यम् ।। रौप्यं शीतं कषायाम्लं स्निग्धं वातहरं लघु । रसायनविधानेन सर्वरोगापहारकम् । (RRS 5/28-29) तारं मृतं सुशिशिरं तुवरञ्च रुच्यं स्निग्धं विपाकमधुरं परमञ्च मेध्यम् । वर्ण्य परं पवनहारि कफप्रणाशित्वम्लं सरं परमलेखनकञ्च वृष्यम् ।। सुमृतं चन्द्रलोहन्तु वयःस्थापनमुत्तम् । बल्यं परं दाहहरं स्मृतिकान्तिविवर्द्धनम्।। तृष्णाशोषप्रशमनं परमञ्च रसायनम् । भ्रमहारि विशेषेण गर्भाशयविशोधनम् ।। पित्तामयप्रशमनं प्रमेहाद्यामयापहम् । आयुष्यञ्च विशेषेण विष्टब्धाजीर्णनाशनम् ।। मदात्ययात्ययकरं वह्निमान्द्यप्रणाशनम् । विषघ्नं ज्वरहृच्चैव प्लीहोदरविनाशनम् ।। क्षयक्षयकरं नाडीशूलापस्मृतिनुत् परम् । हृद्यं खलु विशेषेण जाठरामयनाशनम् ।। (R.T. 16/46-51) 13-10-2025 By- Dr Mamta Kolte 17

18. AVASTHANUSARA USES AVASTHA PURPOSE/USE ACTION MECHANIM AMAVASTHA Preventive, tissue nourishment Initiate Rasayana , Medhya, Manasa Shamaka action Sukshma & Sara Gunas penetrate weak metabolism & prepare Dhatus for rejuvenation PAKWAVASTHA Therapeutic, curative Balya, Medhya, Vrishya , Shothahara Rasa, Guna, Virya, Vipaka act fully Nanoparticles penetrate tissues for maximum efficacy 13-10-2025 By- Dr Mamta Kolte 18

19. AVASTHANUSARA USES AVASTHA PURPOSE/USE ACTION MECHANIM AMAVASTHA Preventive, tissue nourishment Initiate Rasayana , Medhya, Manasa Shamaka action Sukshma & Sara Gunas penetrate weak metabolism & prepare Dhatus for rejuvenation PAKWAVASTHA Therapeutic, curative Balya, Medhya, Vrishya , Shothahara Rasa, Guna, Virya, Vipaka act fully Nanoparticles penetrate tissues for maximum efficacy DOSHA-WISE ROLE VATA Reduces anxiety, nervous disorders, weakness Sara & Sukshma gunas penetrate Manovaha , Majja Dhatu PITTA Reduces inflammation, burning sensations, and mental agitation Sheeta Virya, Madhura Vipaka cools Pitta, Kashaya Rasa purifies blood KAPHA Reduces obesity, edema , lethargy Lekhna property, Laghu Guna- mobilize fat, enhance metabolism 13-10-2025 By- Dr Mamta Kolte 19

20. Matra, Sevan Kaal, Kaal-Maryada रक्तिकायास्तुरीयांशाद्रक्तिकैकमितं परम् । मृतं तारं नियुञ्जीत बलकालाद्यपेक्षया । ( R.T. 16/54) ¼ (31mgs) – 1 (25mgs) Ratti Sevana Kaal & Kaal-Maryada : Depends on Rogi Bala, Roga Bala 13-10-2025 By- Dr Mamta Kolte 20

21. Various Indications along with Dosage & ANUPANA A/D Ras Tarangini 16/55-75 R.R.S 5/41 Ayurveda sara sangraha भस्मीभूतं रजतममलं तत्समौ व्योमभानू, सर्वैस्तुल्यं त्रिकटुसवरं सारघाज्येन युक्तम्। लीढं प्रातः क्षपयतितरां यक्ष्मपाण्डूदरार्शः, श्वासं कासं नयनजरुजः पित्तरोगानशेषान् (RRS 5/41) 21

22. Various Indications along with Dosage & ANUPANA A/D Ras Tarangini 16/55-75 R.R.S 5/41 Ayurveda sara sangraha भस्मीभूतं रजतममलं तत्समौ व्योमभानू, सर्वैस्तुल्यं त्रिकटुसवरं सारघाज्येन युक्तम्। लीढं प्रातः क्षपयतितरां यक्ष्मपाण्डूदरार्शः, श्वासं कासं नयनजरुजः पित्तरोगानशेषान् (RRS 5/41) Diseases Anupana Koshathagta Vaayu Yavani & devpushap churan Ajiranrogajanit Hridsapandan Ela Churna Suryavarta & Ardhavabhedaka Ela & Mishri Churna Durgandhita strava Rsa sindoora , Shu. Tankana , Haridrea Swarasa-2weeks Grudhrasi , Vishwachi , trikvedana , Nadishula Loha Bhasma, Swarnamakshika Bhasma, Rasa sindoora , Ajamoda & Chitraka Kwatha Shakhagata Pitta Prakoapa Parpataka , Usheera , Dhanyaka , pittaghna kwatha Madatyaya Rajavarta Bhasma Adhmaan Chopchini churna or Kashaya Shakhashrita Daaha Sitapala Unmaad Sita, Ghrita , Ela Prameha Trijataka Churna 22

23. Disease Anupana Sharirik Daaha Mishri 1 Masha + Rajata Bhasma ½ ratti Prakupita Vaat & Pitta Dosha Rajata Bhasma 1 ratti + Abharaka Bhasma 1 ratti + Ela Churna 2 ratti + Madhu Prameha Rajata bhasma 1 ratti + ela churna + daalchini churna + tejpatra churna each 3-3 ratti mixed with shudha shilajit Mastishka Daurbalya Rajata bhasma 1 ratti + praval pishti 1 ratti + smriti sagar rasa 1 ratti + brahmi Swarasa Pandu Rajata bhasma 1 ratti + mandur bhasma 1 ratti + trikatu churan 4 ratti + madhu Sushka Kaasa Rajata bhasma 1 ratti + praval chandarputi 1 ratti + shudha tankana 2 ratti + vasa Swarasa Jwara Rajata bhasma 1 ratti + pippali churna 2 ratti + ela churna 2 ratti 23

24. Disease Anupana Sharirik Daaha Mishri 1 Masha + Rajata Bhasma ½ ratti Prakupita Vaat & Pitta Dosha Rajata Bhasma 1 ratti + Abharaka Bhasma 1 ratti + Ela Churna 2 ratti + Madhu Prameha Rajata bhasma 1 ratti + ela churna + daalchini churna + tejpatra churna each 3-3 ratti mixed with shudha shilajit Mastishka Daurbalya Rajata bhasma 1 ratti + praval pishti 1 ratti + smriti sagar rasa 1 ratti + brahmi Swarasa Pandu Rajata bhasma 1 ratti + mandur bhasma 1 ratti + trikatu churan 4 ratti + madhu Sushka Kaasa Rajata bhasma 1 ratti + praval chandarputi 1 ratti + shudha tankana 2 ratti + vasa Swarasa Jwara Rajata bhasma 1 ratti + pippali churna 2 ratti + ela churna 2 ratti Disease Anupana Udaragata Vaata Rajata bhasma 1 ratti + jeera churna 4 ratti + bhurjit hing 1 ratti + ushnodak jala Vatika Shula Rajata bhasma 1 ratti + vacha churan 1 masha + godugdha Anidra Rajata bhasma 1 ratti + sawaranmakshika bhasma 1 ratti + praval Bhasma 1 Unmaad & Apasmara Rajata bhasma 1 ratti + Vacha churan 3 ratti + Ghrita Snayu Daurbalya ajata bhasma 1 ratti + Bhasma 1 ratti Hikka Rajata bhasma 1 ratti + Amalaki & pippali churan 2-2ratti Netra Roga Rajata bhasma 1 ratti + mulethi churan 4 ratti Amlapitta , Ajirna , Aruchi Rajata Bhasma 1 ratti + Ghrita 24

25. Ashuddha / Apakwa Bhasma Sevanjanya Vyadhi - Shantiupaya आयुः शुक्रं बलं हन्ति तापविड्वन्धरोगकृत्। अशुद्धं न मृतं तारं शुद्धं मार्यमतो बुधैः ।। (RRS 5/39) Ashuddha / Apakwa Bhasma Sevanjanya Vyadhi : Ayu, Sukra, Bala Nasa, Santap, and Vidbandh Shantiupaya : Sharkara With Madhu- 3days 13-10-2025 By- Dr Mamta Kolte 25

26. 2) LOHA BHASMA Chemical & Physical Properties: Latin Name Ferrum Symbol Fe Atomic No. 26 Atomic Weight 55.85 Density 7.874 Melting Point 1535 C Boiling Point 3000 C Conductivity Relatively poor conductor of heat & electricity Dissolution Dissolve in water but process takes many months Atmospheric Exposure Reacts with oxygen & form iron oxide (Fe2O3) Chemical Response Turns into iron salts when exposed to acids. Remains unaffected by alkalies . 26

27. Chemical & Physical Properties: CHEMICAL ASSAY Iron (Fe) 85-95% Ferric Oxide 2-5% Ferrous Oxide 1-3% Trace Elements <1% Organic Residue <1% 27

28. PHARMACODYNAMIC PROPERTIES Balya- Madhura rasa & Madhura Vipaka nourish all Dhatus, especially Rakta & Mamsa . Vrishya - Improve Ojas & Shukra Dhatu formation. Shleshma-Pittaghna - Tikta -Kashaya Rasa & Sheeta Virya pacify both. Rasayana - Madhura Vipaka & Rasayana Prabhava rejuvenate tissues & improve longevity. Dhatuvardhaka - Loha acts as Rakta Dhatu Poshaka ; support Majja , Mamsa & Ojas formation. Agnideepana - Laghu, Tikshan guna enhances Agni, promoting metabolism & digestion. 13-10-2025 By- Dr Mamta Kolte 28

29. PHARMACOKINETIC PROPERTIES ABSORPTION Proper Shodhana and Marana convert metallic iron into a bioavailable, non-toxic form with increased surface area, enhancing absorption. DISTRIBUTION It primarily accumulates in Rakta and Majja Dhatus , promoting hemoglobin synthesis and tissue oxygenation. 13-10-2025 By- Dr Mamta Kolte 29

30. PHARMACOKINETIC PROPERTIES ABSORPTION Proper Shodhana and Marana convert metallic iron into a bioavailable, non-toxic form with increased surface area, enhancing absorption. DISTRIBUTION It primarily accumulates in Rakta and Majja Dhatus , promoting hemoglobin synthesis and tissue oxygenation. METABOLISM Slow release of iron prevents oxidative damage and maintains a steady supply for erythropoiesis. EXCRETION Excess or unabsorbed iron is excreted via bile and feces , with trace amounts in urine and sweat. 13-10-2025 By- Dr Mamta Kolte 30

31. Properties of Loha कान्तं तु शीतं मधुरं कषायमायुष्करं धातु विवर्धनं च। हन्यात्त्रिदोषव्रणमेहकुष्ठप्लीहोदरग्रन्थिविषक्रिमींश्च ।। पाण्डु पीडयति क्षयं क्षपयति क्षैण्यं क्षिणेति क्षणात्कासं नाशयति भ्रमं शमयति श्लेष्मामयान्खादति। असं गुल्मसशूलपीनसवमिश्वासप्रमेहारुचीराशून्मूलयति प्रकम्पनहरं लोहं हिमं चाक्षुषम् ।। शुद्ध पित्तकफानिलमोहं हन्ति हितं शिवशक्त्या लोहम्। पाण्डुगदामयशूलविनाशि प्राक्तमशुद्धं रोगविकासि ।। (RRS 5/55-60) 13-10-2025 By- Dr Mamta Kolte 31

32. Properties of Loha कान्तं तु शीतं मधुरं कषायमायुष्करं धातु विवर्धनं च। हन्यात्त्रिदोषव्रणमेहकुष्ठप्लीहोदरग्रन्थिविषक्रिमींश्च ।। पाण्डु पीडयति क्षयं क्षपयति क्षैण्यं क्षिणेति क्षणात्कासं नाशयति भ्रमं शमयति श्लेष्मामयान्खादति। असं गुल्मसशूलपीनसवमिश्वासप्रमेहारुचीराशून्मूलयति प्रकम्पनहरं लोहं हिमं चाक्षुषम् ।। शुद्ध पित्तकफानिलमोहं हन्ति हितं शिवशक्त्या लोहम्। पाण्डुगदामयशूलविनाशि प्राक्तमशुद्धं रोगविकासि ।। (RRS 5/55-60) लौहं रूक्षं सुमधुरमलं पाकतश्चाथ तिक्तं वीर्ये शीतं गुरु च तुवरं लेखनञ्चातिनेत्र्यम् । बल्यं वृष्यं जठरगदनुत् श्लेष्मपित्तामयघ्नं वण्यं मेध्यं खलु किमधिकं हन्ति नानामयघ्नम् ।। लौहं दीपनमुत्तमं क्षयहरं कुष्ठामयध्वंसकं गुल्मप्लीहविधूननं क्रिमिहरं पाण्ड्वामयघ्नं परम् मेदोमेहनिबर्हणं गदहरं दुर्नामरोगान्तकृत् छर्दिश्वासहरं त्वलं बहुगिरा योगेन नानार्तिनुत् ।। विसर्पकरिकेशरी प्रबलशूलनिर्मूलनः क्षयक्षयकरः परं चिरजशोथं सङ्कोचनः । यकृद्गदविधूननो गुदमहागदेभाङ्कशः परं विजयतेतरां विधिहतस्तु लौहो ह्ययम् ।। स्वास नाशयति क्रिमीन् कृशयति क्षैण्यं क्षिणोति द्रुतं शोषं शोषयति भ्रमं त्वपहरेच्छूलं समुन्मूलयेत्। कासं ह्रासयति क्षयं क्षपयति भ्रान्ति निहन्त्यन्ततः स्थौल्यं विह्वलयत्पलं दलयति श्लेष्मामयान् सर्वथा ।। (RT 20/83-86) 13-10-2025 By- Dr Mamta Kolte 32

33. Properties of Loha कान्तं तु शीतं मधुरं कषायमायुष्करं धातु विवर्धनं च। हन्यात्त्रिदोषव्रणमेहकुष्ठप्लीहोदरग्रन्थिविषक्रिमींश्च ।। पाण्डु पीडयति क्षयं क्षपयति क्षैण्यं क्षिणेति क्षणात्कासं नाशयति भ्रमं शमयति श्लेष्मामयान्खादति। असं गुल्मसशूलपीनसवमिश्वासप्रमेहारुचीराशून्मूलयति प्रकम्पनहरं लोहं हिमं चाक्षुषम् ।। शुद्ध पित्तकफानिलमोहं हन्ति हितं शिवशक्त्या लोहम्। पाण्डुगदामयशूलविनाशि प्राक्तमशुद्धं रोगविकासि ।। (RRS 5/55-60) लौहं रूक्षं सुमधुरमलं पाकतश्चाथ तिक्तं वीर्ये शीतं गुरु च तुवरं लेखनञ्चातिनेत्र्यम् । बल्यं वृष्यं जठरगदनुत् श्लेष्मपित्तामयघ्नं वण्यं मेध्यं खलु किमधिकं हन्ति नानामयघ्नम् ।। लौहं दीपनमुत्तमं क्षयहरं कुष्ठामयध्वंसकं गुल्मप्लीहविधूननं क्रिमिहरं पाण्ड्वामयघ्नं परम् मेदोमेहनिबर्हणं गदहरं दुर्नामरोगान्तकृत् छर्दिश्वासहरं त्वलं बहुगिरा योगेन नानार्तिनुत् ।। विसर्पकरिकेशरी प्रबलशूलनिर्मूलनः क्षयक्षयकरः परं चिरजशोथं सङ्कोचनः । यकृद्गदविधूननो गुदमहागदेभाङ्कशः परं विजयतेतरां विधिहतस्तु लौहो ह्ययम् ।। स्वास नाशयति क्रिमीन् कृशयति क्षैण्यं क्षिणोति द्रुतं शोषं शोषयति भ्रमं त्वपहरेच्छूलं समुन्मूलयेत्। कासं ह्रासयति क्षयं क्षपयति भ्रान्ति निहन्त्यन्ततः स्थौल्यं विह्वलयत्पलं दलयति श्लेष्मामयान् सर्वथा ।। (RT 20/83-86) शाखाश्रितं कोष्ठसमाश्रितं वा पित्तं विवृद्धन्तु मलाभिधेयम् । मृत्तु लौहं शमयेन्नितान्तं यथा समीरः खलु मेघवृन्दम् ।। (RT 20/97) All types of Pittaja roga situated in Shakha and Kostha will be effectively cured by judicious consumption of ' loha bhasma ’. Simile : As the wind drives away the clouds, this ' loha bhasma ' drives away all types of ‘PITTAJA ROGA’. 13-10-2025 By- Dr Mamta Kolte 33

34. AVASTHANUSARA USES Avastha Purpose Action Mechanism Amavastha Not generally indicated; if required, used with Deepana- Pachana dravyas Agnidipana , Ama Pachana . (stimulation of digestion, toxin removal) During Ama stage, Agni is weak and channels are blocked. When combined with Triphala , Madhu helps stimulate Agni, digest Ama, and prepare the body for Dhatu poshana . Pakwavastha Main stage for therapeutic use Rasayana , Balya, Raktavardhaka In Nirama state, channels are open; Bhasma acts directly on Rakta Dhatu , increasing hemoglobin, vitality, and immunity. 13-10-2025 By- Dr Mamta Kolte 34

35. AVASTHANUSARA USES Avastha Purpose Action Mechanism Amavastha Not generally indicated; if required, used with Deepana- Pachana dravyas Agnidipana , Ama Pachana . (stimulation of digestion, toxin removal) During Ama stage, Agni is weak and channels are blocked. When combined with Triphala , Madhu helps stimulate Agni, digest Ama, and prepare the body for Dhatu poshana . Pakwavastha Main stage for therapeutic use Rasayana , Balya, Raktavardhaka In Nirama state, channels are open; Bhasma acts directly on Rakta Dhatu , increasing hemoglobin, vitality, and immunity. Dosha Wise Role Vata To nourish the Dhatus and reduce weakness. Ruksha & Sheeta Gunas of Lauha are balanced by Snigdha Anupāna ( Ghrita , Milk etc.). It strengthens Rakta & Majja Dhatu, stabilizing Vata. Pitta To cool and purify blood, reduce burning & bleeding. Tikta -Kashaya Rasa and Sheeta Veerya pacify Pitta, improve Rakta quality, and alleviate Raktapitta , burning sensation, and inflammation. Kapha To reduce Meda, Kapha, and Kleda ; stimulate digestion. Ruksha, Tikta , and Kashāya Rasa scrape excess Kapha and Meda, improve metabolism (Agni). 13-10-2025 By- Dr Mamta Kolte 35

36. Dosage, Sevan Kaal, Kaal-Maryada Dosage: आरभ्य गुञ्जापादांशात् गुञ्जाद्वितयसंमितम् । मृतं लौहं प्रयुञ्जीत प्राणाचार्यः प्रयत्नतः ।। (RT 20/98) 1/3 Ratti (31mgs) to 2 Ratti (250mgs) वल्लं वल्लार्धमानं च यथायोगेन योजयेत्। (RRS 5/155) Standard dosage: 1 Valla (250mg) or ½ Valla (125mg) Sevan Kaal, Kaal-Maryada: Depends on Roga Bala, Rogi Bala 36

37. DISEASE WISE LOHA ANUPANA त्रिफलामधुसंयुक्तं सर्वरोगेषु योजयेत् । पथ्याशिनामयो भस्म यथोक्तगुणदं भवेत् (Ayu Pra 3/228) Triphala Churna /Kashaya + Madhu + Loha Bhasma = in all disease वल्लं वल्लार्धमानं च यथायोगेन योजयेत्। त्रिफला लोहचूर्णं च वलीपलितनाशनम् ।। व्योष भार्गी च मधुना लोहं धातुरुजापहम्। कज्जलीमधुकृष्णाभ्यां श्लेष्मरोगनिवारणम् ।। शर्करा च चतुर्जातं रक्तपित्तरुजापहम्। पुनर्नवा च गोक्षीरैर्बलवृद्धिकरं परम् ।। पुनर्नवारसेनैव पाण्डुरोगनिषूदनम्। हरिद्रा लोहचूर्णं च पिप्पली मधुना सह ।। विंशतिं च प्रमेहाणां नाशयेन्नात्र संशयः ।। शिलाजतुसमायुक्तं मुत्रकृच्छ्रनिवारणम्। वासकः पिप्पली द्राक्षा लोहं च मधुना सह ।। गुटिकां भक्षयेत्प्रातः पञ्चकासनिवारणम्। ताम्बूलेन समायुक्तं भक्षयेल्लोहमुत्तमम् ।। अग्निदीप्तिकरं वृष्यं देहकान्तिविवर्धनम्। किमत्र बहुनोक्तेन देहलोहकर मतम् ।। (RRS 5/150-158) 13-10-2025 By- Dr Mamta Kolte 37

38. त्रिफलामधुसंयुक्तं सर्वरोगेषु योजयेत् । पथ्याशिनामयो भस्म यथोक्तगुणदं भवेत् (Ayu Pra 3/228) Triphala Churna /Kashaya + Madhu + Loha Bhasma = in all disease DISEASE ANUPANA Vali- Palitya Triphala Churna + loha bhasma Dhaturujapahama Vyosha + Bharangi +Loha Bhasma with Madhu Kapha Vikara Kajjali + Madhu + Pippali Churna + Loha Bhasma Raktapitta Sharkara + Chatirjataka Churna + Loha bhasma Pandu Roga Loha Bhasma + Godugdha + Punarnava Swarasa Prameha Loha Bhasma + Haridra + Pippali + Madhu Mutrakrccha Loha Bhasma + Shilajatu 5 Kasa Vasa + Pippali + Draksha + Madhu (pills prepared with loha Bhasma) Agnidiptikara , Vrishya , Dehakantivardhana Tambula Patra 13-10-2025 By- Dr Mamta Kolte 38

39. 13-10-2025 By- Dr Mamta Kolte 39 A/C to RT 20/88-117

40. Apathya During Loha Bhasma Sevana कूष्माण्डं तिलतैलं च माषान्नं च राजिकां तथा। मद्यमम्लरसं चैव त्यजेन्नोहस्य सेवकः ।। मत्स्यं जीवकवार्ताकमाषं च कारवेल्लकम्। व्यायामं तीक्ष्णकं मद्यं तैलाम्लं दूरतस्त्यजेत् ।। (Y.R 5-6) 13-10-2025 By- Dr Mamta Kolte 40

41. Ashuddha / Apakwa Bhasma Sevanjanya Vyadhi - Shantiupaya अपक्वं लोहजं चूर्णमायुः क्षयकरं नृणाम् ।। (Y. R 169) अशुद्धलोई न हितं निषेवणादायुर्बलं कांति-विनाशि निश्चितम् ॥ हृदि प्रपीडां तनुते ह्यपाटवं रुजं करोत्येव विशोध्य मारयेत् ॥ (RRS 5/146) Ashuddha / Apakwa Bhasma Sevanjanya Vyadhi : Ayu, Bala, Kanti Nasa, Hridyapida (R.R.S.5/146) Shantiupaya : Agastya Swarasa Bhavita Vidanga, along with Agastya Swarasa ( Ay.Pra . 3/230) 13-10-2025 By- Dr Mamta Kolte 41

42. Similarities of Rajata & Kanta Loha ये गुणा मृतरूप्यस्य ते गुणाः कान्तभस्मनः। कान्ताभावे प्रदातव्यं रूपमित्याह भैरवः ।। (Y.R 4) All the qualities & curative properties of Rajata & Loha Bhasma are the same. These can be substituted for each other in case of the non-availability of any one of them 13-10-2025 By- Dr Mamta Kolte 42

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45. COCLUSION The therapeutic effect of Bhasma varies according to the type of Anupana used. Anupana acts as a catalyst, enhancing the absorption, assimilation, & targeted action of Bhasma. The same Bhasma can be utilized in different diseases by changing the Anupana , making it versatile & pt.-specific. Selection of Anupana depends on Dosha, Rogi Bala, Rogavastha , & desired pharmacological effect. A proper combination of Bhasma & suitable Anupana ensures maximum efficiency, safety, & desired therapeutic effect. 13-10-2025 By- Dr Mamta Kolte 45

46. Thank You! 13-10-2025 By- Dr Mamta Kolte 46