INTRODUCTION All surgical wounds are contaminated by bacteria, but only a minority actually demonstrate clinical infection Surgical site infection are not an extinct entity as they account for 3 rd most common hospital infection In Nigeria incidence ranges from 14-27% with highest incidence in north-east( Ahmed et al 2018) making it a major patient safety concern in hospital <1900 – Mortality was about 70-80% >1900- Joseph Lister- brought antiseptic surgery
Definition Definition Of Terms: Contamination- the mere presence of pathogenic microorganism on a surface Colonization- the replication/proliferation of microorganism Infection- the host immune response to the invasion of rapidly replicating microorganism SIRS- systemic manifestation to the presence of infection(has many variables) Sepsis- Documented or suspected infection with some of the findings of SIRS. Has 2 subset( severe sepsis and septic shock)
Surgical Site Infection- Are infection of the tissue ,organ or space exposed during performance of an invasive procedure usually occurring within 30days of the procedure or 1y if with implants. It was a revision in 1992 by CDC from wound infection to prevent confusion
Classification Base on severity
Base on degree of contamination
Base on duration
Types
Pathogenesis
Sources Exogenous Surgeons, nurses and other staffs Medical equipment Other patient Endogenous Skin flora Other infection in patients Blood transfusion
Risk factors Patient factors Microbial factors Local factors
Patients factors age obesity immunosuppression DM malnutrition smoking anemia steroids use
Microbial factor P rolong hospitalization Resistance to clearance(capsule formation) Virulence(toxin secretion)
Local factors E xcessive use of cautery Poor skin preparation B raided sutures Drains/catheters Inadequate antibiotic prophylaxis Hypoxia Hypothermia Contaminated instrument
Wound scoring system
Score 0-10=satisfactory healing 11-20=disturbance of healing 20-30=minor wound infection 31-40= moderate wound infection >41= severe wound infection
Risk assessment SCENIC SCORE -abdominal surgery -operation >2hours - class iii and iv ->3diagnosis at discharge from hospital Risk score od 0=1% ,1=3.6%, 2=9%, 3=17% and 4=27% risk of infection
Investigation Diagnosis is clinical, Investigation helps in treatment and follow up MCS, Tissue biopsy USS FBC+D For underlying conditions e.g DM, foreign body, anastomotic breakdown, fistula formation
Prevention General principles involve maneuvers to Diminish presence of exogenous sources (surgeons, theatre, ward ,other patients) Diminish presence of endogenous sources(patient) antimicrobial, chemically, mechanically etc
Management The precept of mgt differs -Drainage of all purulent material -Debridement of all infected, devitalized tissue and debris -Removal of foreign bodies at site of infection -Antimicrobial agents
Complications Depend on site of infection, nature of surgery and underlying host factor Early -Necrotizing fasciitis -Wound dehiscence -Metastatic abscess - Septisemia -Organ failure Late -Incisional hernia -Deforming scar
SSI is a major problem in surgical practice despite been preventable It is the responsibility of all health care provider to work towards its prevention with a team approach involving the patient, surgeon and hospital management team
Reference Schwartz's principle of surgery chpt6 E.A Badoe Principles and Practice of surgery 4 th ed. Bailey and Love 26 th ed. Chpter 5 pg 51-57 Africa Journals Online, S Afr Fam Vol 56 No2, dept anaesthesia chris hani university of witwatersrand
THANK YOU FOR LISTENING “As to disease, make a habit of two things- To help, Or At least to do no harm” Hippocrates.