SYNTHETIC COORDINATION CHEMISTRYFinal.pptx

interesting topic on synthetic coordination chemistry

1. SYNTHESIS AND STRUCTURAL CHARACTERIZATION OF A MONONUCLEAR ZINC(II) COMPLEX M.Sc SEMESTER (IV) EXAMINATION- 2018 Presented By Taslima Khatun Roll No : BUR CH 2016/084 Regn number : 014893 of 2013-2014 Project Supervisor : Dr. Rajarshi Ghosh

2. Polyphenol oxidase activity : Enzymatic browning of natural foods ( fruits (apricots, pears, bananas, grapes), vegetables (potatoes, mushrooms, lettuce) and also seafood (shrimps, spiny lobsters and crabs)

3. Chemical Reactions Involved Polyphenol Oxidase Polymerization Tyrosinase Tyrosinase/ Catechol Oxidase Cresolase activity Catecholase activity Melanines ½ O 2 ½ O 2 P. Bielicki et al , J. Agric. Food Chem. , 2013 , 61, 276

4. Catechol oxidase: active site structure B. Krebs, Germany Type 3 copper protein First isolated from potatoes in 1937 In the active site, two antiferromagnetically coupled hydroxo bridged Cu(II) centres are 2.9 Å apart Each Cu(II) is linked with histidine ring and forms trigonal bipyramidal geometry B. Krebs et al, Nat. Struct. Biol., 1998 , 108, 1084 B. Krebs et al, Acc. Chem. Res., 2002 , 35, 183

5. Polyphenol oxidase activity : Laboratory investigations 5 Polymerisation Catalyst O 2 O 2 Catalyst

6. Catecholase activity: Some Zn(II) complexes D.Das et al. , Inorg. Chem ., 51 ( 2012) 8750

7. Catecholase activity: Some Zn(II) complexes Biswas et.al Eur. J. Inorg. Chem.(2014) 3350

8. Synthesis of Ligand (L) + EtOH Reflux Characterization of Ligand (L1) The peak at 1625 cm -1 is indicative of the formation of the Schiff base

9. Synthesis of Complex (1) Zn(ClO 4 ) 2. 6 H 2 O + L1 MeOH Complex (2) X- Ray structure of the complex Crystal system: Monoclinic Space group: C 1 c 1

10. Conclusions Synthesis of a mononuclear Zn(II) complex was done The synthesized crystal was X-Ray crystallographically characterized The crystal belonged to monoclinic crystal system with space group C 1 c 1 The crystal is expected to show catecholase like activity Catecholase activity of the synthesized crystal shall be investigated in near future

11. Acknowledgements Our respected HoD Supervisor : Dr. R. Ghosh The University of Burdwan: infrastructural facilities All other Teachers of the department for their valuable suggestions Librarian and Non teaching members of the department for their help