Syrup

liquid dosage form syrup

1. PRESENTED BY: L.GOPI B.Pharm ., AADHI BHAGAWAN COLLEGE OF PHARMACY RANTHAM GUIDED BY: K.Shyamala M.Pharm ., PROF OF DEPARTMENT OF PHARMACEUTICS AADHI BHAGAWAN COLLEGE OF PHARMACY RANTHAM

2. SYRUP It’s a liquid dosage form taken to the oral route. Viscous , concentrated solution of sucrose and other sugars. With ( or ) with out medicaments. Flavouring agent vehicle. Contain up to 85% to resist bacterial growth. Intended for oral use.

3. COMPONENTS Sucrose ( or ) other substitute ( glycogenic or non-glycogenic ) Glycogenic = sorbitol , glycerine , propyl glycol. Non – glycogenic = methyl cellulose , H ydroxy methyl cellulose ( suitable for diapetic partients )

4. COLOURING AGENTS Green = Mint Brown = Chocolate Red = Amaranth

5. DISADVANDAGES : Formation of invert sugar. Effect the taste , stability. glucose + fructose sucrose hydrolysis heat invert sugar form

6. CARAMELIZATION : The product become black color is sucrose is over heat is called as caramelization . The process avoid maintain temperature. sugar = 110˚C galatose = 160˚C glucose = 160˚C maltose = 180˚C saccharose = 160˚C

7. MEDICATED SYRUP CONTAINING A THERAPEUTIC AGENTS Demerol syrup Thorazine syrup Phenergan syrup Lithium citrate syrup Gualfenesin syrup Lpecal syrup

8. Example for other syrup image:

9. CONTAINERS

10. TYPES OF CONTAINERS : Plastic container = colorless , brown color container mostly use other color is available Glass container = colorless , brown color form

11. TYPES OF CORKS :

12. STORAGE: It’s maintain the temperature. stable temperature. completely fill the container . no more air phase in surface of product growth of micro organism. so completely fill the container

13. so not completely fill the container to form microbial organism growth.

14. THANK YOU

15. PREPARED BY : L.GOPI B.Pharm ., THIRD YEAR CREATER 6 PHARMA GROUP 2012 – 2016 ABCP