Thalassemia
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What is Thalassemia?
•Thalassaemiais a genetic disorder which is
inherited from parents.
•The marriage of two Thalassaemiccarriers
could result in the birth of a Thalassaemia
major who requires blood transfusions once a
month or every three weeks in order to stay
alive.
Types of thalassemia
•Beta thalassemia carrier
Beta thalassemia major
Beta thalassemia minor
•Alpha thalassemia carrier
Alpha thalassemia plus
Alpha thalassemia zero
Difference between alpha thalassemia and beta thalassemia
Alphathalasemiaoccurs if there are problems with some or
all of the alph-globin genes.Betathalasemiaoccurs when
there are problems with one or both of thebeta-globin genes
7 facts about thalassemia
•1. Thalassemia is a disorder of the blood
•2. Thalassemia is a hereditary disorder, it is
passed on from parents to children through
the genes
•3. Thalassemia is a haemoglobindisorder
•It is a disorder that doesn’t allow the protein
of the red blood cells to carry enough oxygen
around the body and keep it healthy
•4. Approximately 7% of the global population
is a carrier of a severe haemoglobindisorder,
includinthalassemia
•5. Between 300000 to 500000 children are
born annually with a severe haemoglobin
disorder
•6. About 80% of affected children are born in
middle and low income countries
•7. And most importantly, thalassemia is today
both preventable and treatable!
Status of Thalassemia in the Maldives
It was found that in Maldives, 18% of the population were
affected with this trait with one in every 120 births being a
Thalassaemiamajor.
Treatment…
•Blood Transfusions. Transfusions of red blood
cells are the main treatment for people who
have moderate or severe thalassemia. ...
•Iron Chelation Therapy. The hemoglobin in red
blood cells is an iron-rich protein. ...
•Folic Acid Supplements. ...
•Blood and Marrow Stem Cell Transplant.
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