Chemistry: The Central Science Dr. Retheesh Krishnan Assistant Professor (on deputation) Department of Chemistry Govt. College for Women
Dr. Retheesh Krishnan 2 Sterner- Elser Empirical Molecular Formula H 375000000 O 132000000 C 85700000 N 6430000 Ca 1500000 P 1020000 S 206000 Na 183000 K 177000 Cl 127000 Mg 40000 Si 38600 Fe 2680 Zn 2110 Cu 76 I 14 Mn 13 F 13 Cr 7 Se 4 Mo 3 Co 1 Sterner R. W. & Elser J. J. Ecological Stoichiometry: The Biology of Elements from Molecules to the Biosphere. Princeton, NJ: Princeton University Press, 2002
08 Dec 2016 Dr. Retheesh Krishnan 3
Dr. Retheesh Krishnan 4
A long time ago….
Created in Big Bang H He 15 minutes to 100 m years Cecilia Payne- Gaposchkin
Created in Big Bang H He N O C As life progresses
Created in Big Bang H He Mg Na C The Final Centuries
Created in Big Bang H He P Si O C The Final Weeks
Fe The Final Day
The Last Second Li Be
B2FH The 1957 paper, suggested that heavy elements could be formed when Iron gets bombarded with neutrons and captures them in its structure U Pu In 2017, the idea was bolstered when the Laser Interferometer Gravitational Wave Observatory detected a neutron star collision with signature of Gold
B2FH La It takes more than 100 neutrons to convert Iron to Lanthanum. However White dwarfs hang around for plenty of time and produce these elements
Dr. Retheesh Krishnan 14 In 13.8 billion years
Dr. Retheesh Krishnan 15 The Periodic table
Dr. Retheesh Krishnan 16
Dr. Retheesh Krishnan 17 Symmetry
Dr. Retheesh Krishnan 18 Asymmetry Asymmetry: lack of equality or equivalence between parts or aspects of something; lack of symmetry.
Dr. Retheesh Krishnan 19 Right & Left Hands ~ 10%
Dr. Retheesh Krishnan 20 DNA
Dr. Retheesh Krishnan 21 Proteins
Dr. Retheesh Krishnan 22 James Bond 007
Dr. Retheesh Krishnan 23 Our Heart Actually part of cardiovascular systems consisting of blood vessels as well One among the five most important organs in our body In the fifth Intercostal Space ( Below the left Nipple ) at the Mid Clavicular line
Dr. Retheesh Krishnan 24 Our Heart Where is the apex beat of the heart felt? Torgerson,J : American Journal of Human Genetics, 2012 , 2, 361 - 370
28 Feb 2017 Dr. Retheesh Krishnan 26 Amino Acids L-amino acids predominate in living system Lamzin , V. S. et. al. : Current Opinion in Structural Biology, 1995 , 5 , 830 - 836 Petsko , G. A. Science, 1992 , 2 56 , 1403 - 1404 Milton, R. C. D. et. al. :Science , 1992 , 2 56 , 1445 - 1448
28 Feb 2017 Dr. Retheesh Krishnan 27 Sugars D-sugars predominate in living system Lamzin , V. S. et. al. : Current Opinion in Structural Biology, 1995 , 5 , 830 - 836 Petsko , G. A. Science, 1992 , 2 56 , 1403 - 1404 Milton, R. C. D. et. al. Science, 1992 , 2 56 , 1445 - 1448
28 Feb 2017 Dr. Retheesh Krishnan 28 But why clockwise ? Monocilia - arms are made of a protein called dynein Proteins are made of amino acids. They are asymmetric They are l-amino acids and hence the motor, has to be chiral. Hilfinger , A. et. al. Phys. Biol , 2008 , 5 , 1 - 12
Dr. Retheesh Krishnan 29 The Chicken Egg Problem
Dr. Retheesh Krishnan 30 No Longer a Conundrum Angew . Chem. Int. Ed. 2010 , 30 , 5135-5137
Dr. Retheesh Krishnan 31 Plastics Saga Jia et al. Sci. Adv. 2016 ; 2 : e1501591
Dr. Retheesh Krishnan 32 Plastics Saga Jia et al. Sci. Adv. 2016 ; 2 : e1501591
Dr. Retheesh Krishnan 33 Plastics Saga Jia et al. Sci. Adv. 2016 ; 2 : e1501591
Dr. Retheesh Krishnan 34 Plastics Saga Recyclable FDCA Ph o to tr i g g e r
Dr. Retheesh Krishnan 35 Plastics Saga https://phys.org/news/ 2014-11-ultimate-recycling-plastic .html
Dr. Retheesh Krishnan 36 The question is still open It is your turn / chance Now what ?
08 Dec 2016 Dr. Retheesh Krishnan 37 THANK YOU
Dr. Retheesh Krishnan 38 Questions
2/19/2021 Retheesh Krishnan 39 Career Prospects (after Graduation) Do we have a future ?
2/19/2021 Retheesh Krishnan 40 Chemistry Based Jobs - after B.Sc. Chemistry ?... Chemical Examiner’s laboratory Scientific Assistants Project Assistants Rubber Board, KCMMF Jobs in analytical labs Private sector (companies) jobs .. Not many…? Future Prospects
2/19/2021 Retheesh Krishnan 41 Future Prospects I would like to become a Teacher…! BSc – MSc – BEd . SET / UGC-CSIR-NET School College / University
2/19/2021 Retheesh Krishnan 42 B.Sc. Chemistry + B.Ed. in Physical sciences (now a two-year programme) High School Assistant Rs.30700-62000 M.Sc. Chemistry + B.Ed. in Physical sciences (now a two-year programme) Higher Secondary School Teacher Rs . 41500-83000 I would like to become a Teacher…!
2/19/2021 Retheesh Krishnan 43 Future Prospects
2/19/2021 Retheesh Krishnan 44 Future Prospects Universities University of Kerala Cochin University of Science and Technology M G University Calicut University Kannur University Central University of Kerala, Kasaragod Qualifying degree grade and/or entrance score
2/19/2021 Retheesh Krishnan 45 Future Prospects All candidates admitted through JAM should have a Bachelor’s degree. At least 55% aggregate marks, without rounding off , (taking into account all subjects, including Languages and Subsidiaries, all years combined) for General/OBC-NCL Category Candidates and at least 50% aggregate marks, without rounding off , for SC/ST and PwD Category Candidates in the qualifying degree. Admissions to M.Sc. (Four Semesters), Joint M.Sc.-Ph.D., M.Sc.-Ph.D. Dual Degree, M.Sc.- M.Tech ., etc. Programmes at the IITs Integrated Ph.D. Degree Programmes at IISc for consolidating Science as a career option for bright students. Application to be submitted by degree holder of final year student in the month September
2/19/2021 Retheesh Krishnan 46 Future Prospects
2/19/2021 Retheesh Krishnan 47 Future Prospects Integrated Ph.D. Programme @ IISER A Bachelor's degree in Chemical Sciences as applicable to individual Schools, under the 10+2+3/4 system. 55% marks or 6.0 out of 10 CGPA in the Bachelor's degree (as declared by the University). Relaxation of eligibility criteria for SC/ST and PD applicants will be made according to Government of India rules. Short-listed candidates will be called for a written test and those short-listed in the written test will appear for interview(s)
2/19/2021 Retheesh Krishnan 48 Future Prospects CSIR-UGC JRF/NET MCQ MSc or equivalent degree with at least 55% marks for general and OBC ( 50% for SC/ST candidates, physically and Visually Handicapped candidates). Final years M.Sc. students (Semester III & IV) also can apply Three hour exam session 200 Marks
2/19/2021 Retheesh Krishnan 49 Future Prospects PhD….Where to do ?? Kerala NIIST (CSIR-RRL), Trivandrum IISER, Trivandrum RGCB, Trivandrum SCIBMT, Trivandrum VSSC …. Central University of Kerala, Kasaragod Cochin University of Science and Technology University of Kerala M G University Calicut University Kannur University Universities Research Institutes
2/19/2021 Retheesh Krishnan 50 Future Prospects India Indian Institute of Science, Bangalore TIFR IISERs (7 Nos) All IITs (23 Nos.) – IIT Kanpur CSIR Laboratories (NCL, CLRI, RRLs… 39 Research Centres ) Reputed Universities Central Universities (49 Nos)
2/19/2021 Retheesh Krishnan 51 Top 10 Indian higher education institutions based on their global academic prestige. Future Prospects
2/19/2021 Retheesh Krishnan 52 Abroad North America (USA-GRE, Canada) Europe (UK, France, Italy, Germany, Belgium, Sweden, Denmark, Switzerland, Austria, Netherlands, Portugal) Asia (Japan-JSPS, South Korea, Taiwan, Singapore) Fellowships Future Prospects
2/19/2021 Retheesh Krishnan 53 Future Prospects Graduate Record Examinations (GRE) The entry pass to the graduate schools in United States http://www.ets.org/gre
2/19/2021 Retheesh Krishnan 54 Marie Skłodowska -Curie Actions (MSCA) PhD Funding Marie Skłodowska -Curie Actions (MSCA) offer funding for PhD students to study across Europe. The MSCA is now the main EU programme for doctoral training, financing 25,000 PhDs between now and 2020. https://euraxess.ec.europa.eu/ Masters Degree or equivalent qualification; Certificate of language proficiency (if required) Future Prospects
2/19/2021 Retheesh Krishnan 55 Future Prospects https://www.daad.de/deutschland/promotion/en/ DAAD research grants provide young foreign academics and scientists with an opportunity to carry out research and continue their education in Germany. There are funding programmes for various qualification phases and stages in a career. The grants also promote the exchange of experience and networking amongst colleagues.
2/19/2021 Retheesh Krishnan 57 Future Prospects Post doctoral fellowships https://www.humboldt-foundation.de/web/home.html https://www.jsps.go.jp/english/e-fellow/ http://ec.europa.eu/research/mariecurieactions/ Europe
2/19/2021 Retheesh Krishnan 58 Future Prospects Kerala NIIST (CSIR-RRL), Trivandrum IISER, Trivandrum RGCB, Trivandrum SCIBMT, Trivandrum VSSC …. Central University of Kerala, Kasaragod Cochin University of Science and Technology University of Kerala M G University Calicut University Kannur University Universities Research Institutes