Transdermal Patches Of Drug Delivery System

HOW TRANSDERMAL PATCHES ARE HELPFUL IN MEDICAL ASPECTS .TYPES OF PATCHES, USE OF PATCHES, DIFFERENT TYPE OF PATCHES.

1. REVIEW ON- TRANSDERMAL PATCHES OF DRUG DELIVERY SYSTEM Dr B.C. Roy College of Pharmacy & A.H.S NAME:ADITI ROY ROLL NO-18901914005 YEAR:3 RD PT-682 GUIDE BY-MR.SHOBHAN BOSE

2. Index- Introduction Types of transdermal drug delivery system Transdermal patch-definition Advantages of patch Disadvantages of patch Condition in which transdermal patches are used/not used Types of transdermal patches Modern examples

3. DEFINITION- Transdermal drug delivery is one of the system lying under the category of control drug delivery in which the drug is deliver to the skin at a predetermined & control rate.. Type of transdermal drug delivery system- Transdermal patch Transdermal film Transdermal gel

4. TRANSDERMAL PATCH- It is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin into the bloodstream. .

5. Advantages of patches- 1.Topical patches are a painless ,non invasive way to deliver substances directly into the body. 2.Topical patches are cost effective. 3.Topical patches over a controlled ,steady delivery of medication over long periods of time . 4.Dose delivery unaffected by vomiting & diarrhoea . 5.Avoid the first pass hepatic metabolism & 6.enzymetic degradation by the gastro intestinal track. 7.Less frequent dosing improve the patient compliance. 8.Drug administration stop with patch remove.

6. DISADVANTAGES OF PATCHES- Transdermal drug delivery system can not deliver ionic drugs. Drug molecule must be potent. Only small lypophilic drug can deliver to the skin. Adhesion may be vary with patch type & environmental condition

7. Condition in which transdermal patches are used- 1. W hen the patient has intolerable side effects and who is unable to take oral medication ( dysphagia )and is requesting an alternative method of drug delivery. 2 .Where the pain control might be improved by reliable administration.This might be useful in patient with congestive impairment or those who for other reasons are not able to self medicate with their analgesia .

8. Condition in which transdermal patches are not used- The use of transdermal patch is not suitable when- 1.cure for acute pain is required. 2.where rapid dose titration is required. 3.where requirement of dose is equal to or less than 30mg/24hrs.

9. Types of transdermal patches- Single- Layer Drug in Adhesive. Multi- Layer Drug in Adhesive. Reservoir Type. Matrix Type.

10. Single-layer drug in adhesive-

11. Multi-layer drug in adhesive-

12. Reservoir type-

13. Matrix type-

14. Picture- 4 types of patches are shown in this picture -

15. Modern examples- Nicotinic patch to get cessation of smoking. Fentanyl patch. Buprenorphine patch. Estrogen patch-treat menopausal syndrome. Nitroglycerin patch treatment of angina .

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