Zinc metalloenzymes

Includes carbonic anhydrates, carbonic peptidase and alcohol dehydrogenase

1. Zinc ENZYMES ZINC ENZYMES SUBMITTED BY- SIKANDAR GURJAR ENROLLEMENT NO- 2018MSCH020 1

2. 2

3. NATURE has selected Zn 2+ rather than Cu 2+ , why? 3

4. ZINC METALLOENZYMES 4

5. CARBONIC ANHYDRASE 5

6. CARBONIC ANHYDRASE 6

7. 7 Carbonic Anhydrates ( in resting state): Carbonic Anhydrates ( in action): With CO 2 With bicarbonate

8. 8

9. 9

10. 10 Mechanism

11. CARBOXYPEPTIDASE A carboxypeptidases is a proteas enzymes that hydrolyze a peptide bond at the carboxy terminal end of a peptide. This contrasts with aminopeptidases which cleaves peptide bond at the N-terminus of protein. The first carboxypeptidase studied were those involved in the digestion of food(Pancreatic carboxypeptidases A1,A2,and B). 11 STRUCTURE OF CARBOXYPEPTIDASE

12. MECHANISTIC ACTION 12

13. 13 Mechanism of Carboxypeptidase

14. 14

15. ALCOHOL DEHYDROGENASES 15

16. ALCOHOL DEHYDROGENASES 16

17. MECHANISM OF ALCOHOL DEHYDROGENASES 17