zygote interfelloporin transfer. Z*FT ppt

zygote interfelloporin transfer. Z*FT ppt

1. ZYGOTE
INTRAFALLOPIAN
TRANSFER
(ZIFT)

2. INTRODUCTION
•Zygote intrafallopian transfer (ZIFT): A technique in which a woman's egg is
fertilized outside the body, then implanted in one of her fallopian tubes.
•This technique is one of the methods used to overcome infertility, the inability of
couples to produce offspring on their own.

3. First, the egg and the male sperm needed to fertilize
it are harvested
Then the egg and the sperm are united in a petri
dish, a multi-purpose glass or plastic container with
a lid.
If all goes well, the sperm fertilizes the egg, and the
physicians then implant it in a fallopian tube.
From there, nature takes its course, and the egg
eventually is deposited by the fallopian tube into the
uterus (womb) for development

4. The term "intrafallopian" means "inside the fallopian
tubes." ("Intra," a Latin word, means "within" or "inside.").
Thus, the term "zygote intrafallopian transfer" refers to
the transfer of a zygote into a fallopian tube.

5. ZIFT is an assisted reproductive procedure similar to in vitro
fertilization and embryo transfer,
The difference being that the fertilized embryo is transferred into
the fallopian tube instead of the uterus.
Because the fertilized egg is transferred directly into the tubes, the
procedure is also referred to as tubal embryo transfer (TET).

6. This procedure can be
more successful than
gamete intrafallopian
transfer (GIFT)
because the physician has
a greater chance of
ensuring that the egg is
fertilized. The woman must
have healthy tubes for ZIFT
to work.
The main difference
between ZIFT and GIFT is
that ZIFT transfers a
fertilized egg directly into
the fallopian tubes while
GIFT utilizes a mixture of
sperm and eggs.

7. HOW IS ZIFT PERFORMED?
ZIFT is an assisted reproductive procedure that involves the following steps:
1
•A woman’s ovaries are stimulated with medications to increase the probability of producing multiple eggs.
2
•Eggs are then collected through an aspiration procedure.
3
•Those eggs are fertilized in a laboratory in a procedure identical to IVF, with the exception of the time frame.
During the ZIFT procedure, fertilized eggs are transferred within 24 hours, versus 3-5 days as used in a regular
IVF cycle.
4
•The fertilized eggs are then transferred through a laparoscopic procedure where a catheter is placed deep in the
fallopian tube and the fertilized eggs injected.
5
•The final step is to watch for early pregnancy symptoms. The fertility specialist will probably use a blood test to
determine if pregnancy has occurred.

9. ZIFT IS AN ASSISTED REPRODUCTIVE PROCEDURE WHICH MAY BE THE
SELECTED FORM OF TREATMENT FOR ANY INFERTILITY PROBLEMS EXCEPT
THE FOLLOWING:
Tubal blockage
Significant
tubal damage
An anatomic
problem with
the uterus,
such as severe
intrauterine
adhesions
Sperm that is
not able to
penetrate an
egg
ZIFT is commonly chosen by couples who have failed to conceive after at least one
year of trying and who have failed five to six cycles of ovarian stimulation with
intrauterine insemination (IUI).

10. WHAT ARE THE SIMILARITIES AND DIFFERENCES BETWEEN ZIFT AND IN
VITRO FERTILIZATION (IVF)?
ZIFT and IVF both tend to be favorable treatments for women who have more severe
infertility issues such as damaged fallopian tubes.
ZIFT and IVF both involve embryo culture.
ZIFT and IVF both provide the physician with the opportunity to select only the
best quality embryos for transfer.
ZIFT transfers the fertilized embryo into the fallopian tube whereas the IVF and
embryo transfer procedures result in the fertilized embryo being placed into the
uterus.
The ZIFT procedure differs from IVF in that the transfer of embryos into the tube
requires an extra surgical procedure called laparoscopy.

12. ADVANTAGES OF ZIFT
There are women who prefer ZIFT due to the fact that it
feels more ‘natural’.
This is because the embryo travels down the fallopian
tube towards the uterus without any external assistance.
Another benefit is that fertilisation takes place before
insertion into the fallopian tubes.
But with GIFT, this fertilisation takes place inside the
fallopian tube.

13. DISADVANTAGES OF ZIFT
•There is a danger of having an ectopic pregnancy, where the
hatchling will create outside the womb in the fallopian tube
itself.
•A few women may grow excessively numerous eggs because of
the fruitfulness of drugs.
•This can cause a few hormonal changes in the body, which are
hard to deal with.
•A few examinations additionally guarantee that infants
conceived through this treatment can have birth imperfections
or disorders.

14. WHAT IS THE SUCCESS RATE OF ZIFT?
The success rate for ZIFT varies
dramatically, depending on a
couple's fertility problem and
age
Younger women usually have
healthier eggs and higher
success rates.
Women have about a 22
percent chance of delivering
a baby with each ZIFT cycle –
similar to the IVF success
rate

15. ZIFT: WHAT YOU CAN EXPECT

This procedure is similar to GIFT in that the assisted
reproduction is done in the fallopian tubes.
The difference is that with ZIFT the sperm and egg are mixed
together in the laboratory, and given time to fertilize before being
placed in the fallopian tubes.
In this sense, ZIFT is closer to traditional in vitro fertilization.
ZIFT, like GIFT, requires treatment with hormones, and the
procedure is performed by laparoscopy.
Because ZIFT allows for fertilization to be confirmed before the
eggs are inserted into the fallopian tubes, fewer eggs are usually
used, lowering the risk of multiple pregnancy.

16. Risks from laparoscopy (which may be used to collect
eggs) include pelvic infection, puncture of internal
organs, and side effects from general anesthesia.
Assisted reproductive technologies—including
ZIFT—increase the risk of multiple births
A multiple pregnancy is high-risk for both the mother
and the babies.

17. HOW MUCH DOES ZIFT COST?

•In the United States, expect to
spend about $15,000 to $25,000
for one cycle of ZIFT. ZIFT is more
expensive than IVF or GIFT.
•The amount varies, depending on
how much medicine patient need,
where the couple live, and
whether the country mandates
insurance coverage for fertility
treatments.

18. WHAT TO THINK ABOUT???
ART birth rates can be misleading. As a woman ages past her
mid-30s, her egg quality and quantity decline.
This makes it increasingly unlikely that an ART procedure using
her own eggs will result in pregnancy and a healthy baby.
Many women over age 40 choose to use donor eggs. It greatly
improves their chances of giving birth to a healthy child.
ZIFT requires two separate procedures
The first is to collect the eggs from the woman's ovaries.
The second is done several days later when the fertilized egg
(zygote) is placed in her fallopian tube.