IX. Drug Study
Drug Name Classification Indications Mechanis
m of
Action
Adverse Effect Nursing
Considerations
Rationale
Generic
Name:
Diphenhydra
mine
Brand Name:
Oral: Allerdyl
(CAN),
AllerMax
Caplets,
Banophen,
Banophen
allergy,
Benaryl
allergy,
Diphen AF,
Diphenhist
Captabs,
Genahist,
Siladryl
Antihistamine,
Anti-motion-
sickness drug,
Antiparkinsoni
an,
Cough
Suppressant,
Sedative-
hypnotic
-> Relief of symptoms
associated with
perennial and seasonal
allergic rhinitis;
vasomotor rhinitis;
allergic conjunctivitis,
mild, uncomplicated
urticaria and
angioedema;
amelioration of allergic
reactions to blood or
plasma;
dermatographism;
adjunctive theraphy in
anaphylactic reactions.
-> Active and
prophylactic treatment
of motion sickness.
->Nighttime sleep aid
->Parkinsonism
(including drug induced
parkinsonism and
extrapyramidal
reactions), in the
elderly intolerant of
more potent drugs, for
milder forms of disorder
in the other age groups,
and in combination with
centrally acting
Competitiv
ely blocks
the effect of
histamine
at H1-
receptor
sites, has
antropine-
like,
antipruritic,
and
sedative
effects.
CNS: Drowsiness,
sedation, dizziness,
disturbed
coordination, fatigue,
confusion,
restlessness,
excitation,
nervousness, tremor,
headache, blurred
vision, diplopia
CV: Hypotension,
palpitations,
bradycardia,
tachycardia,
extrasystoles
stomatitis
G.I: Epigastric
distress, anorexia,
increased appétit and
weight gain, nausea,
vomiting, diarrhea r
constipation
G.U: Urinary
frequency, dysuria,
urinary retention, early
menses, decreased
libido, impotence
Hematologic:
Hemolytic anemia,
hypoplastic anemia,
-> Administer with
food.
->Avoid driving and
using Dangerous
machine.
-> Administer syrup
form for patient who
can’t take tablets.
->Advice patient to rise
slowly from lying or
sitting position.
->Monitor children
closely.
-> To
prevent GI
upset.
-> To avoid
accident
that may
cause by
the side
effects.
->To
prevent
aspiration.
->To
prevent
orthostatic
hypotensio
n
-> To
identify
paradoxica
l reaction.