American Type Culture Collection (ATCC).pptx

This ppt is based on Bioinformatics topic American Type Culture Collection (ATCC)

1. Course:- Bioinformatics Assignment:- American Type Culture Collection(ATCC) Submitted By:- Abhishek Suthar M.Sc. Biotechnology

2. Introduction:- The American Type Culture Collection (ATCC) stands as a cornerstone of scientific research, serving as a vital hub for the preservation, authentication, and distribution of biological materials essential to the advancement of various fields, including microbiology, biotechnology, medicine, and beyond. Since its inception in 1925, ATCC has played an instrumental role in facilitating scientific discovery and innovation by providing researchers, educators, and industry professionals with access to a vast array of well-characterized microbial strains, cell lines, and molecular materials. ATCC's comprehensive collections encompass a wide spectrum of biological specimens, ranging from bacteria, fungi, and viruses to human and animal cell lines. Each organism within the ATCC repository undergoes rigorous authentication, characterization, and quality control procedures to uphold the highest standards of accuracy and reliability.

3. Beyond its role as a repository for biological materials, ATCC actively fosters collaboration and knowledge exchange among researchers, industry partners, and other stakeholders. By facilitating partnerships and supporting scientific endeavors, ATCC contributes to the collective pursuit of understanding and addressing some of the most pressing challenges facing society today. As the landscape of scientific research continues to evolve, ATCC remains committed to innovation and excellence, constantly adapting and expanding its offerings to meet the evolving needs of the scientific community. Through its dedication to advancing scientific knowledge and promoting collaborative research efforts, ATCC continues to serve as a catalyst for progress and discovery in the biological sciences, shaping the future of research and innovation worldwide.

4. History:- 1925-Foundation: ATCC was formally established in 1925 in Washington, D.C., under the leadership of Dr. George W. McCoy, a prominent microbiologist. Recognizing the importance of standardized microbial cultures for research and education, McCoy and his colleagues laid the foundation for what would become one of the world's leading bioresource center Early Years: In its early years, ATCC focused on collecting, preserving, and distributing bacterial cultures to support research and educational institutions. The organization quickly gained recognition for its commitment to quality and reliability, becoming a trusted source of biological materials for scientists worldwide.

5. Expansion and Diversification: As scientific research advanced, ATCC expanded its collections to include a broader range of microorganisms, including fungi, viruses, and cell lines. This diversification reflected the growing demand for authenticated biological materials across various disciplines, from microbiology and immunology to biotechnology and medicine. Technological Advances: Throughout its history, ATCC has embraced technological innovations to enhance its operations and services. The organization has implemented state-of-the-art techniques for culturing, characterizing, and preserving biological specimens, ensuring the integrity and viability of Its collections.

6. Global Reach: ATCC's reputation for excellence and reliability led to its expansion beyond the United States, establishing collaborations and partnerships with institutions and organizations worldwide. This global reach facilitated the exchange of biological materials, expertise, and best practices, further advancing scientific research and collaboration on a global scale. Today and Beyond: In the 21st century, ATCC continues to uphold its legacy of excellence and service to the scientific community. With its vast collections, stringent quality control measures, and commitment to collaboration and innovation, ATCC remains a trusted partner for researchers, educators, and industry professionals worldwide. As science continues to progress, ATCC stands poised to address the challenges and opportunities of the future, driving discovery, innovation, and progress in the biological sciences.

7. Role and Significance:- The American Type Culture Collection (ATCC) plays a multifaceted and crucial role in the scientific community, serving as a global bioresource center that facilitates research, innovation, and collaboration across various disciplines. Below are key aspects highlighting the role and significance of ATCC:

8. Biological Resource Repository: ATCC serves as a repository for a vast collection of microbial strains, cell lines, and molecular materials. These biological resources are meticulously curated, authenticated, and maintained to the highest standards of quality and integrity. Researchers, educators, and industry professionals rely on ATCC's collections for conducting experiments, developing therapeutics, and studying disease mechanisms. Standardization and Quality Assurance: ATCC plays a pivotal role in standardizing biological materials, ensuring consistency and reproducibility in research outcomes. Through rigorous quality control measures and adherence to international standards, ATCC maintains the authenticity, purity, and viability of its biological specimens. This commitment to quality assurance is essential for advancing scientific knowledge and fostering trust within the scientific community.

9. Support for Research and Development: ATCC provides essential support for research and development activities in academia, industry, and government institutions. By offering access to authenticated biological materials, technical expertise, and educational resources, ATCC facilitates scientific inquiry, accelerates discovery, and drives innovation in fields such as microbiology, biotechnology, medicine, and agriculture. Facilitation of Collaboration and Partnerships: ATCC serves as a catalyst for collaboration and partnership within the scientific community. Through its global network of collaborators, ATCC fosters knowledge exchange, technology transfer, and interdisciplinary research initiatives. Collaborations with academic institutions, government agencies, pharmaceutical companies, and biotechnology firms enable ATCC to leverage expertise, resources, and infrastructure to address complex scientific challenges and societal needs.

10. Resource for Education and Training: ATCC plays a vital role in education and training by providing access to biological materials for academic and training purposes. Educators and students utilize ATCC's resources to conduct experiments, teach fundamental concepts in biology, and train future generations of scientists and healthcare professionals. By supporting education and training initiatives, ATCC contributes to building a skilled workforce and promoting scientific literacy. Global Impact and Outreach: ATCC's reach extends beyond national borders, making a global impact on scientific research and public health. Through collaborations, distribution agreements, and capacity-building initiatives, ATCC facilitates access to biological materials and expertise in regions around the world. This global outreach strengthens international scientific collaboration, promotes equity in access to research resources, and enhances global health security.

11. ATCC Collections:- The American Type Culture Collection (ATCC) maintains a diverse and extensive collection of biological materials essential for scientific research and development. Here's a breakdown of the various types of collections within ATCC: Microbial strains Cell lines Molecular materials Primary cells Microbiome collections Specialty Collections

12. Microbial Strains: ATCC houses a vast collection of microbial strains, including bacteria, archaea, fungi, and viruses. These microbial strains are essential for studying microbial diversity, characterizing microbial properties, and investigating microbial physiology, genetics, and pathogenesis. Cell Lines: ATCC offers a comprehensive collection of human, animal, and plant cell lines derived from various tissues and organs. These cell lines serve as valuable tools for studying cell biology, disease mechanisms, drug discovery, toxicology, and tissue engineering. ATCC's cell lines are authenticated, characterized, and maintained under optimal conditions to ensure their viability and functionality.

13. Molecular Materials: ATCC provides a wide range of molecular materials, including nucleic acids, proteins, and other biomolecules. These molecular materials are essential for molecular biology research, genetic engineering, genomics, proteomics, and other molecular techniques. ATCC offers purified nucleic acids, recombinant proteins, antibodies, and other molecular tools to support diverse research applications. Primary Cells: ATCC offers a collection of primary cells isolated from human, animal, and plant tissues. These primary cells retain their physiological characteristics and are valuable for studying tissue-specific functions, cell-cell interactions, and disease modeling. ATCC's primary cell collection includes a variety of cell types, such as epithelial cells, endothelial cells, neuronal cells, and stem cells.

14. Microbiome Collections: ATCC curates collections of microbiome samples from diverse environments, including the human microbiome, environmental microbiomes, and microbial communities associated with plants, animals, and insects. These microbiome collections are valuable for studying microbial ecology, microbiome-host interactions, and the impact of microbiota on health and disease. Specialty Collections: In addition to its primary collections, ATCC maintains specialty collections focused on specific research areas or applications. These specialty collections may include rare or unique biological materials, genetically engineered organisms, clinically relevant isolates, or materials tailored for specific research needs.

15. ATCC's Impact on Scientific Research:- The impact of the American Type Culture Collection (ATCC) on scientific research is profound and far-reaching, spanning multiple disciplines and areas of inquiry. ATCC's contributions to scientific research can be understood through several key aspects:

16. Access to High-Quality Biological Materials: ATCC provides researchers with access to a vast array of authenticated and well-characterized biological materials, including microbial strains, cell lines, and molecular materials. By offering these high-quality biological resources, ATCC enables researchers to conduct reproducible experiments, validate findings, and explore new avenues of inquiry. Advancement of Basic and Applied Research: ATCC's collections support a wide range of basic and applied research endeavors across diverse fields, including microbiology, immunology, oncology, infectious diseases, drug discovery, and biotechnology. Researchers utilize ATCC's resources to study microbial diversity, investigate disease mechanisms, develop new therapies, and explore novel biotechnological applications.

17. Support for Drug Discovery and Development: ATCC's cell lines and molecular materials are invaluable tools for drug discovery and development efforts in the pharmaceutical and biotechnology industries. Researchers use ATCC's cell-based assays and disease models to screen potential drug candidates, evaluate drug efficacy and safety, and elucidate mechanisms of action, accelerating the pace of drug discovery and improving patient outcomes. Contribution to Biomedical Research and Clinical Diagnostics: ATCC's collections have significant implications for biomedical research and clinical diagnostics. Researchers and clinicians utilize ATCC's biological materials to study disease pathogenesis, identify biomarkers, develop diagnostic tests, and monitor disease progression. ATCC's contributions to biomedical research have the potential to lead to new diagnostic tools, therapeutic interventions, and personalized medicine approaches.

18. Promotion of Collaborative Research Initiatives: ATCC fosters collaboration and knowledge exchange among researchers, educators, and industry partners through collaborative research initiatives, partnerships, and scientific conferences. By facilitating collaboration and interdisciplinary research, ATCC promotes the exchange of ideas, expertise, and resources, driving innovation and scientific progress.

19. ATCC Collaborations and Partnerships:- Collaborations and partnerships are integral components of the American Type Culture Collection's (ATCC) strategy to advance scientific research, promote innovation, and address complex challenges in the biological sciences. Here's a closer look at ATCC's collaborations and partnerships:

20. InSphero: ATCC and InSphero have formed a transformative strategic partnership to provide the scientific community with unprecedented access to assay ready 3-D tumor microtissues that will help accelerate oncology research at a global scale. US Pharmacopeia (USP): ATCC and USP have formed a strategic collaboration to offer exclusive new solutions to help biopharmaceuticals manufacturers and scientists advance the development of medicines, including biologics. Synthego: This strategic alliance brings together Synthego’s expertise in genome engineering and ATCC’s vast cell line collection to provide researchers with access to the cell model s and invaluable scientific resources needed to accelerate research.

21. QIAGEN: ATCC and QIAGEN have formed a alliance to provide the biotechnology and pharmaceutical industries with reference-quality transcriptomes tied back to well-characterized, authenticated human and animal cell lines from ATCC. National Institute of Standards and Technology (NIST): ATCC and NIST worked together along with scientists from 10 independent laboratories in the mouse cell line Authentication Consortium to validate the ATCC mouse STR profiling service. One Codex: ATCC and One Codex have formed a partnership to deliver best-in-class bioinformatics solutions for microbial genomics. This partnership has led to the launch of two key initiatives: The ATCC Genome Portal and ATCC NGS Standards.

22. How to use ATCC:-

23. Explore ATCC's Catalog : Begin by exploring ATCC's online catalog, which provides detailed information about the biological materials available for purchase or distribution. The catalog includes a wide range of microbial strains, cell lines, molecular materials, and other biological resources, organized by organism type, application, and research area. Select Biological Materials : Identify the specific biological materials needed for your research or project based on your experimental requirements, research objectives, and scientific interests. Consider factors such as organism type, strain specificity, cell line characteristics, and molecular properties when selecting biological materials from ATCC's catalog.

24. Place an Order : Once you've identified the desired biological materials, place an order through ATCC's online ordering system or contact ATCC's customer service team for assistance. Provide detailed information about the biological materials you wish to purchase, including catalog numbers, quantities, and any special requirements or instructions. Receive Biological Materials : After placing an order, ATCC will process and fulfill your request, packaging and shipping the biological materials to your designated shipping address. Depending on your location and shipping preferences, you may receive the biological materials within a few days to several weeks.

25. Handle Biological Materials Safely : Upon receipt of the biological materials, handle them with care and follow appropriate safety precautions to prevent contamination and ensure biosafety. Store the biological materials according to ATCC's recommended storage conditions and handling guidelines to maintain their viability and functionality. Authenticate Biological Materials : Before using the biological materials in your experiments or research studies, authenticate them to verify their identity, purity, and viability. Perform phenotypic, genotypic, or biochemical analyses as needed to ensure the accuracy and reliability of the biological materials obtained from ATCC.

26. Utilize Biological Materials in Research : Incorporate the biological materials obtained from ATCC into your research protocols, experiments, or projects as planned. Follow established protocols, experimental procedures, and best practices for working with microbial strains, cell lines, or molecular materials to achieve reliable and reproducible results. Share Research Findings : After conducting experiments or research studies using ATCC's biological materials, share your findings, data, and research outcomes with the scientific community through publications, presentations, or collaborations. Contribute to advancing scientific knowledge and promoting the responsible use of biological resources.

27. Provide Feedback to ATCC : Provide feedback to ATCC about your experience using their biological materials, including any suggestions, comments, or concerns you may have. Your feedback helps ATCC improve its products, services, and customer support to better meet the needs of the scientific community. By following these steps, researchers, educators, and industry professionals can effectively utilize the biological resources available from the American Type Culture Collection (ATCC) to support their scientific research, discovery, and innovation efforts.

28. References:- American Type Culture Collection Retrieved from https://www.atcc.org