ascorbic acid (libor zouhar). power poin

What is the importance of vitamin C, especially ascorbic acid

5. L – Ascorbic acidL – Ascorbic acid
Vitamin C
L – Ascorbic acid
SALEHA SAEEDSALEHA SAEED
MPHIL SCHOLARMPHIL SCHOLAR
UNIVERSITY OF PESHAWARUNIVERSITY OF PESHAWAR

6. Chemical formulas
Summary formula:
Geometrical formulas:
C
6
H
8
O
6
The effective form for treatment of colds and flu is the ascorbate form.
The bioactive form of vitamin C is only the L-form (synthetic
ascorbic acid: 50 % L-form + 50 % D-form; natural sources of
vitamin C contain only the L- form).

7. Chemical and physical properties
Molecular Weight:
Density:
176,13 g/mol
1,65 g/cm
3
pH:2,2-2,5 (50 g/l, 20 °C)
Solubility in water:330 g/l (24 °C)
Melting point:190-192 °C
LD
50 (oral, rat) :11900 mg/kg
Vitamin C is destroyed by oxygen, heat (above 70 °C),
light, freeze and reductans.

8. - Hungarian Nobel Laureate in Medicine (1937)
Albert von Szent-Györgyi Nagyrapolt (1893-1986)
He was the first who isolated vitamin C (in 1926).
Deficiency of vitamin C knew people
much more before as a scurvy. Scurvy
killed more sailors than were lost in all
sea battles.

10. Why is vitamin C „VITAMIN“ for man?
Man is one of the four mammalian species, who cannot produce
own vitamin C.
Mammalians need the four enzymes to make vitamin C.
We have the first three enzymes. The fourth enzyme we lost
somewhere in our evolution and so ascorbic acid became a vitamin
for us.
We have to obtain the vitamin C
from our diet.
Vitamin C should be consumed
every day because it cannot be
stored for later use.
RDA = 60 mg vitamin C

11. Sources of Ascorbic acid
Ascorbic acid is widely distributed in fresh fruits
and vegetables.
Rosehips
Amount of vitamin C
[mg / 100 g food]
Rosehip 2000
Kiwifruit 90
Broccoli 90
Orange juice (3/4 cup)75
Strawberry 50
Orange 50
Lemon 40
1 potato 25
Banana 9
Apple 6
Plant sources

12. "Vitamin C should be given to the patient
while the doctors found the diagnosis."
People who have
high blood levels of
vitamin C live 6
years longer than
those who have
lower blood levels.
Vitamin C is one of
the most important
vitamins.
Functions of vitamin C

13. The main function of Vitamin C in the body is
the manufacture of collagen, the main protein
substance of the human body. This protein makes
up the structures that hold our bodies together,
such as connective tissues, cartilage or tendons.
____________________________________________________________
Vitamin C is essential for wound repair and healthy gums.
Vitamin C plays an important role in all immune system
functions. It helps reduce cholesterol levels and high blood
pressure. Vitamin C is required for synthesis of dopamine,
noradrenaline and adrenaline in the nervous system.
Vitamin C is also needed to synthesise carnitine, important
in the transfer of energy to the cell mitochondria
……

14. Vitamin C is also a highly effective antioxidantantioxidant =
it can absorb free oxygen radicals. Even in small
amounts vitamin C can protect indispensable
molecules in the body, such as proteins, lipids,
carbohydrates, and nucleic acids (DNA and RNA)
from damage by free radicals.