Best pain killer tablet for body pain_pdf.pdf

Painkillers are the most commonly used medicines that help reduce pain sensation and inflammatory response. These medicines are also known as analgesics or anti-inflammatory drugs.

Analgesic medicines also improve the quality of life in long-lasting pain and help to relieve different pain conditions like generalized body pain, headaches, joint pain, muscle pain, etc.

They are broadly classified into three groups –

1. Paracetamol (Antipyretic)
2. NSAIDs (Non-Steroidal Anti-inflammatory Drugs)
3. Opioids (Narcotics)

Paracetamol has two important properties – antipyretic and analgesic. In other words, it can treat fever and mild to moderate body pain by inhibiting prostaglandin synthesis in the brain region.

However, it does not have anti-inflammatory properties. So, it would not work in swelling and severe pain.

As far as the concern of NSAIDs, these medicines have three important properties – antipyretic, analgesic, and anti-inflammatory.

NSAIDs generally decrease prostaglandin production by blocking cyclooxygenase enzymes (COX-1 and COX-2) or only COX-2.

If we talk about Opioids, it has only one property – analgesic. It does not work in inflammation. It blocks pain transmission by interfering with opioid receptors.

NSAIDs are usually preferred; if there is inflammation and pain.

In contrast, opioids are the strongest painkiller. These medicines are usually preferred if there is only visceral pain (or pain in internal organs like the heart, kidney, intestine, etc.), after surgery, burn, and cancer pain.

This post has discussed the best pain killer tablet names for various conditions.

Here, I have reviewed the best painkiller medicine for fever, acute pain, toothache, stomach pain, joint pain, muscle pain, and other body pain.

Moreover, I have explored the safest pain killer in children, pregnancy, asthma conditions, peptic ulcers, and heart disease conditions.

1. How to Choose Best Pain killer Tablet for Body
Pain in India
Posted BySUMIT SHARMA
●Introduction
●Anatomy & Physiology of Pain Pathway
●Learn about Painkiller
●List of best pain killer tablet names in India
●Best OTC pain reliever for body aches/fever
●Best pain killer for acute pain
●Best painkiller syrup for children
●Best pain killer tablet for toothache in India
➢Ibuprofen for toothache
➢Ketoprofen for tooth pain

2. ➢Opioids analgesic for tooth pain
●Best pain killer tablet for stomach pain or painful period
➢Hyoscine butylbromide tablets
➢Dicyclomine hydrochloride tablets
➢Drotaverine hydrochloride
➢Mefenamic acid
●Best pain killer tablet for headaches or migraine
●Best pain killer tablet for joint pain/muscle pain
➢Diclofenac sodium/potassium
➢Aceclofenac tablet
➢Piroxicam tablet
➢Indomethacin tablet
●Best pain reliever for osteoarthritis
●Best pain reliever for stomach ulcer patients
●Best pain relief for asthmatics
●Best painkiller for pregnant women
●Best strongest pain killer tablet in India
●Conclusion
●FAQ
➢Q 1. Which is the best pain killer tablet without side effects?
➢Q 2. Is Crocin/Dolo a painkiller?
➢Q 3. Is Combiflam a painkiller?

3. ➢Q 4. Which is the best pain killer tablet for knee and joint pain disorders?
➢Q 5 Which is strongest over the counter (OTC) painkiller?
Introduction
Wondering about the best pain killer tablet for body pain?
Well! It’s always hard to choose a good painkiller for body pain. The reason is that
no single medicine can treat every type of pain.
You must have felt pain in your daily routine, like a sports injury, muscle pain,
headache, tooth pain, back pain, neck pain and joint diseases.
Most people get confused about selecting the ideal painkiller.
But you don’t need to worry.
In this post, we will discover the best pain killer tablet for body pain.
Here, I have made a list of body pain killer tablet names that might be prescription
or OTC painkillers.
Apart from this, we will also see the best pain relief medicines for various pain
conditions such as toothache, headache, body pain, joint pain, muscle pain, acute
pain etc.
So, without further delay, let’s get started.
Anatomy & Physiology of Pain Pathway
Have you ever thought about why we feel pain?
Usually, our body is well decorated by pain detectors. These pain detectors are just
like the receptors, calledNociceptors.

4. Nociceptors are sensory receptors found at the nerve endings of the skin, joints,
muscles, etc.
These nociceptors are get activated when it gets stimulation like –
●Extreme high temperature
●Very low temperature
●Stretch
●Strain
●Pinch
●Injury
When you get a tissue injury, burns, body aches, insect bite or even a tiny pinch by
a needle.

5. These pain receptors are get activated and send a signal to yourbrain. After that,
your brain perceives it as pain and response.
Meanwhile, your body cells (mainly affected area) release a chemical called
arachidonic acid.
Arachidonic acid is released from your cell membrane and then binds to two
special enzymes called COX-1 or COX-2.
COX-1 or COX-2 is acyclooxygenaseenzyme.
COX-1 usually is present in our blood vessels, smooth muscle cells, platelets,
stomach, intestine and kidney.
Moreover, the COX-1 enzyme helps to maintain your body’s homeostasis and
manage your physiological function by –
●inhibit gastric acid secretion
●increase flow to the kidney
●help in blood clotting by platelet aggregation
Therefore, COX-1 is also known as the “housekeeping” enzyme.
While COX-2 is mainly responsible for pain,inflammation,and fever.
As soon as arachidonic acid binds to these two COX enzymes, arachidonic acid
converts intoprostaglandin.
Here, this prostaglandin is a major culprit in inducing fever, pain, and
inflammation by activating the COX-2 enzyme pathway.
Prostaglandin is also responsible for releasing other inflammatory chemicals like
thromboxane, nitric oxides etc.
You must have experienced redness, swelling, heat, and pain in the affected area.

6. These characteristics reflect the classical sign of inflammation. InLatin, it is also
known as –
●rubor(redness)
●tumour(swelling)
●calor(heat)
●dolor(pain)
●functio laesa(loss of function)
But somehow, prostaglandin is good for us.
Because the COX-1 enzyme helps in protective physiological functions by
releasing prostaglandin chemicals.

7. Learn about Painkiller
Do you know what a painkiller is?
Painkillers are the most commonly used medicines that help reduce pain sensation
and inflammatory response. These medicines are also known as analgesics or
anti-inflammatory drugs.
Analgesic medicines also improve the quality of life in long-lasting pain and help
to relieve different pain conditions like generalized body pain, headaches, joint
pain, muscle pain, etc.
They are broadly classified into three groups –
●Paracetamol(Antipyretic)

8. ●NSAIDs (Non-Steroidal Anti-inflammatory Drugs)
●Opioids (Narcotics)
Paracetamol has two important properties – antipyretic and analgesic. In other
words, it can treat fever and mild to moderate body pain by inhibiting
prostaglandin synthesis in the brain region.
However, it does not have anti-inflammatory properties. So, it would not work in
swelling and severe pain.
As far as concern of NSAIDs, these medicines have three important properties –
antipyretic, analgesic, and anti-inflammatory.
NSAIDs generally decreases prostaglandin production by blocking cyclooxygenase
enzymes (COX-1 and COX-2) or only COX-2.
If we talk about Opioids, it it has only one property – analgesic. It does not work in
inflammation. It blocks the pain transmission by interfering in opioids receptors.
List of best pain killer tablet names in India
Now it’s time to know the best pain killer tablet for body pain. There are various
classes of drugs used to control pain and inflammation.
Although it is classified into three major groups –
●Paracetamol (or acetaminophen) – Only for fever and pain
●Non-narcotic analgesic – NSAIDs for inflammatory pain
●Narcotic analgesic – Opioids for visceral pain

9. NSAIDs are usually preferred; if there is inflammation and pain.
In contrast, opioids are the strongest pain killer. These medicines are usually
preferred if there is only visceral pain (or pain in internal organs like the heart,
kidney, intestine, etc.), after surgery, burn and cancer pain.
Opioids do not have anti-inflammatory properties.
Here, I have made a list of prescription and non-prescription painkillers with
salient key features –
Category MedicinesKey points
Antipyretic and
analgesic
Paracetamol●Best medicine
for fever
●Safest pain killer
in pregnancy &
children

10. Non-Selective
NSAIDs
Aspirin ●At low dose
(50-360 mg) –
antiplatelet
activity
●At moderate
dose (300-600
mg) – analgesic
activity
●At high dose
(2-4 g) –
anti-inflammator
y activity
IndomethacinHighly potent
anti-inflammatory
property
Mefenamic
acid
Quite effective in
abdomen and
menstrual pain

11. IbuprofenSafest in children
KetorolacAvailable mostly in eye
drops & parenteral
preparations.
PiroxicamLongest acting pain
killer
NaproxenRecommended in acute
gout, ankylosing
spondylitis and
migraine.
Preferential COX-2
inhibitors(COX2>>
> COX1)
DiclofenacReach high
concentration in bones
and muscles
AceclofenacReach high
concentration in bones
and muscles
Nimesulide ●High risk of
hepatotoxicity
●More risk in
children

12. Selective COX-2
inhibitors
Etoricoxib ●Long-acting pain
killer
●Risk of heart
disease
●No gastric
disturbance
Opioids Morphine
injection
Drug of emergency
like pain during
myocardial infarction
Fentanyl ●100 times more
potent than
morphine
●Available for use
in cancer pain

13. Tramadol ●Use in mild to
moderate
short-lasting
pain
●Ineffective in
severe pain
Best OTC pain reliever for body aches/fever
We commonly suffer from nagging headaches, muscle spasms, general aches, and
joint problems. We don’t want to go to a doctor for minor pain.
SomeOTC(Over-the-counter) pain relievers are available,which don’t require a
prescription.
There is a variety of brands, which each have different active ingredients.
You must have heard the brand name of Dolo, Calpol, Paracip, etc. It contains
paracetamol.

14. Paracetamol should be the first medicine choice for mild pain or fever.
Paracetamol is also called acetaminophen. It works in your brain by inhibiting
prostaglandin production.
It has an excellent anti-pyretic effect because it works on COX-3 (present in the
brain). It is effective in migraine or headaches too.
If Paracetamol is ineffective during pain conditions such as toothache, headache,
body ache etc. In that case, you should always prefer NSAIDs.
In NSAIDs, you may take OTC NSAIDs like Aspirin (Disprin 325 mg), Naproxen
(Naprosyn) and Ibuprofen (Brufen, Ibugesic).
You must consult your doctor if you are not getting pain relief from OTC NSAIDs.
They may prescribe strong painkillers like prescription NSAIDs or Opioids.
Best pain killer for acute pain
Acute pain is generally sudden short-lasting pain. It only remains for a short time.
Suppose you get an injury like a cut, bruise, burn, broken bone, or pulled muscle.
In that case, you should choose a fast-relieving painkiller.

15. Although OTC painkillers (like Paracetamol, Ibuprofen and Naproxen) are always
the first choice for acute pain.
If an OTC painkiller does not work, your doctor may suggest a prescription
painkiller like Nimesulide.
Nimesulide is a quite effective medicine in short-lasting painful inflammatory
conditions such as sports injuries, fever, sinusitis, low backache, osteoarthritis, pain
after surgery, painfulfemale period, dental surgery,and ear-nose-throat disorders.
It gives instant relief within 15 minutes because it has the fastest onset of action.
One major problem with Nimesulide is that you may have a high risk ofliver
toxicity. That’s why it is banned in most countrieslike Spain, Turkey, Switzerland,
Spain, United states, etc.
But Nimesulide medicine is available in India with a black box warning.
It would be best to strictly avoidNimesulide in childrendue to hepatoxicity.
Popular brand names –Nicip, Nise, Nimutab
Best painkiller syrup for children
Choosing the safest pain reliever for children is challenging for everyone. Your
child may need a pain reliever to control pain sensations.
Here, you have limited options in choosing painkillers for kids. These are –
●Paracetamol Syrup (Paracip, Calpol suspension)
●Ibuprofen syrup (Ibugesic suspension)
●Combination of ibuprofen and paracetamol suspension (Ibugesic plus
suspension)

16. You may give these medicines to your child in mild to a moderate pain condition.
It would be better to ask your doctor before giving any painkillers to your child.
Also read,
●How tocalculate paracetamol dosefor children
●Albendazole dose for kids
Best pain killer tablet for toothache in India
Selecting an ideal tooth painkiller tablet can also be a real challenge.
According toAmerican Dental Association, 2022, NSAIDsand
NSAIDs/paracetamol combinations are considered the safest and first-line
treatment options for acute dental pain.
Ibuprofen for toothache
Among NSAIDs,Ibuprofenhas shown a satisfactory effectin managing toothache,
tooth extraction and dental surgery pain.

17. The analgesic efficacy of Ibuprofen is faster and better than other analgesic
medications without compromising safety.
Ibuprofen is an OTC (Over-the-counter) medicine. You can take this medicine
without a prescription for toothache or other body pain.
Ibuprofen starts to provide pain relief within 30 mins, giving you an analgesic
effect for 4 hours because its half-life is 2 hours.
You can take the next Ibuprofen 200/400 dose every 4 to 6 hours. But you should
not take more than 1200 mg per day.
Ibuprofen is also available in combination with Paracetamol. The combination of
ibuprofen and paracetamol tabletsis more effectivethan Ibuprofen alone.
It is trendy in the brand names Combiflam, Flexon, and Ibugesic plus tablets.
Ketoprofen for tooth pain
Ketoprofen is a prescription painkiller for tooth pain but is also available as an
OTC in some countries.
You may take theKetoprofenin the following toothacheconditions –

18. ●Severe tooth pain
●Inflammatory gums
●Tooth extraction pain
●Post-operative dental pain
If you are not getting pain relief from Ibuprofen. In that case, you may take25 to
75 mg of Ketoprofenthrice a day.
Opioids analgesic for tooth pain
If NSAIDs are ineffective in tooth pain, you may take opioids (like tramadol)
under proper medical supervision.
Opioids are potent analgesics, but they have a lot of side effects. Therefore, opioids
are reserved for a severe pain condition.

19. Best pain killer tablet for stomach pain or painful period
Some medicines are most widely used for treating stomach discomfort symptoms.
It includes –
Hyoscine butylbromide tablets
Hyoscine butylbromideis very popular in India witha brand name Buscopan
tablet.
It is an antispasmodic drug that belongs to a class of anticholinergic medications
(block M3 muscarinic receptors)
Hyoscine is also known as Scopolamine, and it is widely used to treat various
abdominal problems, such as –
●Abdominal cramp
●Stomach pain
●Period pain (dysmenorrhea)
●Stomach discomfort
●Motion sickness
You may get this drug as a prescription in many countries and without a
prescription (OTC).
Hyoscine also comes in a combination of Paracetamol and is available under the
brand name Buscopan Plus.
Dicyclomine hydrochloride tablets

20. Dicyclomine is also an anticholinergic drug that has antispasmodic action such as –
●Stomach pain
●Morning sickness
●Motion sickness
●Period pain
●Irritable bowel syndrome (IBS)
●Nausea and vomiting
Brand names– Colimex 20 mg, Diospas 10/20 mg, Cyclominol20 mg
Drotaverine hydrochloride
Drotaverineis another antispasmodic medicine thatbelongs to the anticholinergic
category (inhibiting Phosphodiesterase-4 enzyme)
The main benefit of this medicine is to treat painful abdominal problems without
showing anticholinergic side effects.
It is an effective medicine in the following conditions –
●Abdominal pain
●Irritable Bowel Syndrome (IBS)
●Intestinal colics (cramp-like pain in the small or large intestine)
●Renal colic (Kidney stone pain)

21. ●Biliary colics (Stones in the cystic duct or common bile duct)
●Menstrual pain
●Uterine spasms (Cramp in the uterus or pelvic area)
Brand names– Drotin 40/80 mg, Doverin 40/80 mg, Dotarin40/80 mg.
Mefenamic acid
Mefenamic acidis a quite effective medicine in painfulperiods (or dysmenorrhea).
The combination of tranexamic acid and mefenamic acid tablets relieves menstrual
pain and abnormally heavy menstrual bleeding.
Mefenamic acid is also used in post-operative pain (pain after operation or surgery)
and postpartum pain (pain in the bodyafter givingbirth or after delivery).
It belongs to the NSAIDs category of anthranilic acid derivatives.
Mefenamic acid has good analgesic and fever control properties but does not have
anti-inflammatory activity.
Therefore, you can use this drug if there is no inflammation, like soft tissue pain,
osteoarthritis and some muscle pain.
You may get this medicine in various brands like Medol 250/500 mg capsules and
Meftal 250/500 mg tablets.
It is also available in combination with other antispasmodic medicines, such as –
●Mefenamic acid and dicyclomine hydrochloride tablets (Cyclopam-MF,
Mefspas, Meftal spas)

22. ●Drotaverine hydrochloride and mefenamic acid tablets (Drotin M, DVN
plus)
Best pain killer tablet for headaches or migraine
You may take simple analgesics for headaches or mild migraines like Paracetamol
500 to 1000 mg thrice a day and Aspirin at high doses 300 to 600 mg (Disprin
Regular 325mg Effervescent Tablet) thrice a day.
If you are not getting relief from simple analgesics for migraine. Then you need to
take a combination of NSAIDs and antiemetic drugs under proper medical
supervision like –
●Domperidone and naproxen sodium tablets (Naxdom 250/500)
●Other NSAIDs (like Ibuprofen 400 to 800 mg, Diclofenac 50 mg,
Mefenamic acid 500 mg, Indomethacin 50 mg) with antiemetics (like
Metoclopramide 10 mg, Domperidone 10-20 mg, Prochlorperazine 10-25
mg)

23. Even if you are not getting relief, you must consult your doctor. Your doctor may
manage your medicine therapy as per the severity of your migraine pain.
They may prescribe some medicines for moderate and severe migraine –
●Vasograin tablet (Caffeine+ Ergotamine+ Paracetamol + Prochlorperazine)
●Ergot alkaloids
●Sumatriptan
●Propranolol
●Amitriptyline
●Flunarizine
●Valproate
Best pain killer tablet for joint pain/muscle pain

24. As you age, joint pain becomes more prevalent. Your doctor may recommend
prescription painkillers to help with joint or muscle pain. It includes –
Diclofenac sodium/potassium
Diclofenac has good tissue permeability, especially in the synovial fluid area.
It enters your bones and muscles with high concentration. That’s why Diclofenac is
widely used in acute joint pain conditions such as
●Bone pain (rheumatoid arthritis, gout, osteoarthritis,ankylosing spondylitis)
●Muscular pain, and
●Fracture pain.
So, Diclofenac is the best pain killer tablet for knee and joint pain disorders.
Moreover, Diclofenac causes lessgastric disturbancebecause it slightly interferes
with the COX-1 enzyme. So, it is also a good gastric-friendly painkiller.

25. You may also get a combination of diclofenac sodium and paracetamol tablets,
tolperisone hydrochloride and diclofenac sodium tablets, etc.
Popular brand names– Voveran, Diclonac, Movonac,Tolpidol D
Aceclofenac tablet

26. Now, aceclofenac is surpassing the benefits of Diclofenac.
According to published review literature inIndianJournal of Pain, 2016 –
aceclofenac is superior and more effective in various acute joint pain with fewer
side effects than Diclofenac.
Aceclofenac is a more gastric-friendly and longer-acting drug. So, aceclofenac is
also the best pain killer tablet for joint pain.
You can also get a combination of aceclofenac and paracetamol tablets.
Popular brand names– Zerodol, Dolokind, Aceclo
Piroxicam tablet
Piroxicam is a strong anti-inflammatory NSAID.
It is a prescription NSAID. Your doctor may prescribe Piroxicam 20 mg if you
exacerbate joint pain.
Piroxicam is quite effective in various joint disorders such as rheumatoid arthritis,
osteoarthritis, ankylosing spondylitis, acute gout, and musculoskeletal injuries.

27. It is the longest-acting drug that gives you a long-lasting anti-inflammatory effect
and short-term analgesic effect.
The longest acting (half-life 2 days) of piroxicam because of enterohepatic
recycling.
It can also be used in tooth pain and painful period.
Popular brand name– Dolonex DT 20 mg tablet and PiroxDT tablet
Side effects– Gastric disturbances like nausea, vomiting,gastric mucosal damage
and gastric ulcer
Indomethacin tablet
Indomethacin is also a prescription painkiller; you cannot take this medicine
without a prescription.
Indomethacin is also a potent anti-inflammatory drug. It is rarely used as a reserve
pain killer because of its severe side effects.
It can be used if other NSAIDs are ineffective.
The main use of indomethacin inankylosing spondylitis,arthritic pain and acute
gout.
It is a drug of choice inBarter Syndrome(excessprostaglandin production in the
kidney) and closure ofPDA(Patent Ductus arteriosus).
Popular brand names– Indocap SR capsule
Best pain reliever for osteoarthritis
Osteoarthritis is a non-inflammatory condition; you don’t need anti-inflammatory
painkillers (NSAIDs).

28. In this condition, Paracetamol is the most effective medicine for osteoarthritis.
It is recommended as thefirst choice of analgesicfor osteoarthritis. It is also
considered the safest analgesic than NSAIDs or opioids.
Your doctor may start paracetamol medicine in the early stage of osteoarthritis.
Best pain reliever for stomach ulcer patients
Generally, every NSAID causes gastric disturbance except COX-2 inhibitors.
Suppose you are suffering from body aches with pre-existing stomachulcer
problem.
In that case, you should choose COX-2 selective inhibitor NSAIDs. This class of
drugs does not cause a gastric disturbance.
Most of this class’s drugs (like Celecoxib, Rofecoxib, Valdecoxib) are banned due
to their cardiovascular risk.
Now, only one COX-2 inhibitor (i.e., Etoricoxib) is available in the market.

29. But you should strictly avoid selective COX-2 inhibitors if you are a patient of
ischemic heart disease,high blood pressure, and other heart diseases because it can
add additional risk.
Etoricoxib is a highly effective drug with better tolerability than non-selective cox
inhibitors.
It has a long half-life, around 24 hours. So, you don’t need to take the frequent
dose; once a day is sufficient for your treatment.
Etoricoxib tablet uses mostly in osteoarthritis, rheumatoid arthritis, gout,
ankylosing spondylitis, acute dental surgery pain, etc.
Best pain relief for asthmatics
Asthmatic people are more sensitive to aspirin or other non-selective NSAIDs.
These medicines are generally induced bronchospasm. So, they are contraindicated
in asthma conditions.
Certain medicines are recommended for asthmatics. These are –
●Paracetamol high dose
●Nimesulide

30. ●Etoricoxib
Best painkiller for pregnant women
Pregnancy is a delicate condition, and there is always a high risk for a premature
baby or mother. You don’t want to take any risk in this condition.
All NSAIDs and opioids are contraindicated in pregnancy. These drugs may cause
congenital disabilities and increase the risk of foetal life.
Paracetamol is the only choice for pregnancy. It isthe safest medicine to use for
fever/pain during pregnancy.
Aspirin can be a second option for pregnant women under proper medical
supervision.
Therefore, you should always consult your doctor before taking any painkiller
during pregnancy.
Also read,
●Safe drugs in pregnancy
●12 Shocking Risk Factors ofHigh Risk Pregnancy
●Development of the embryofrom fertilization to birth
Best strongest pain killer tablet in India
If your pain is more severe and unbearable. In this case, you will require opioids.
This is also prescription medicine but rarely used.

31. Opioids are narcotic analgesics that originate from the poppy plant. Generally,
opioids are classified into –
●Natural – Morphine, codeine
●Semi-synthetic – Heroin, Ethylmorphine
●Synthetic – Pethidine, Fentanyl, Methadone, Tramadol
They are a more powerful pain reliever than NSAIDs. It is generally safe when
prescribed for a short time.
Although, it has only one property – analgesic. It does not have the property to
treat fever and inflammation.
Opioid medicine only helps to reduce your pain sensation by blocking the
transmission of severe pain. It works on various opioid receptors – mu (μ), delta
(ẟ), and kappa (κ).
Among opioids, fentanyl is considered a highly potent medicine. It is 80-100 times
more potent (powerful) than morphine. While heroin is 3 times more potent than
morphine.
Thesemedicines are only used in emergenciesbecausethey have life-threatening
side effects.
These opioids are highly likely to develop an addiction because they produce
euphoria (which provides intense pleasure).
You should avoid opioids if you have respiratory problems likeemphysema,
pulmonary fibrosis, bronchialasthma, etc. Moreover,they may also cause
constipation problems.
Currently, tramadol is mainly prescribed and available under the brand name
Tramazac. It comes in tablet and injection form.

32. Tramadol works best with Paracetamol. It is available under the brand name
Ultracet semi, Tralam semi, Tromanil extra, Calpol T, etc.
It has fewer side effects than other opioids. It causes less constipation, respiration
problem, urinary retention, sedation, etc.
But you should not take this medicine if you are already takingantidepressant
drugs, especially SSRI (Selective Serotonin ReuptakeInhibitors), because of the
risk of ‘serotonin syndrome.’

33. Side effects of Opioids– Similar to the anticholinergic effects like respiratory
depression, decrease cough, sedation, constipation, urinary retention, anorexia,
meiosis (pinpoint), convulsion
Contraindication– Head injury, asthma, and biliarycolic
Conclusion
This post has discussed the best pain killer tablet names for various conditions.
Here, I have reviewed the best pain killer medicine for fever, acute pain, toothache,
stomach pain, joint pain, muscle pain, and other body pain.
Moreover, I have explored the safest pain killer in children, pregnancy, asthma
conditions, peptic ulcers and heart disease conditions.
This is only an informative article.
You don’t need to choose any painkiller yourself except OTC painkillers. It is
always better to consult your good doctor or pharmacist before taking any
painkiller medicine.
If you found this post (best pain killer tablet for body pain) informative, please
share it on social media.
FAQ
Q 1. Which is the best pain killer tablet without side effects?
Each medicine has pros (desirable effect) or cons (undesirable effect). Among all
painkillers, Paracetamol is considered the safest painkiller with minimum or
without side effects.

34. Q 2. Is Crocin/Dolo a painkiller?
Yes. Crocin and Dolo are painkillers. Both (Crocin and Dolo) contain paracetamol
medicine. It has two important properties – antipyretic and analgesic activity.
Therefore, you may take Crocin or Dolo for various pain conditions like headache,
migraine, dental pain, period pain, muscle pain etc.
Q 3.Is Combiflam a painkiller?
Yes. Combiflam is a good painkiller. It contains two medicines – Paracetamol and
Ibuprofen. They help to reduce pain, fever and inflammation.
Q 4. Which is the best pain killer tablet for knee and joint pain
disorders?
Diclofenac, Aceclofenac, and Etoricoxib medicines are the most frequently used
painkillers in joint disease.
Q 5 Which is strongest over the counter (OTC) painkiller?
Paracetamol and Ibuprofen are the only options for OTC painkiller medicine.
References
1. K.D. Tripathi. Essentials of Medical Pharmacology, 7thedition. Jaypee Brothers
Medical Publishers (P) Ltd; 2013. Chapter-14, Nonsteroidal Anti-inflammatory
Drugs and Antipyretic-Analgesics, Page-192.
2.Cardiovascular effects and safety of (non-aspirin)NSAIDs
3.NSAID induced gastrointestinal damage and designingGI-sparing NSAIDs

35. 4.Gastrointestinal safety of NSAIDs and over-the-counter analgesics
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