Blood banking

BLOOD BANKING

1. Blood banking Dr.T.Arivazhagan Department of Pathology

2. Introduction A place where blood is collected from donors, typed, separated into components, stored, and prepared for transfusion to recipients

3. Blood group system There are 30 blood groups systems are identified by ISBT Based on the red cell antigen ABO Rh Kell Lewis Duffy Kidd Colten……

4. Important ? ABO Rh Most immunogenic

5. No H antigen strong anti H ,anti A, anti B antibodies

6. Parameter ABO Rh type Location Chr 9 Chr 1 Antigens A,B,AB D Distribution RBC, Platelets, Body fluids RBC alone Antigen development Week express at birth Fully developed at birth Nature of antibodies Naturally occurring Immune Antibody class IgM IgG Compliment activation Yes No Optimal reaction medium Saline Antihuman globulin

7. Blood donation Types Voluntary Professional or paid Replacement

8. Donor selection process 4 parts Predonation counselling Medical history Physical examination HB estimation

9. Types of blood bags

10. Anticoagulant

11. Components & separation

12. Screening Malaria Syphilis HIV 1 & 2 Hepatitis B Hepatitis c