BURNING MOUTH SYNDROME BY DR. KIRAN KUMAR, NAVODAYA DENTAL COLLEGE, RAICHUR
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Added: Apr 27, 2022
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Dr Kiran Kumar K R Professor Dept of Oral Medicine & Radiology Navodaya Dental College
BURNING MOUTH SYNDROME Your information
Introduction Burning Mouth Syndrome (BMS) is a Chronic Orofacial Burning Pain condition. Usually in the absence of clinical and laboratory findings that affects many adults worldwide.
Is a variant of an atypical facial pain and Is usually described as a steady, continuous, though variable, typical superficial somatic pain.
Epidemiology Prevalent In Postmenopausal Women. In and about 10-40% of postmenopausal women presents with these symtoms . BMS was found in 3.9% of persons. However, Maresky et al. found the number of patients with BMS to be 35%
Etiology Etiologic factors are divided into two categories. 1. Local factors 2. Systemic factors
LOCAL FACTORS------ The possible local causes include Denture allergy, Galvanic current, Mechanical irritation, Parafunctional habits, Salivary dysfunction ( xerostomia ), Taste disturbances,
Ulcerative or erosive lesions, Gingivitis, Periodontitis , Candidiasis , Geographic tongue, and Peripheral nerve disease.
SYSTEMIC CONDITIONS-- --- Burning pain may be associated with systemic conditions such as Anemias , Nutritional disorders, Hematological disorders, Immunologic abnormalities, Diabetes mellitus, Psychiatric and psychological disorders,
Central nervous system disorders, Neoplasms , Polyglandular failure syndrome, Sjogren’s syndrome, Systemic lupus erythematosus , primary biliary cirrhosis and Autoimmune hemolytic anemia, and Menopause (Hormonal changes)
Clinical feature: Mainly affects middle-aged/old women with hormonal changes Middle-aged and elderly subjects with an age range from 38 to 78 years ( Basker et al., 1978 ). Acc. to Van der Waal, Occurrence below the age of 30 is rare . 7/10/2021
The female-to-male ratio is about 7:1 ( Bergdahl and Bergdahl, 1999 ). Tip of the tongue is the most common site 71% Lips 50%, lateral border of the tongue 46%, palate 46% 7/10/2021
Topical Systemic Cognitive behavioral therapy Initially, it is important to provide patients with information on the nature of their condition and give reassurance.
Topical Topical Lidocaine (anesthetic) -Viscous gel 2% -5 ml qid . -Rinse for two minutes and expectorate.
Oral rinse of Bzd HCL 0.15% , -used 3 times a day for 4 weeks -for each mouth wash, 15 mL, used for 1 min. Clonazepam 0.5-1mg, 3times/day Let tablet dissolve and hold fluid in mouth in area of most intense burning for three minutes, then spit.
Capsaicin - 0.025%, 3–4 times/day -Hot pepper and water -Rinse mouth with 1 teaspoon of a 1:2 dilution (or higher) of hot pepper and water; increase strength of capsaicin as tolerated to a maximum of 1:1 dilution. 7/10/2021
Systemic Medications Tricyclic antidepressants: Amitriptyline ( Elavil ) Nortriptyline ( Pamelor ) - 10 to 150 mg per day -10 mg at bedtime -Increase dosage by 10 mg every 4 to 7 days until oral burning is relieved or side effects occur 7/10/2021
Duloxetine -serotonin, norepinephrine reuptake inhibitor -60 mg qd -Start with 30 mg for one week then increase to 60 mg
Atypical anti-psychotic agent Trazodone 100 mg cap. of Trazodone in the evening for the first 4 days, & after this, the medication , increased to two 100 mg cap. Amisulpride -50 mg tablets up to three times per day. - Maximum dose not to exceed 400 mg/d 7/10/2021
Anticonvulsants Gabapentin ( Neurontin ) -300 to 1,600 mg per day -100 mg at bedtime; -increase dosage by 100 mg every 4 to 7 days until oral burning is relieved or side effects occur. -as dosage increases, medication is taken in three divided doses. Pregabalin 100 mg tid 7/10/2021
Benzodiazepines Clonazepam ( Klonopin ) -0.25 to 2 mg per day -0.25 mg at bedtime; - increase dosage by 0.25 mg every 4 to 7 days until oral burning is relieved or side effects occur. 7/10/2021
Others: Capsaicin: as 0.25% capsules t.i.d . for 4 weeks