Carbamazepine.pptx

Mood Stabilizer Mental Health Nursing Unit V

1. Presented by: Mr. P. Vethadhas M.Sc (N), Assistant Professor, Dept.of Mental Health Nursing. Unit - v MOOD STABILIZING DRUGS

2. CARBAMAZEPINE

3. CARBAMAZEPINE It is available in the market under different trade names like Tegretol , Mazetol , Zeptol and Zen Retard.

4. Indications

5. Seizures Complex partial seizures GTCS Seizures due to alcohol withdrawal .

6. Psychiatric disorders Rapid cycling bipolar disorder Acute depression Impulse control disorder Aggression Psychosis with epilepsy, Schizoaffective disorders Borderline personality disorder Cocaine withdrawal syndrome.

7. Paroxysmal pain syndromes Trigeminal neuralgia and Phantom limb pain.

8. Dosage The average daily dose is 600-1800mg orally, in divided doses. The therapeutic blood levels are 612µg/ml. Toxic blood levels are attained at more than 15µg/ml.

9. Mechanism of Action Its mood stabilizing mechanism is not clearly established. Its anticonvulsant action may however be by decreasing synaptic transmission in the CNS.

10. Side Effects Drowsiness Confusion Headache Ataxia Hypertension arrhythmias Skin rashes Steven-Johnson syndrome ,

11. Side Effects Nausea Vomiting Diarrhea Dry mouth Abdominal pain Jaundice Hepatitis

12. Side Effects Oliguria Leukopenia Thrombocytopenia Bone marrow depression leading to aplastic anemia.

13. Nurse's Responsibilities Since the drug may cause dizziness and drowsiness advise him to avoid driving and other activities requiring alertness. Advise patient not to consume alcohol when he is on the drug . Emphasize the importance of regular followup visits and periodic examination of blood count and monitoring of cardiac, renal, hepatic and bone marrow functions.

14. Thank you