chemdrawsoftware and incubator princpal and working.pptx

chemdraw and incubator

1. WELCOME CHEMDRAW & INCUBATOR PREPARED BY VIJISHA GEORGE REG.NO:200094223 ALEN THOMAS REG.NO:200094760

2. BY ALEN THOMAS Project report submitted to Kerala University of Health Sciences In partial fulfillment of the requirements for the award of the Degree of BACHELOR OF PHARMACY Under the guidance of Mrs. Anusha Anna Jacob, M.Pharm Associate Professor, Dept of Pharmaceutics Holy Queen College of Pharmaceutical Sciences and Research KERALA UNIVERSITY OF HEALTH SCIENCES THRISSUR – 680596 SEPTEMBER – 2024 INTRODUCTION TO CHEMDRAW AS A DRAWING & PREDICTION TOOL AND THEORY & WORKING OF AN INCUBATOR Reg. No: 200094760

3. DECLARATION We hereby declare that the project work, entitled “INTRODUCTION TO CHEMDRAW AS A DRAWING & PREDICTION TOOL AND THEORY & WORKING OF AN INCUBATOR ” which is being submitted to Kerala University of Health and Science, Thrissur, Kerala- 680596, was carried out by ALEN THOMAS (200094760) in the Department of Pharmaceutical Chemistry, Holy Queen College of Pharmaceutical Sciences and Research, Wadakkanchery, Thrissur, under the valuable and effective guidance of Anusha Anna Jacob M.Pharm , Associate Professor.,Department of Pharmaceutics, Holy Queen College of Pharmaceutical Sciences and Research, Wadakkanchery, Thrissur, during the academic year 2024- 2025. The work is original and has not been submitted for any Degree/Diploma of this or any other university. Mr. ALEN THOMAS Reg.No:200094760

4. Place: Wadakkanchery Date: Mobile : [phone] www.hqcopsar.com Phone : [phone] [email protected] HOLY QUEEN C0LLEGE OF PHARMACEUTICAL SCIENCES AND RESEARCH PUTHURUTHY PO, WADAKKANCHERY MUNICIPALITY, THRISSUR- 680623 ,KERALA CERTIFICATE This is to certify that the project work entitled “INTRODUCTION TO CHEMDRAW AS A DRAWING & PREDICTION TOOL AND THEORY & WORKING OF AN INCUBATOR ” submitted fulfilment for the award of Bachelor of Pharmacy to the Kerala University of Health Sciences, Thrissur, Kerala 680596 is a record of bonafide work carried out by ALEN THOMAS (200094760) And was guided and supervised by Anusha Anna Jacob M.Pharm ., Associate Professor., Department of Pharmaceutics, Holy Queen College of Pharmaceutical Sciences and Research, Wadakkanchery, Thrissur during the academic year 2024- 25 at our institution. Prof. Dr. MATHEW GEROGE, M.Pharm.,Ph.D.,Post Doc. USA, Europe Principal Holy Queen College of Pharmaceutical Sciences and Research Wadakkanchery, Thrissur,680623

5. INTRODUCTION ChemDraw is a software tool used in chemistry and related fields for drawing and predicting molecular structures. It allows users to create and modify molecular structures, predict properties, and perform calculations. ChemDraw can be used as a prediction tool to:- Predict molecular properties such as log P, polar surface area, and bioavailability Predict NMR spectra and other analytical data Perform molecular mechanics calculations and energy minimization as a drawing tool, ChemDraw enables users to:- Create and edit molecular structures and reactions Draw and modify chemical schemes and diagrams Generate names and formulas for molecules ChemDraw is a powerful tool for chemists, researchers, and students to visualize, predict, and communicate molecular information.

6. incubator An incubator is a device or equipment used to create a controlled environment for various applications, such as:- Biological incubators: used in laboratories to cultivate microorganisms, cells, or tissue cultures, maintaining optimal temperature, humidity, and gas levels Business incubators: programs supporting startups and early-stage companies, offering resources like funding, mentorship, and networking.- Egg incubators: used in poultry farming to hatch eggs under controlled conditions, ensuring optimal temperature, humidity, and rotation. Medical incubators: used in neonatal care to provide a stable environment for newborns, regulating temperature, humidity, and oxygen levels. In general, incubators aim to create a nurturing environment for growth, development, and success.

7. REVIEW OF LITERATURE 1. Greeves and Walter et al.,2011. Chemical Drawing Capabilities ; ChemDraw's primary function is to allow users to draw chemical structures with precision and ease. Key literature highlights include: User Interface and Usability: Studies have shown that ChemDraw's intuitive interface makes it accessible to both novices and experienced chemists. It offers drag-and-drop functionality, a comprehensive library of chemical symbols, and templates that streamline the drawing process 2. Williams & Smith et al.,2012. Predictive Capabilities ; ChemDraw has incorporated several predictive tools that enhance its functionality beyond mere drawing: Chemical Properties Prediction: ChemDraw can predict various chemical properties such as molecular weight, boiling points, and pKa values. This capability is crucial for chemists during the early stages of research when empirical data may not be readily available

8. 3. Brown and John et al., 2013. NMR and MS Spectral Prediction: The software can predict nuclear magnetic resonance (NMR) and mass spectrometry (MS) spectra, which are fundamental for structure elucidation. Studies have validated the accuracy of these predictions against experimental data 4. Harris and Lavoisier et al., 2014 Reactivity and Synthesis Prediction : Advanced versions of ChemDraw incorporate modules like ChemDraw Reaction Predictor, which suggest possible synthetic pathways and reaction mechanisms. This tool is especially useful for organic chemists designing synthetic routes

9. Aim and Objective This study aims; CHEMDRAW: Structural construction software. It is used as drawing and prediction tool. INCUBATOR: A laboratory incubator is a heated, insulated box used to grow and maintain microbiological or cell cultures. OBJECTIVES CHEMDRAW; Draw and predict both chemical and biological structure. INCUBATOR; Provide optimal growth conditions for cells or cultures. It is also used to maintain the viability of cell lines and bacteria strains

10. Materials required 1. CHEMDRAW SOFTWARE ChemDraw is a software tool used for drawing and publishing chemical structures and reactions. It's a popular program in the chemistry field, especially among researchers, scientists, and students Create and edit chemical structures and reactions accurately and efficiently. Provide a powerful tool for chemists, researchers, and students to communicate chemical information clearly and effectively. Assist in the design, synthesis, and analysis of molecules and reactions. Predict chemical properties and behavior, such as physical properties, spectroscopy, and reactivity. Facilitate the search, sort, and organization of chemical data and libraries. Enable the creation of professional-quality documents, presentations, and publications. Support research and development in various fields, including drug discovery, materials science, and biotechnology. Aid in the teaching and learning of chemistry, from basic concepts to advanced research topics.

11. 2. INCUBATOR An incubator is a device or apparatus used to maintain a controlled environment, often at a constant temperature, humidity, and oxygen level, to support the growth and development of living organisms, such as: Bacteria or cells in a laboratory setting Eggs in a poultry hatchery Premature infants in a neonatal intensive care unit (NICU) Plant seedlings in a greenhouse or nursery Provide a controlled and optimal environment for growth and development. Support the survival and success of fragile or vulnerable living organisms. Foster healthy development and growth. Enhance viability and chances of success. Monitor and control environmental factors to prevent adveres

12. METHODOLOGY

13. METHODOLOGY ChemDraw working demonstration Fig.no:1 Fig.no:2 13

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19. Incubator An incubator is based on the principle that microorganisms require a particular set of parameters for their growth and development. All incubators are based on the concept that when organisms are provided with the optimal condition of temperature, humidity, oxygen, and carbon dioxide levels, they grow and divide to form more organisms. In an incubator, the thermostat maintains a constant temperature that can be read from the outside via the thermometer. The temperature is maintained by utilizing the heating and no-heating cycles. During the heating cycle, the thermostat heats the incubator, and during the no-heating period, the heating is stopped, and the incubator is cooled by radiating heat to the surrounding. Insulation from the outside creates an isolated condition inside the cabinet, which allows the microbes to grow effectively. Similarly, other parameters like humidity and airflow are also maintained through different mechanisms that create an environment similar to the natural environment of the organisms. Similarly, they 24 are provided with adjustments for maintaining the concentration of CO2 to balance the pH and humidity required for the growth of the organisms. Variation of the incubator like a shaking incubator is also available, which allows for the continuous movement of the culture required for cell aeration and solubility studies. Procedure for running an incubator Once the cultures of organisms are created, the culture plates are to be placed inside an incubator at the desired temperature and required period of time. In most clinical laboratories, the usual temperature to be maintained is 35–37°C for bacteria.

20. CHEMDRAW : Results and discussion in ChemDraw typically refer to the output and interpretation of molecular modeling and prediction experiments. Here are some possible results and discussion points: Results:- Molecular structures and optimized geometries- Predicted molecular properties (e.g., log P, polar surface area, bioavailability) NMR spectra and other analytical data predictions- Molecular mechanics calculations and energy minimization results Discussion:- Interpretation of molecular structure and property predictions Comparison with experimental data or literature values Analysis of structure-property relationships- Implications for drug design, synthesis, or biological activity- Optimization of molecular structures for specific applications In ChemDraw, results and discussion may also involve visualizing and analyzing molecular structures, reactions, and datasets to extract insights and meaningful patterns. INCUBATOR ;Biological Incubator: Results:- Cell growth and viability- Microbial cultures or tissue cultures- Gene expression or protein production Discussion:- Analysis of cell growth and viability- Evaluation of microbial or tissue culture success- Interpretation of gene expression or protein production data Egg Incubator: Results:- Hatching success rate- Chick health and viability- Incubation period and temperature control Discussion:- Analysis of hatching success factors- Evaluation of incubation conditions and chick health- Optimization of incubation parameters Medical Incubator (Neonatal): Results:- Newborn health and viability- Weight gain and development- Incubation period and temperature control Discussion:- Analysis of newborn health and development- Evaluation of incubation conditions and care- Strategies for optimizing neonatal health outcomes RESULTS AND DISCUSSION

21. SUMMARY AND CONCLUSION ChemDraw: Summary:- ChemDraw is a software tool for drawing and predicting molecular structures and properties.- It allows users to create and modify molecules, predict properties, and perform calculations. Conclusion:- ChemDraw is a powerful tool for chemists, researchers, and students to visualize, predict, and communicate molecular information.- Its applications in drug design, synthesis, and analysis make it an essential tool in the field of chemistry. Incubator: Summary:- An incubator is a device or program that creates a controlled environment for growth, development, and success.- Types of incubators include biological, business, egg, and medical (neonatal) incubators. Conclusion:- Incubators play a crucial role in various fields, including biology, business, agriculture, and medicine.- By providing optimal conditions, incubators support growth, development, and success, leading to breakthroughs, innovation, and improved outcomes.

22. THANK YOU