Commonly used instruments in experimental pharmacology

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1. Commonly Used Instruments in
Experimental Pharmacology
Pharma Learning Forever
Prof. Shaikh Abusufiyan
Assistant Professor,
AIKTC-School of Pharmacy,
New Panvel-410206

2. At the end of this e-learning session you are able to…
qIdentify commonly used instruments
and their applicationin experimental
pharmacology.
2

3. Basic Instrument For recording contraction of muscles

4. qKEYMOGRAPHMACHINE:
ØRequirements:
•RotatingDrum
•Organbathwiththermostat
•AerationTube
•Recordinglever
•PSSReservoir

5. Digitalkymographmachinewith
rotatingdrum:

6. Organbathwiththermostat

7. AerationTube/OxygenTube

8. Recordinglever

9. PSSReservoir

10. Q&A
Q.1Giverequirementforbasicsetupneededforrecording
contractionofmusclesbyusingkeymographmachine?
Q.2 What is use of organ bath?
Q.3Whatisroleofrecordinglever?
1
0

11. Instruments for evaluation of Invivo
Experiments

12. HotPlateAnalgesiometer:
•Application:Forstudyinganalgesic
activityofdrugs.
•ExampleofdrugEvaluated:Morphine,
Aspirinetc

13. Electro-convulsiometer:
•Application:Forstudyinganti-
convulsantactivitybyusingMES
inducedconvulsion.
•ExampleofDrugEvaluated:Phenytoin.

14. ACTOPHOTOMETER
•Application:ForstudyingbothCNS
StimulantandCNSdepressantdrugs
•ExampleofDrugEvaluated:
•CNSStimulant:Caffeine
•CNSDepressant:Diazepam

15. ROTARODAPPERATUS
•Application:Forstudyingmuscle
relaxantactivityofdrugs
•ExampleofDrugEvaluated:
•Diazepam

16. COOK’SPOLECLIMBING
APPARATUS
•Application:Forstudyingcognitive
functionspeciallyincaseofanti-
psychoticdrugs
•ExampleofDrugEvaluated:
•Chlorpromazine

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