Cryosurgery_Journal_Club FOR MUCOCELE PRESENTATION

JOURNAL CLUB

1. Analysis of effects and indications of cryosurgery for oral mucoceles Dr.avanthika sasankan

2. Introduction Cryosurgery: destruction of tissue at low temperatures (≤ -20°C) Used in oral and maxillofacial surgery for tumors, cysts, precancerous lesions Benefits: simple, safe, painless, minimal complications

3. aim evaluate clinical efficacy and indications of cryosurgery for oral mucoceles

4. Design of the Study Retrospective clinical study Conducted at Iwate Medical University (2019–2020) Ethics approval obtained

5. Inclusion criteria patients with mucoceles of lip/buccal mucosa (minor salivary glands )

6. Exclusion criteria severe systemic illness

7. Procedure Device: Cryo-AC with liquid nitrogen (–20°C to –190°C) Frozen probe (8 mm) applied to lesion for 30 sec Thawed for 30 sec, repeated 2–3 times Total treatment < 5 min Performed without anesthesia

8. Clinical Examination Parameters: age, sex, lesion size, duration, number of treatments, healing time Recorded symptoms: pain, swelling, stomatitis Follow-up until healing and recurrence confirmation Surgical excision if cryosurgery failed or requested

9. Statistical Analysis Data grouped by: - Lesion duration (≤ 3 months vs > 3 months) - Age (≤10, 11–20, ≥21 years) - Lesion size (≤5 mm vs >5 mm) Analysis: ANOVA, t-test Software: Excel v10

10. Results – Cases 47 patients total (18 men, 29 women) 24 chose cryosurgery (age range: 2–83 yrs) 23 chose surgical excision (age range: 8–82 yrs) Younger patients significantly preferred cryosurgery

11. Clinical Findings Cryosurgery group: - 22/24 cases cured - 14 cases cured with single treatment - Healing period: 2–20 weeks (avg 6.2 weeks) - Side effects: swelling, stomatitis, pain, induration Surgical excision group: - 1 recurrence - 1 paresthesia - 1 hematoma

12. Analysis of Clinical Data No significant difference in healing period based on: - Lesion duration - Age group - Lesion size Average age: Cryosurgery 21 yrs vs Excision 40 yrs (p < 0.01)

13. Histological Findings Mucus pools surrounded by fibrous tissue, inflammatory cells Minor salivary glands showed atrophy but some functional acini persisted Suggests inadequate freezing may lead to recurrence

14. Discussion Cryosurgery effective for mucoceles with minimal discomfort Advantageous in children: no anesthesia, outpatient procedure Healing longer than excision due to tissue degeneration Main limitation: no histopathology confirmation Adverse events mild and self-limiting

15. Conclusion Cryosurgery is a simple, safe, and effective treatment for mucoceles Especially useful in preschool children (no anesthesia required) Should be considered a primary treatment option depending on patient’s age and preference

16. Merits of the Study Demonstrates safety and efficacy of cryosurgery Highlights special benefits in preschool children and elderly Provides clinical and histological correlation

17. Demerits of the Study Retrospective design, small sample size No long-term recurrence data No histopathology for cryosurgery cases Limited to lip and buccal mucosa lesions

18. THANKYOU