Development of spinal cord

Development of spinal cord

1. E M B R Y O L O G Y By; RazaRehman, 152 Maria Ilyas, 148 Isfandyar; 156 Spinal Cord

2. N e u r al T u b e Ar i s e s fr o m t h e e c t o d e r m o v e r l y i n g t h e n oto c h o r d G i v e s r i s e t o t h e b r a i n a n d s p i n a l c o rd

3. N e u r al T u b e F or m a t i o n T h e n e u r a l pl a t e f o l d s t o f o r m n e u r a l g roo v e w i t h p r o m i n e n t n e u r a l f o l d s T h e n e u r a l fo l d s a pp r o a ch e a c h ot h e r w i t h d e e p e n i n g o f t h e n e u r a l g roo v e

4. N e u r al T u b e F or m a t i o n T h e n e u r a l fo l d s f u s e a n d a n e u r a l t u b e i s for m e d T h e t u b e , t h e n , s e p a r a t e s fr o m t h e o v e r l y i n g e c t o d e r m

5. Development of Spinal Cord Nuero epithilial cells form: Ventricular zone Ependymal cells Intermediate zone Form from neuroblasts Marginal zone - Forms white matter

6. D ev e l o p m e n t o f t h e S p i n a l C o r d T h e c e ll s o f t h e n e u r a l t u b e m ig r a t e t o f o r m t h e m a n t l e l a y e r of g r a y m a tt e r w h i c h d i ff e r e n t i a t e s i n t o Q A n a l a r pl a t e , mo s t l y s e n s o r y n e u r o ns Q A b a s a l pl a t e , mo s t l y mot o r n e u r o n s . Q S e p a r a t e d b y s u l c uc l i m i t a ns

7. D ev e l o p m e n t o f t h e S p i n a l C o r d T h e c e ll s of t h e m a n t l e l a y e r h a v e a x o n s w h i c h c o ll e c t i n t h e m a r g i n a l l a y e r of w hi t e m a tt e r

8. Meninges Dura mater External layer Pia arachnoid - Separated by arachnoid trabeculae Develop from neural crest cells

9. N e u r al C re s t C e ll s O r i gi n a te f r o m c e l l s o f n e u r a l f o l d s . L i e b e tw e e n t h e n e u r a l t ub e a n d s u r f a c e e c t o d e rm .

10. N e u r al C re s t C e ll s T h e y , t h e n , m ig r a t e t o n e w l o c a t i on s ; gives m a n y d e r i v a t i v e s G A M E S G a n g l i o n c e ll s (D R G , C r a n i a l s e n s o r y , A u t o n o m i c) A r a c h n o id a n d p i a m a t e rs M e l a n o c y t e s , M es e nc h y m e o f th e ph a r y n g e a l a rc h e s E n t e r ic g a n g l i a S c h w a n n c e ll s , S u p r a r e n a l m e d u ll a c e ll s