DPT - Biochemistry & Genetics - II (Molecular Biology) Prokaryotic Transcription

DPT - Biochemistry & Genetics - II (4th Semester)

1. Prokaryotic transcription Areesha Ahmad Microbiology Lecturer Ph.D scholar Microbiology

2. Sigma factors are multi-domain subunits of bacterial RNA polymerase (RNAP) that play critical roles in transcription initiation, including the recognition and opening of promoters as well as the initial steps in RNA synthesis. C ore enzyme  consists of four subunits (α 2 ββ ') contains the polymerase catalytic function. The interaction between this core enzyme and a σ factor results in an RNA polymerase holoenzyme that can detect specific promoter sequences and activate transcription

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