Electronic tongues

Electronic tongues - Introduction, Principle , Correlation with human tongue, Instrumentation, Advantages, Limitations, Applications and Conclusion.

1. ELECTRONIC TONGUES Presented by : Monika Jalindar Pandarkar M.Pharm Sem II (Pharmaceutics) Roll no.- 511 Guide : Dr N. S. Ranpise M. Pharm, PhD Sinhgad College of Pharmacy, Vadgaon (Bk), Pune-41

2. INTRODUCTION Electronic tongue – An analytical instrument that measures and compares tastes. Non-specific, low selective chemical sensors with cross-sensitivity to different components in solution. An appropriate method of pattern recognition or multivariate calibration for the data processing. Major interest-Assessment of the taste of oral drugs especially for pediatrics. 2 511. Monika J.Pandarkar 16 June 2022 Woertz, K., Tissen, C., Kleinebudde, P. and Breitkreutz, J., 2011. Taste sensing systems (electronic tongues) for pharmaceutical applications.  International journal of pharmaceutics ,  417 (1-2), pp.256-271

3. PRINCIPLE Substance with specific taste Interaction Sensors with specific properties Change of sensor properties Amplification/Recording Univariate data analysis Multivariate data analysis 3 511. Monika J.Pandarkar 16 June 2022 Woertz, K., Tissen, C., Kleinebudde, P. and Breitkreutz, J., 2011. Taste sensing systems (electronic tongues) for pharmaceutical applications.  International journal of pharmaceutics ,  417 (1-2), pp.256-271

4. CORRELATION WITH HUMAN TONGUE 4 511. Monika J.Pandarkar 16 June 2022 Latha, R.S. and Lakshmi, P.K., 2012. Electronic tongue: an analytical gustatory tool.  Journal of advanced pharmaceutical technology & research ,  3 (1), p.3.

5. Biological system Tongue Brain Sensor array Data processing system Pattern recognition Samples Acquisition Data processing Decision results Electronic tongue Conti … Food taster 5 511. Monika J.Pandarkar 16 June 2022 Latha, R.S. and Lakshmi, P.K., 2012. Electronic tongue: an analytical gustatory tool.  Journal of advanced pharmaceutical technology & research ,  3 (1), p.3.

6. INSTRUMENTATION 6 511. Monika J.Pandarkar 16 June 2022 Gupta, H., Sharma, A., Kumar, S. and Roy, S.K., 2010. E-tongue: a tool for taste evaluation.  Recent patents on drug delivery & formulation ,  4 (1), pp.82-89. Liquid Autosampler Chemical Sensor or Sensor array Acquisition System Data Processing System

7. ADVANTAGES 7 511. Monika J.Pandarkar 16 June 2022 Jain, H., Panchal, R., Pradhan, P., Patel, H. and Pasha, T.Y., 2010. Electronic tongue: A new taste sensor.  International Journal of Pharmaceutical Sciences Review and Research ,  5 (2), pp.91-96.

8. LIMITATIONS 8 511. Monika J.Pandarkar 16 June 2022 Jain, H., Panchal, R., Pradhan, P., Patel, H. and Pasha, T.Y., 2010. Electronic tongue: A new taste sensor.  International Journal of Pharmaceutical Sciences Review and Research ,  5 (2), pp.91-96.

9. APPLICATIONS 9 511. Monika J.Pandarkar 16 June 2022 Woertz, K., Tissen, C., Kleinebudde, P. and Breitkreutz, J., 2011. Taste sensing systems (electronic tongues) for pharmaceutical applications.  International journal of pharmaceutics ,  417 (1-2), pp.256-271

10. ELECTRONIC TONGUES USED FOR PHARMACEUTICAL APPLICATIONS 10 Woertz, K., Tissen, C., Kleinebudde, P. and Breitkreutz, J., 2011. Taste sensing systems (electronic tongues) for pharmaceutical applications.  International journal of pharmaceutics ,  417 (1-2), pp.256-271.

11. Conti… 11 Woertz, K., Tissen, C., Kleinebudde, P. and Breitkreutz, J., 2011. Taste sensing systems (electronic tongues) for pharmaceutical applications.  International journal of pharmaceutics ,  417 (1-2), pp.256-271. Taste sensing system TS-5000Z α Astree2

12. CONCLUSION Electronic tongues are emerging, promising and proved to be a valuable tool for assessing and predicting the taste of a wide range of products. It replaces human panels in routine analysis in pharmaceutical development and production . The exposure and risk of using human panel to test products is greatly reduced, permitting better analytical results to quickly define the best formulation and get the product to market. 12 511. Monika J.Pandarkar 16 June 2022

13. REFERENCE Woertz, K., Tissen, C., Kleinebudde, P. and Breitkreutz, J., 2011. Taste sensing systems (electronic tongues) for pharmaceutical applications.  International journal of pharmaceutics ,  417 (1-2), pp.256-271. Tahara, Y. and Toko, K., 2013. Electronic tongues–a review.  IEEE Sensors Journal ,  13 (8), pp.3001-3011. Jain, H., Panchal, R., Pradhan, P., Patel, H. and Pasha, T.Y., 2010. Electronic tongue: A new taste sensor.  International Journal of Pharmaceutical Sciences Review and Research ,  5 (2), pp.91-96. Latha, R.S. and Lakshmi, P.K., 2012. Electronic tongue: an analytical gustatory tool.  Journal of advanced pharmaceutical technology & research ,  3 (1), p.3. Podrażka, M., Bączyńska, E., Kundys, M., Jeleń, P.S. and Witkowska Nery, E., 2017. Electronic tongue—a tool for all tastes?.  Biosensors ,  8 (1), p.3. 13 511. Monika J.Pandarkar 16 June 2022

14. REFERENCE Gupta, H., Sharma, A., Kumar, S. and Roy, S.K., 2010. E-tongue: a tool for taste evaluation.  Recent patents on drug delivery & formulation ,  4 (1), pp.82-89. MOHAMED, E.I. and ABDEL-MAGEED, S.M., 2010. The Electronic Tongue–Basic Principles and Medical Applications.  Journal of Biophysics and Biomedical Sciences September ,  3 (2), pp.290-295. Ciosek, P., Wróblewski, W., 2007. Sensor arrays for liquid sensing – electronic tongue systems. Analyst 132, 963–978. Vlasov, Y., Legin, A. and Rudnitskaya, A., 2002. Electronic tongues and their analytical application.  Analytical and Bioanalytical Chemistry ,  373 (3), pp.136-146. 14 511. Monika J. Pandarkar 16 June 2022

15. Thank you