enzyme classification and nomenclature.pptx

enzymes are proteinaeous, enzyme classifiation, international units of biochemist, nomenclature, enzyme commission numbers, IUB

1. Classification of Enzymes Instructed by SHANES

2. EC.1- Oxidoreductases Catalyze oxidation-reduction reactions where electrons are transferred. These electrons are usually in the form of hydride ions or hydrogen atoms. General reaction;

3. Example..

4. EC.2- Transferases Catalyze group transfer reactions. The transfer occurs from one molecule that will be the donor to another molecule that will be the acceptor. General reaction;

5. Example..

6. Ec.3- Hydrolases Ca talyzes the break down of bond of substrate by using water . When the hydrolase acts on amide, glycosyl, peptide, ester, or other bonds, they not only catalyze the hydrolytic removal of a group from the substrate but also a transfer of the group to an acceptor compound. General Reaction;

7. Example..

8. EC.4- lyases C atalyzes the addition or removal of group from one substrate to another by mechanism other than hydrolysis and creating double bond . General reaction;

9. Example..

10. Ec.5- isomerases Catalyze reactions that transfer functional groups within a molecule so that isomeric forms are produced. These enzymes allow for structural or geometric changes within a compound. General reaction;

11. Example..

12. Ec.6- Ligases Catalyze the synthesis of two molecular substrates into one molecular compound with the release energy. These reactions are coupled to the cleavage of ATP. General reaction;

13. Example..

14. Ec.7- Translocases Catalyze the movement of ions or molecules across membranes or their separation within membrane. General reaction; AX + B side 1 || = A + X + || B side 2

15. Example.. A clear example of an enzyme that follows this scheme is  H+-transporting two-sector ATPase: ATP + H2O + 4 H+side 1 = ADP + phosphate + 4 H+side 2

16. Questions Why is systematic naming of enzyme important? On what based ,enzymes are classified? What is meant by EC ? What is the function of transferase? Differentiate between hydrolase and lyase ? Which class of enzyme involved all digestive enzyme? DNA polymerase is a enzyme of what class?