exp 12.pptx

PHARMACEUTICS PPT

1. Exp. No. 12 To prepare and submit calamine lotion.

2. Reference(s) Gaud R.S., Gupta G.D.; Practical pharmaceutics; I edition reprint 2009; S. K. Jain for CBS Publishers and distributors Pvt. Ltd. New Delhi; page no. 105 Jain N.K., Sharma S.N.; A Text Book Of Professional Pharmacy; V edition reprint 2014; M. K. Jain for Vallabh Prakashan Delhi; page no 234 Mehta R.M.; Dispensing Pharmacy; IV edition reprint 2014; M. K. Jain for Vallabh Prakashan Delhi; page no. 166

3. Requirements Calamine, zinc oxide, bentonite, sodium citrate, liquefied phenol, glycerine, rose water

4. Theory Lotions are liquid or semi-liquid preparations that contain one or more active ingredients in an appropriate vehicle. Lotions may contain antimicrobial preservatives and other appropriate excipients, such as stabilizers. Lotions are intended to be applied to the unbroken skin without friction. Lotions are suspensions of solids in an aqueous medium. Some lotions are, in fact, emulsions or solutions

5. Formula Ingredients Quantity Uses Calamine 15g Astringent, soothing agent Zinc oxide 5g Astringent, protective agent Bentonite 3g Suspending agent Sodium citrate 0.5ml Buffering agent, chelating agent, Liquefied phenol 0.5ml Antiseptic, preservative Glycerine 5 ml Humectant Rose water, sufficient to produce 100ml Perfumed vehicle

6. Procedure Prepare sodium citrate solution in 70mlrose water. Triturate calamine, zinc oxide and bentonite with citrate solution. Add liquefied phenol and mix. Add glycerine and sufficient rose water to produce 100ml.

7. Category: Protective Storage: It should be stored in a well closed container because zinc oxide gradually converts into zinc carbonate due to atmospheric carbon dioxide Uses: Protective and mild antiseptic

8. Result

9. Label for Preparation

10. Video link https://youtu.be/EBX5_A6qikA https://youtu.be/z0MXmN-4mEI https://youtu.be/cCO5vS0iLyI