Gross & microscopy of FGT.pptx gross and micro

Gross & microscopy of FGT.pptx gross and micro

1. WHO Classification of tumors of the Fallopian Tube

2. Serous Adenofibroma Papilloma SBT HGSC Fimbria, U/L Intraluminal Fimbrial end Intraluminal or fimbrial end < 1 cm Papillary brownish proli . <3 cm attached to tubal mucosa 2-23 cm Papillary or solid growth Mixed epithelial 7 mesenchymal component c/o delicate branching fibrovascular stalks l/b bland non- ciliated epithelium Features same as ovarian SBT Features same as ovarian HGSC DD- Metaplastic papillary tumor

3. Metaplastic Papillary Lesion Post partum women

4. Paratubal Cyst Pediatric & adolescents Thin Walled fluid filled cyst b/w ovary & fallopian tube l/b cuboidal or ciliated epitheium

5. Tubal Hyperplasia Benign epithelial proliferation of fallopian tube Incidental finding Discrete foci of pseudostratification Loss of polarity No nuclear atypia or mitotic activity

6. Tubo -Ovarian Abscess Late complication of PID Gross- Marked distortion of tubal & ovarian anatomy Acute & chronic inflammation, necrosis, abscess formation & fibrosis

7. Salpingitis Isthmica Nodosa Diverticulosis of epithelium of fallopian tube with smooth muscle hypertrophy +/- hyperplasia Strong association with both infertility & ectopic pregnancy Gross: > 1 discrete firm nodules in proximal tube covered by smooth normal serosa

8. WHO Classification of tumors of Gestational T rophoblastic Disease

9. WHO Classification of tumors of the Uterine Corpus

10. Endometrial Hyperplasia without atypia Increased gland to stroma ratio Proliferation of endometrial glands of irregular size & shape No significant cytological atypia

11. Endometrial Atypical Hyperplasia/ Endometrioid Intraepithelial Neoplasia Crowded glandular architecture Altered epithelial cytology, distinct from surrounding endometrium &/or entrapped non-neoplastic glands

12. Endometrioid Carcinoma Gross: Exophytic or diffusely infiltrative Varying degrees of necrosis & hemorrhage seen Microscopic Features: Villoglandular architecture with smooth outline c/o cells that are columnar with pseudostratified nuclei, granular eosinophilic cytoplasm Mild- mod nuclear atypia with inconspicuous nucleoli Nucleoli visible in high grade EEC Stroma Invasion

13. FIGO Grading criteria Grade 1- < 5% Grade 2- 6-50% Garde 3- >50% solid, non glandular, non squamous growth

14. WHO Classification of tumors of the Uterine Cervix

15. WHO Classification of tumors of the Vagina

16. WHO Classification of tumors of the Vulva