Microscope An instrument that makes small objects look larger. A. The Inventors : 1. 1590 Hans & Zaccharius Janssen a. Dutch lens grinders b. made the 1 st compound microscope (has more than one lens)
2. 1609 Galileo Improved on the Janssen’s ideas Made a microscope that could be focused
3. Anton Van Leeuwenhoek 1632-1723 Dutch scientist who greatly improved lens grinding 1 st to see bacteria, yeast, blood cells, and life in pond water Made people aware of microscopic life
And now, time out for a word from your sponsor….
Leeuwenhoe k Unlikely scientist A tradesman (a fabric merchant, a surveyor, a wine assayer, and a minor city official) No university degrees Knew no language other than Dutch
…oh Leeuwenhoek But he had skill, he was hardworking, had an endless curiosity, and he kept an open mind His researches opened up the world of microscopic life to scientists
His Inspirations… Leeuwenhoek saw Robert Hooke’s illustrated book Micrographia which showed Hooke’s own observations with a microscope
Anton Van Leeuwenhoek’s 1632-1723 Made over 500 simple “microscopes” Microscopes were simply powerful magnifying lenses Specimens were mounted on the sharp point that sticks up in front of the lens A tradesman (a fabric merchant, a surveyor, a wine assayer, and a minor city official) No university degrees Knew no language other than Dutch Leeuwenhoek saw Robert Hooke’s illustrated book Micrographia which showed Hooke’s own observations with a microscope Dutch scientist who greatly improved lens grinding 1 st to see bacteria, yeast, blood cells, and life in pond water Made people aware of microscopic life
Anton’s Microscopes: Compound microscopes invented around 1595 But could only magnify 20-30x But Leeuwenhoek’s simple microscope could magnify 200x (what a great lens grinder)! Hired a skilled illustrator to draw the things he saw
All good researchers share their findings…. 1673 Leeuwenhoek began writing letters to the Royal Society of London describing what he’d seen with his microscopes
Eeeeewww… 17 September 1683 wrote about observations on his own plaque “ a little white matter, which is as thick as if it ‘twere batter ” Repeated observations on two men who had never cleaned their teeth Found “ an unbelievingly great company of living animalcules, a-swimming more nimbly than any I had ever seen up to this time. Moreover…the animalcules… seemed to be alive .”
WEE BEASTIES! These were the first observations of living bacteria ever recorded! He soon called them his “wee beasties”!
Oooh What He Saw! Foraminifera Blood cells
CONGRATULATIONS ANTON! After 50 years of writing to the Royal Society of London, he was elected a full member Joined Robert Hooke, Robert Boyle, Christopher Wren and other great scientists of his day
…Now, back to your notes…
B. Compound Light Microscope Has two or more lenses Used to study cells Most magnify to 400x Most powerful magnifies 2000x Most have 3 objectives Low Medium High 6. Specimen MUST be thin (allows light to pass through)
C . Electron Microscope Uses electrons and magnets Very powerful – magnifies 2 million x or more Show specimens in 3-D Requires TV to view image
1. Which of the following is NOT one of the people credited with inventing the microscope? A. Hans LippersheyNot Quite! B. Marie CurieCorrect ! C . Hans JanssenNot Quite! D.Zacharias Janssen
2. All of our _____________ exist because of our ability to study illnesses through the lens of a microscope. A. Illnesses B. Cells C. Medicines D. Protein
3. Which of the following is the BEST evidence that microscopes have greatly improved over time? A. “The first microscopes made by the Janssens magnified objects by nine times. Today, the world’s strongest microscope helps us see objects at 200,000 times their size!”Correct ! B. “One tool that helps people understand the world more clearly is the microscope.”Not Quite! C. “Looking through the tube, they found that it made objects on the other end look bigger! Another eyeglass maker named Hans Lippershey made a similar tool around the same time.”Not Quite! D. “Microscopes have helped people learn a lot about our world.”
4-5. Why is it that microscopes were considered an important tool used by biologists in conducting their laboratory research?