Human blood brain barrier

Details on Neuromics' 3-D Blood-Brain Barrier Model. This model is designed for drug discovery and tox assays. The goal is to provide users with in vivo like results.

1. Human Blood Brain
Barrier
Characterized, Tested and Discovery Ready

2. Features
•Populated with 21-CFR primary human cells
•Engineered hydrogels to mimic in vivo ECM
•Stiffness matters
•Customizable
•For high throughput screening 96 wells
•Cell types to order

3. TEER (trans endothelial electrical resistance) in
BBB model
•TEER in BBB model
reaches more than 150
Ω×cm2 , and maintains a
plateau up to 7 days.
•Key to validating tight
gap junctions

4. Permeability Assay
•Protocol optimized for permeability
assays
•Drug discovery and toxic assays

5. Apparent Permeability Coefficients (P
app)

6. Evaluating the BBB-permeability

7. Customers