Hypertensive retinopathy,Dr M SAQUIB

HYPERTENSIVE RETINOPATHY
PREGNANCY INDUCED HYPERTENSION
MALIGNANT HYPERTENSION

1. RETINA – HYPERTENSIVE RETINOPATHY 21st May2020
May 2020AL KERATITIS
DR M SAQUIB
MBBS,MS , FSCEH DELHI,FHVDESAI PUNE,
EX REGISTRARA JNMCH,AMU
CONSULTANT OPHTHALMOLOGIST
HOD D/O OPHTHALMOLOGY
G.S .MEDICAL COLLEGE
Founder sec: MEDICS India ,
[email protected] , 9634123800

3. Clinical Presentation
•RETINOPATHY –Auto regulation ,Sympathetic
stimulation


•CHOROIDOPATHY -


•OPTIC NEUROPATHY-

4. Pathogenesis
•Vasoconstriction – Retinal Arteriole (Young),
• Augmented Arteriosclerotic Retinopathy
Choroidal Vessels –RPE ischemia
Peripapillary Choroid –Optic N Ischemia

•Arteriosclerotic Changes- Arteriolar Reflex, A-V
Nipping, Senile sclerosis
•Increased Vascular Permeability- Hypoxia
Haemorhages, Retinal oedema, macular oedema ,focal intraretinal
periarterial transudates(FIPT), Disc oedema

5. Staging Of Hypertensive Retinopathy -KEITH WAGNER

7. Chronic Hypertensive Retinopathy

1.HYPERTENSION WITH INVOLUTIONARY
(SENILE)SCLEROSIS

Augmented Arteriosclerotic Retinopathy >50 year Age


2..CHRONIC HYPERTENSION WITH COMPENSATORY
ARTERIOLAR SCLEROSIS
Young , prolioferative and fibrous change in the Tunica Media .
Compensatory arteriosclerotic sclerosis)
Albuminuric or Renal Retinopathy

8. FUNDUS CHANGES
1.Generalised arterial narrowing
2 Focal arteriolar Narrowing
3. Arterio Venus nicking A: V , 3:4 N
4 Arteriolar Reflex Changes
5. Retinal Haemorrhages (Superficial )
6. Hard Exudates
7. Cotton Wool Spots

11. Hard Exudates,Soft Exudates , Flame shaped Haemorhage

12. A V NICKING

14. Grade 3-4 Hypertensive Retinopathy. A 56-year old patient presented with acute onset vision loss. Fundus examination revealed Grade 3-4
hypertensive retinopathy changes including arterio-venous crossing changes, macular
star and cotton wool spots.
Grade 3-4 Hypertensive Retinopathy. A 56-year old patient presented with acute
onset vision loss. Fundus examination revealed Grade 3-4 hypertensive
retinopathy changes including arterio-venous crossing changes, macular star and
cotton wool spots.

15. Copper-wiring, ArterioVenous nicking and silver-
wiring seen in a patient with hypertensive
retinopathy

16. Copper wiring , Silver Wiring

17. flame-shaped hemorrhages in the superficial layers of the retina and cotton-
wool patches caused by occlusion of the precapillary arterioles with
ischemic infarction of the inner retina.

Long-standing hypertension can produce arteriolar sclerotic vascular
changes, such as copper or silver wiring of the arterioles, as shown by the
two arrows in the figure, or arteriorvenous nicking.

chronic hypertension is lipid exudates resulting from abnormal
vascular permeability, as shown by the arrow at left.

swelling of the optic disc, seen here by the blurring of the temporal disc
margins. Hallmark of malignant hypertension
.

19. MALIGNANT HYPERTENSION
High BP Retinal vasculature lose auto regulation (190/120 mmHg))
Headache,Blurred vision , Altered sens,Dysnoea
•Acute Hypertensive Retinopathy –
Spasm of arteriole
Hyperplastic arteriosclerosis, concentric hyperplastic arteriosclerosis-
onion peeling – necrosis & inflammation- Necrotizing vsculitis
•Superficial Retinal Haemorhages
•Focal intraretinal periarteriolar transudates (FIPTS)-Due to
deposition of macro molecule along arteriole due blood
retinal barrier break ,Small white focal lesion
•Cotton wool spot
•Capillary Obliteration-Micro aneurysm,shunt vessels,
collateral

21. Acute Hypertensive Choroidopathy –

•Acute ischemic change in choriocapillaries ,Focal white
spot
•Elschnig’s spot – Small black spot surrounded by yellow
haloes-Due to RPE infarction
•Siegrist streaks- fibrinoid necrosis pigment along
choroidal arteriole

•Serous Neurosensory Retinal Detachment

22. ACUTE HYPERTENSIVE OPTIC NEUROPATHY
•Optic Disc Oedema and Haemorrhage ----AION
•Disc Pallor

25. Acutely, the patient complains of mild bilateral visual loss and
blood pressure is 224/68 mmHg. Note the attenuation of retinal
arteries, dilation of the veins, cotton wool spots (soft exudates)
(white circle), flame shaped hemorrhages (white arrowheads), hard
exudates (white arrow), and Elschnig spots (star). There is macular
edema bilaterally, which explains the decreased visual acuity.
•Second row of photographs: Retinal fluorescein angiography
showing hyperfluorescence at the level of the Elschnig spots (star),
and microaneurysms (white arrows).
•Third row of photographs: Retinal appearance two weeks later
(after normalization of blood pressure). Note the improvement of
macular edema and the increased hard exudates.
•Bottom row of photographs: Three months later, the cotton wool
spots and retinal hemorrhages have resolved. The arterial
attenuation persists, and the veins are less dilated. Both optic
nerves have become slightly pale.

27. Stage III/IV hypertensive retinopathy There is mild bilateral optic
nerve edema. Note the arteriovenous nicking (white arrows), the
flame hemorrhage (white arrowhead), the boat-shaped hemorrhage
(star), and the arteriolar narrowing (black arrows).

28. Severe stage IV hypertensive retinopathy with bilateral optic nerve head oedema in
the setting of malignant hypertension c.

29. Hypertensive choroidopathy
•Not possess the autoregulatory capacity of the retinal vasculature .
•Divided into three constrict, leading to necrosis of the
choriocapillaris and retinal pigment epithelium and the
accumulation of exudates in phases. During the acute ischemic
phase, choroidal arterioles he subretinal space. The clinical fundus
findings during this phase include white areas (a manifestation of
retinal pigment epithelium necrosis), and focal serous retinal
detachment most often involving the macula and peripapillary
region. Retinal fluorescein angiography shows patches of
hypoperfused choriocapillaris, particularly in the central region of
the macula.

30. Staging Of Hypertensive Retinopathy -KEITH WAGNER

32. Wong And Mclntosh Classification

33. Pregnancy Induced Hypertension
•Toxaemia of Pregnancy-
•Hypertension, Proteinuria , Generalised oedema
•BP – 160/100 ,200/130
•Fundus- Narrowing of nasal arteriole ----
generalised ----spasm –cotton wool spot,
Haemorhagre
•Retinal oedema /Exudation – Macular star or
Retinal Detachment ( Good Prognosis)

35. •Reversible retinopathy
•Preorganic stage- Respond treatment , Continue
Pregnancy

•Hypoxic Retinopathy –cotton wool spot, Retinal
oedema ---Pregnancy termination – Complete
visual lose