INTRODUCTION TO HERBAL FORMULATIONS.pptx

Herbal formulation shall mean a dosage form consisting of one or more herbs in specified quantities to provide specific nutritional, cosmetic benefits, or other benefits meant for use to diagnose treat, mitigate diseases of human beings or animals.
Herbal preparations are obtained by subjecting herbal substances to treatments such as extraction, distillation, expression, fractionation, purification, concentration or fermentation.
These include comminuted or powdered herbal substances, tinctures, extracts, essential oils, expressed juices and processed exudates.
Herbal cosmetic is defined as “ the beauty products, which possess desirable physiological activities such as skin healing, smoothening, appearance enhancing properties with the help of herbal ingredients.”
almond oil
olive oil
rosemarry oil
sandalwood oil

1. INTRODUCTION TO HERBAL FORMULATIONS ARCHANA B CHAVHAN M.PHARM (QA) KYDSCT’S COP SAKEGAON BHUSAWAL

2. INTRODUCTION Herbal formulation shall mean a dosage form consisting of one or more herbs in specified quantities to provide specific nutritional, cosmetic benefits, or other benefits meant for use to diagnose treat, mitigate diseases of human beings or animals. Herbal preparations are obtained by subjecting herbal substances to treatments such as extraction, distillation, expression, fractionation, purification, concentration or fermentation. These include comminuted or powdered herbal substances, tinctures, extracts, essential oils, expressed juices and processed exudates.

3. TYPES OF HERABAL FORMULATIONS

4. Gutika Vati Asava Arista Arka Taila Churna Bhasma Herbal tablets Herbal capsules Herbal syrup Herbal ointments Herbal emulsions Herbal mixtures Aromatic waters Traditional dosage form Conventional dosage form Types of herbal formulations

5. Novel dosage form Phytosomes Nanoparticles Liposomes Transferosomes Ethosomes

6. Herbal tablets Method of preparation Wet granulation Dry granulation Direct compression Coating e.g. Gikgo biloba tablets, neeri tablet, cystone tablet Evaluation of tablets Apperance Uniformity of thickness Weight variation Hardness Friability Dissolution test Drug content uniformity

7. Herbal capsules Method of preparation By automated machines, involving dipping, spinning, drying, stripping, trimming & joining the capsule Gelatine is the most important content of dipping solution Evaluation of capsules Size, shape, weight, colour Content of active ingredient Content uniformity In vitro disintegration test Dissolution test e.g. ginseng capsule, DIABSAN capsule

8. Herbal syrup Simple syrup Flavoured syrup Medicated syrup Evaluation of syrup Consistency pH determination Assay of active content Viscosity e.g. acacia syrup, cocoa syrup, ipecac syrup

9. Herbal ointments Method of preparation Incorporation method Fusion method Evaluation Skin irritation test Applicability Spreadability Viscocity

10. HERBAL EMULSION Method of preparation Dry gum method Wet gum method Bottle method Evaluation parameters Cracking Creaming Phase inversion e.g. Peppermint emulsion

11. HERBAL MIXTURES EVALUATION PARAMETERS Determination of pH Viscosity Sedimentation rate Measurement of zeta potential

12. NOVEL DOSAGE FORMS PHYTOSOMES It is vesicular drug delivery system in which the phytoconstituents of herbal extract and bound by lipid membrane LIPOSOME These are biosphere shaped vesicles usually with 0.05-5um diameter NANOPARTICLES Particles between 1 -100 nm in size having several advantages

13. HERBAL COSMETICS Herbal cosmetic is defined as “ the beauty products, which possess desirable physiological activities such as skin healing, smoothening, appearance enhancing properties with the help of herbal ingredients.”

14. Almond oil Biological source: prunus amygdalus Family : Rosaceae Chemical constituent : Mixture of glycerides of oleic( 86%), linoleic (17%), palmitic (5%), myristic (1%) Uses: As an emolliet and an ingredient in cosmetics Used as laxative, flavouring agents

15. LAVENDER OIL Biological source: lavandula angustifolia Family : labiatae Chemical constituents: A- pinene , limonene, 1,8 cineole, 3-octanone, linalool Uses: Treat minor burn wound Has soothing and calming effect on the nerves, relieving depressio .

16. Olive oil Biological source: It is the fixed oil expressed from the ripe fruit of Olea europaea Linne . Family: Oleaceae Chemical Constituents: The olive oil contains the triglycerides mainly in the from of Olein , palmitin and linolein Therapeutic Uses: It is used as nutrient, demulcent and as mild Laxative Cosmetic Uses: It is used to soften the skin and crusts in eczema It also used as an ingredient of ear wax

17. Rosemary Oil: Source: Rosemary oil is distilled from the flowering tops of leafy twigs of Rosmarinus officinalis Family: Lamiaceae Chemical Constituents: The main constituents of the oils were p-cymene, linalool, gamma- terpinene , thymol , beta- pinene , alpha- pinene and eucalyptol. The oil consisted of monoterpenic hydrocarbons, oxygenated monoterpenes and sesquiterpene hydrocarbons .

18. Therapeutic Uses : Memory . Taking rosemary by mouth might somewhat improve memory in young adults. May Help Relieve Pain. Reduce Joint Inflammation . Cosmetics Uses: Stimulates Hair Growth. It deeply hydrates skin and can be used instead of moisturizer. Its anti-bacterial and anti-inflammatory properties help battle acne. It helps reduce the appearance of blemishes and can be used to lighten stretch marks.

19. Sandal Wood oil Source : Sandalwood oil is obtained by distillation of sandalwood, Santalum album Linn., Family : Santalaceae . Chemical Constituents The main odorous and medicinal constituent of Sandal-wood is santalol . This primary sesquiterpene alcohol forms more than 90% of the oil and is present as a mixture of two isomers, α- santalol and β- santalol , the former predominating. The other constituents reported are hydrocarbons santene , nor- tricycloekasantalene , α-, and β- santalenes .

20. Therapeutic Uses: A chemo-protective action on liver carcinogenesis in mice has been demonstrated. Used for symptomatic treatment of DYSURIA(medical term for pain or discomfort when urinating) Cosmetics Uses: Sandalwood oil is highly used in perfumery creations and finds an important place in soaps, face creams, and toilet powders.